Within the philosophy of science there has been a great deal of rather vague talk about the 'heuristic fruitfulness' (or what Peirce called the 'esperable uberty') of theories. It is my aim in the present paper to add some precision to these discussions by linking this 'fruitfulness' to the satisfaction of certain heuristic criteria. In this manner the demarcation between 'discovery' and 'pursuit' becomes blurred. As a case study, I present the competition between the paraparticle and colour models of quarks (...) in the late 1960s. I argue that the eventual appraisal of the latter as the more fruitful of the two was based on the incorporation of a particular symmetry principle, regarded as a heuristic guideline, rather than on non-epistemic factors concerning 'cognitive resources' and the like. (shrink)

A critical examination of the charge of self-refutation, particularly as leveled by orthodoxy-defending philosophers against those maintaining epistemologically unorthodox, especially relativistic or skeptical, views. Beginning with an analysis of its classic illustration in Plato’s *Theaetetus* as leveled against Protagoras’s “Man is the measure ...,” I consider various aspects of the charge, including logical, rhetorical, pedagogic, affective, and cognitive.

This paper explores the gray area of questionable research practices (QRPs) between responsible conduct of research and severe research misconduct in the form of fabrication, falsification, and plagiarism (Steneck in SEE 12(1): 53–57, 2006). Up until now, we have had very little knowledge of disciplinary similarities and differences in QRPs. The paper is the first systematic account of variances and similarities. It reports on the findings of a comprehensive study comprising 22 focus groups on practices and perceptions of QRPs across (...) main areas of research. The paper supports the relevance of the idea of epistemic cultures (Knorr Cetina in: Epistemic cultures: how the sciences make knowledge, Harvard University Press, Cambridge, 1999), also when it comes to QRPs. It shows which QRPs researchers from different areas of research (humanities, social sciences, medical sciences, natural sciences, and technical sciences) report as the most severe and prevalent within their fields. Furthermore, it shows where in the research process these self-reported QRPs can be found. This is done by using a five-phase analytical model of the research process (idea generation, research design, data collection, data analysis, scientific publication and reporting). The paper shows that QRPs are closely connected to the distinct research practices within the different areas of research. Many QRPs can therefore only be found within one area of research, and QRPs that cut across main areas often cover relatively different practices. In a few cases, QRPs in one area are considered good research practice in another. (shrink)

: The main contribution of this paper for social studies of scientific practice is to use and further elaborate the concept of experimental system. It is expanded from mere epistemic concerns to also incorporate the built-in practicality and societal relevance of scientific research. For this, an analysis of object construction by a potato-biotechnology research group is presented. The group's object of activity is conceptualized as a dual one comprising both the epistemic and applied objectives. The application object points to the (...) virus-resistant cultivated potato under construction, the epistemic object to the knowledge on the virus-resistance mechanism. Two major phases of the group's work are perceived as distinct experimental systems. The transition between them is analysed in terms of a gradual evolution characterised by network collaboration, ad hoc improvization, resistance, opportunism and informal interaction. (shrink)

Research integrity is usually discussed in terms of responsibilities that individual researchers bear towards the scientific work they conduct, as well as responsibilities that institutions have to enable those individual researchers to do so. In addition to these two bearers of responsibility, a third category often surfaces, which is variably referred to as culture and practice. These notions merit further development beyond a residual category that is to contain everything that is not covered by attributions to individuals and institutions. This (...) paper discusses how thinking in RI can take benefit from more specific ideas on practice and culture. We start by articulating elements of practice and culture, and explore how values central to RI are related to these elements. These insights help identify additional points of intervention for fostering responsible conduct. This helps to build “cultures and practices of research integrity”, as it makes clear that specific times and places are connected to specific practices and cultures and should have a place in the debate on Research Integrity. With this conceptual framework, practitioners as well as theorists can avoid using the notions as residual categories that de facto amount to vague, additional burdens of responsibility for the individual. (shrink)

