This paper is an attempt to give a general explanation of pragmatic aspects of linguistic negation. After a brief survey of classical accounts of negation within pragmatic theories (as speech act theory, argumentation theory and polyphonic theory), the main pragmatic uses of negation (illocutionary negation, external negation, lowering and majoring negation) are discussed within relevance theory. The question of the relevance of negative utterance is raised, and a general inferential schema (based on the so-called invited inference) is proposed and tested (...) for the main uses of negation discussed in the paper. (shrink)