In the industrialized countries university research and state-financed research are increasingly evaluated from the point of view of their contribution to technology transfer, industrial innovation, and the competitiveness of national industries. Political debates on the viability of orienting basic research toward practical applications are paralleled by discussions, among social scientists, about the risks and opportunities of political direction over science. These debates are the frame of reference for this study, which analyzes the differences between basic and applied research, their correlates (...) and consequences, in high-temperature superconductor research in the Federal Republic of Germany. It will be shown that basic and applied research are fundamentally different in their social organization, their research goals, and their research strategies. These differences are in contrast to the call of science policy for more intense interaction and assimilation. Nevertheless, there are conditions under which basic or applied re searchers will partially follow "foreign" orientations and strategies. These conditions may, in part, be shaped by policy decisions. (shrink)