This paper focuses on the role of regulation in the shaping new scientific facts. Fleck chose to study the origins of a diagnostic test for a disease seen as a major public health problem, that is, a ‘scientific fact’ that had a direct and immediate influence outside the closed universe of fundamental scientific research. In 1935, when Fleck wrote his book, Genesis and development of a scientific fact, he believed that the tumultuous early history of the Wassermann reaction had come (...) to an end, and that this reaction was successfully stabilized through the standardization of laboratory practices and thanks to the rise of a specific professional segment—the serologists. He could not have predicted that in the 15 years that followed the publication of his book, regulatory measures—barely metioned in his historical narrative—would play a key role in the destabilization of the original meaning of this reaction. The introduction of mass screening for syphilis—mainly via legislation that introduced obligatory premarital tests and promoted the testing of pregnant women—weakened in fine the link between Wassermann serology and infection by the etiological agent of syphilis, the bacterium Treponema pallidum. Fleck elected to study the Wassermann reaction because of its novelty, its complexity, and because it became the focus of a controversy regarding its origins. However, the Wassermann reaction was also one the first examples of a medical technology regulated by the state and incorporated into legal dispositions. It may therefore be seen as an exemplary case of the close intertwining of scientific investigations, their practical applications and regulatory practices. (shrink)

The aim of this paper is to discuss a key question in the history and philosophy of medicine, namely how scholars should treat the practices and experimental hypotheses of modern life science laboratories. The paper seeks to introduce some prominent historiographical methods and theoretical approaches associated with biomedical research. Although medical scientists need no convincing that experimentation has a significant function in their laboratory work, historians, philosophers, and sociologists long neglected its importance when examining changes in medical theories or progress (...) in scientific knowledge. The reason appears to have been the academic influence of the then dominant tradition in the history of ideas, but was also due to a misconception of what could usefully be termed the view on “historical ontology.” During the last two decades, there have been many books and research articles that have turned towards the subject, so that the study of experimental practice has become a major trend in the contemporary history and philosophy of medicine. A closer look at the issue of laboratory research shows that concepts in medicine and the life sciences cannot be understood as historically constant, free-standing ideas, but have to be regarded as dependent on local research settings. They often carry particular “social memories” with them and thus acquire important ethical implications. (shrink)

In science studies the laboratory has been positioned as a privileged place for understanding scientific practice. Laboratory studies foregrounded local spaces of knowledge production in the natural sciences, and in doing so made the laboratory key to social science epistemologies. This article explores how laboratory studies and observational methods have been tied up together in the science and technology studies project of making scientific practice visible. The author contrasts powerful rhetorics of witnessing and revelation in some significant STS texts with (...) the negotiated and partial ways in which observing science work is done in social science practice. Drawing on empirical material generated with bioscientists and social scientists, the article explores how researchers may resist the observational gaze and mark aspects of knowledge work as private and solitary. The author concludes by arguing that epistemologies of vision point to some unsettling parallels between the study of knowledge-making in STS and audit regimes in contemporary research, and considers how both might devalue invisible work. This analysis suggests that there is a need to reconsider the significance of thinking in the ensemble of knowledge production practices for methodological, epistemological, and strategic reasons. (shrink)

Along with anatomical dissection, attendance at hospital autopsies has historically been seen as an essential part of medical education. While the use of the dead body for teaching purposes is losing favour in Australian medical schools, this shift is preceded by a significant decline in the rate of autopsies nationwide (and internationally). The decline of the autopsy has particular implications for pathology training where the capacity to perform an autopsy is a requirement. Rather than join the debates in medical literature (...) about the merits of these shifts, this article goes behind the scenes of a hospital mortuary to study autopsy training and practice from the perspective of those who undertake it. The article first introduces the discipline of pathology—‘the science of medicine’—which is built upon centuries of post-mortem study and establishes the fact of the disappearing autopsy. The article then draws upon data from anthropological fieldwork in a Department of Anatomical Pathology to discuss some of the ways trainees manage the work of cutting up the dead. Concepts such as detachment, immersion and disciplinary practice are covered in during this unveiling of everyday practice in a hospital mortuary. (shrink)

This article asks whether an interdisciplinary "critical science studies" (CSS) is possible between a critical theory in the Frankfurt School tradition, with its commitment to universal standards of reason, and relativistic sociologies of scientific knowledge (e.g., David Bloor's strong programme). It is argued that CSS is possible if its practitioners adopt the epistemological equivalent of Rawls's method of avoidance. A discriminating, public policy–relevant critique of science can then proceed on the basis of an argumentation theory that employs an immanent standard (...) of relevance, which is illustrated by drawing on Helen Longino's critique of behavioral theory. (shrink)

The paper tries to show that an evolutionary perspective helps us to address what is called the adaptation problem, that is, the remarkable coherence, and seemingly successful design, existing between our cognitive tools and the phenomena of the material world. It argues that a fine-grained description of the structure and function of experimental techniques—as a special type amongst evolving scientific practices—is a condition for a better understanding and, ultimately, an explanation of how adaptation among the heterogeneous elements of experimental knowledge (...) is attained. Some apparently contradictory features of techniques, such as their high context-dependency and their capabilities to reproduce and diversify outside their original contexts, are addressed with the help of the concepts of technical variation and the historical entrenchment of phenomena in techniques. In order to do so, a case-study on the construction of satellite-DNA and the evolution of nucleic acid hybridization, a research project carried out by Roy J. Britten and his colleagues in the 1960s, is presented in detail. This case illustrates the close relationship existing between the evolution of techniques and the stabilization of phenomena in experimental biology. (shrink)

This paper explores whether we can interpret the notion of ‘forensic culture’ as something akin to what Knorr-Cetina called an ‘epistemic culture’. Can we speak of a ‘forensic culture’, and, if so, how is it similar to, or different from, other epistemic cultures that exist in what is conventionally called ‘science’? This question has important policy implications given the National Academy Science’s recent identification of ‘culture’ as one of the problems at the root of what it identified as ‘serious deficiencies’ (...) in U.S. forensic science and ‘scientific culture’ as an antidote to those problems. Finding the NAS’s characterisation of ‘scientific culture’ overly general and naïve, this paper offers a preliminary exploration of what might be called a ‘forensic culture’. Specifically, the paper explores the way in which few of the empirical findings accumulated by sociologists of science about research science seem to apply to forensic science. Instead, forensic science seems to have developed a distinct culture for which a sociological analysis will require new explanatory tools. Faithful sociological analysis of ‘forensic culture’ will be a necessary prerequisite for the kind of culture change prescribed by external reformist bodies like the NAS. (shrink)

Laboratory experimentation was once considered impossible or irrelevant in economics. Recently, however, economic science has gone through a real ‘laboratory revolution’, and experimental economics is now a most lively subfield of the discipline. The methodological advantages and disadvantages of controlled experimentation constitute the main subject of this thesis. After a survey of the literature on experiments in philosophy and economics, the problem of testing normative theories of rationality is tackled. This philosophical issue was at the centre of a famous controversy (...) in decision theory, during which a methodology of normative falsification was first articulated and used to assess experimental results. In the third chapter, the methodological advantages of controlled experimentation are illustrated and discussed with examples taken from the experiments on the so-called ‘preference reversal’ phenomenon. Laboratory testing allows to establish with a high degree of certainty that certain phenomena lie behind the experimental data, by means of independent testing, elimination of alternative hypotheses, and the use of different instruments of observation. The fourth chapter is devoted to a conceptual analysis of the problem of ‘parallelism’. This is the problem of inferring from the occurrence of a phenomenon in the laboratory, to its instantiation also in non-laboratory environments. Experimental economists have discussed parallelism at length, and their views are presented and criticised. Eventually, it is argued that parallelism is a factual matter and as such can only be established on empirical grounds. The fifth chapter provides an example of how one can argue for parallelism, focusing on the case of experimentation on the ‘winner’s curse’ phenomenon. The role of experiments as ‘mediators’ between theoretical models and their target domain of application is illustrated, and the structure of parallelism arguments analysed in detail. Finally, in the last chapter, economic experiments are compared to simulations, in order to highlight their specific characteristics. (shrink)

The dramatic and ongoing changes in the funding of science have stimulated interest in an economics of scientific knowledge, which would investigate the effects of these changes on the scientific enterprise. Hands has previously explored the lessons for such an ESK from the existing precedent of the sociology of scientific knowledge. In particular, he examines the philosophical problems of SSK and those that any ESK in its image would face. This paper explores this argument further by contending that more recent (...) literature in SSK exposes even deeper philosophical problems than those identified by Hands. Meaning finitism has emerged as the philosophical core of SSK. An examination of the profound problems with this position is used to show that an underlying extensionalism is the root of SSK's intractable philosophical difficulties, and to illustrate the entirely different approach of a critical philosophy that is advocated in its place. In this way, the project of an ESK is shown to depend upon a critical philosophy. (shrink)

The modern understanding of radiation got its start in 1895 with X-rays discovered by Wilhelm Röntgen, followed in 1896 by Henri Becquerel’s discovery of radioactivity. The development of the study of radiation opened a vast field of research concerning various disciplines: chemistry, physics, biology, geology, sociology, ethics, etc. Additionally, new branches of knowledge were created, such as atomic and nuclear physics that enabled an in-depth knowledge of the matter. Moreover, during the historical evolution of this body of knowledge a wide (...) variety of new technologies was emerging. This article seeks to analyze the characteristics of experimental research in radioactivity and microphysics, in particular the relationship experience-theory. It will also be emphasized that for more than two decades, since the discovery of radioactivity, experiments took place without the theory being able to follow experimental dynamics. Some aspects identified as structural features of scientific research in the area of radiation and matter will be addressed through historical examples. The inventiveness of experiments in parallel with the emergence of quantum mechanics, the formation of teams and their relationship with technology developed from the experiments, as well as the evolution of microphysics in the sense of “Big Science” will be the main structural characteristics here focused. The case study of research in radioactivity in Portugal that assumes a certain importance and has structural characteristics similar to those of Europe will be presented. (shrink)

This article argues that the long-standing tension in Jeffrey Alexander’s work between theoretical multidimensionality and socio-cultural idealism has intensified in his recent writings, to problematical effect. Whilst Alexander has shifted of late towards a more substantive and normative style of thinking, his new emphases continue to be grounded in arguments pitched at the general theoretical level. One of these involves a particular reading of the nature of post-positivist meta-theory today, and the other, within this, is a determined effort to distinguish (...) a project of ‘cultural sociology’ from ‘sociology of culture’ approaches. I take issue with both of these theoretical moves, showing that they are rhetorically and conceptually flawed, and of a strongly idealist cast. They also run counter to those aspects of Alexander’s outlook that do seem more robustly multidimensional and sociologically promising. (shrink)

The emergence of vibrant research communities of computer scientists in Kenya and Uganda has occurred in the context of neoliberal privatization, commercialization, and transnational capital flows from donors and corporations. We explore how this funding environment configures research culture and research practices, which are conceptualized as two main components of a research community. Data come from a three-year longitudinal study utilizing interview, ethnographic and survey data collected in Nairobi and Kampala. We document how administrators shape research culture by building academic (...) programs and training growing numbers of PhDs, and analyze how this is linked to complicated interactions between political economy, the epistemic nature of computer science and sociocultural factors like entrepreneurial leadership of key actors and distinctive cultures of innovation. In a donor-driven funding environment, research practice involves scientists constructing their own localized research priorities by adopting distinctive professional identities and creatively structuring projects. The neoliberal political economic context thus clearly influenced research communities, but did not debilitate computing research capacity nor leave researchers without any agency to carry out research programs. The cases illustrate how sites of knowledge production in Africa can gain some measure of research autonomy, some degree of global competency in a central arena of scientific and technological activity, and some expression of their regional cultural priorities and aspirations. Furthermore, the cases suggest that social analysts must balance structure with culture, place and agency in their approaches to understanding how funding and political economy shape scientific knowledge. (shrink)

This paper draws a parallel between two contemporary French conceptions of sociology. Each is first considered in terms of the principles and strategies of its sociological method. Through an analogy with Marx's philosophy of social science, critical sociology is shown to make an heuristic use for the analysis of cultures and social structures of the resistance to sociology that the sociologist encounters in the social objects, whereas pragmatic sociology adopts a pluralistic and descriptive strategy towards actions, actors and things. The (...) paper then tries to show how common interests or trading zones could allow both critical and pragmatic sociology to profit from their competitive relation by taking each other as objects of sociological analysis. (shrink)

The essay is a critical examination of the charge of self-refutation, particularly as leveled by orthodoxy-defending philosophers against those maintaining epistemologically unorthodox, especially relativistic or skeptical, views. (It was originally published in *Common Knowledge* in 1993, and reprinted in the journal's 25th anniversary issue.) Beginning with an analysis of its classic illustration in Plato’s Theaetetus as leveled by Socrates against Protagoras’s “Man is the measure..,” the essay considers various aspects of the charge, including its paradigmatic theatrical staging, its frequent pedagogic (...) restaging, its logical and rhetorical structure, its complex emotional and psychological effects, and its apparent cognitive dynamics. After discussion of the comparable structure and dynamics of related self-undoings in myth and drama, the examination of alleged exposures of self-contradiction moves to general observations regarding the recurrent encounter between conviction and skepticism and the question of how best to understand the phenomenon of fundamentally clashing and arguably incommensurable beliefs. These encounters and questions are usefully addressed and illuminated, Smith suggests, by constructivist epistemology, contemporary history and sociology of science, and recent work in cognitive theory. In connection with the logically circular question-begging or self-affirmation commonly involved in demonstrations of the relativist’s self-refutation, Smith gives particular attention to the evidently endemic tendency to cognitive self-stabilization. (shrink)