Although clinical criteria ultimately determine the pathological diagnosis of Alzheimer’s disease, ‘Alzheimer’s’ is also an ordinary sign, falling within a range of other possible signs, values and beliefs that define and are used to interpret dementia and mental diseases. While looking at talk-in-interaction in which two people diagnosed with Alzheimer’s interact with other people, this article tries to show that the way in which both lay and professional people interpret Alzheimer’s signs allows us to shed some light upon the core (...) of the traditional and controversial dichotomy between normal and pathological. The interactions analyzed in this paper show how people oppose biomedical discourse, suggesting that other forms of interpreting aging and forgetfulness are possible. It has opened multiple cartographies or varied spheres of communicability influenced by the signs of Alzheimer’s. (shrink)

This article compares notes on different and new concepts of ‘the Human’, developed both within disciplinary and interdisciplinary academic scientific research and in broader social practices. The main focus is on the shifting relationship between the ‘two cultures’ of the humanities and science in the light of contemporary developments, such as the sophisticated forms of interdisciplinary research that have emerged in the fields of biotechnologies, neural sciences, environmental and climate change research and Information and Communication technologies. These rapid changes affect (...) the very definitions of the human and of human evolution. The question is how and to what extent they have an impact on both the practice of the humanities and on their self-representation. Is humanism challenged or strengthened by these developments? To what extent is anthropocentrism called to task by what is becoming known as posthuman theory? (shrink)

This article provides an overview of the analysis of technological zones. A technological zone can be understood as a space within which differences between technical practices, procedures and forms have been reduced, or common standards have been established. Such technological zones take broadly one of three forms: (1) metrological zones associated with the development of common forms of measurement; (2) infrastructural zones associated with the creation of common connection standards; and (3) zones of qualification which come into being when objects (...) and practices are assessed according to common standards and criteria. The article argues that technological zones can have more or less clear borders, but such borders increasingly do not correspond to the borders of nation-states. Through a discussion of the global oil industry, some of the ways in which the formation of technological zones has become critical to contemporary economic and political life are examined. (shrink)

Kaum ein anderes Thema bündelt aktuell so nachhaltig die Debatte über die Konsequenzen des unlängst ausgerufenen Anthropozäns, wie das des anthropogenen Klimawandels. Nicht nur wird die Umwelt des Menschen unabsehbaren Veränderungen ausgesetzt sein, sondern diese Veränderungen der natürlichen Umwelt sind insbesondere auch humanen Ursprungs. Anthropologie, Ökologie und Ethik werden verschaltet; die zu gewärtigenden Konsequenzen können unabsehbar sein. Damit wird der Klimawandel auch grundlegende anthropologische Folgen haben und sich etwa der epistemische Zuschnitt des Anthropos grundlegend neu definieren. Gerade aber weil Natur (...) hier konsequent humanisiert ist, kann sie auch für die Verfasstheit der Gattung bedrohlich werden und sich gegen das Humanum wenden. (shrink)

I offer a major reassessment of Foucault’s philosophico-historical account of the basic problems of modernity. I revise our understanding of Foucault by countering the influential misinterpretations proffered by his European interlocutors such as Habermas and Derrida. Central to Foucault’s account of modernity was his work on two crucial concept pairs: freedom/power and reason/madness. I argue against the view of Habermas and Derrida that Foucault understood modern power and reason as straightforwardly opposed to modern freedom and madness. I show that Foucault (...) held a much more complex view of these pairs, a view encapsulated in his term ‘reciprocal incompatibility’. By revising our interpretation of Foucault’s work on modernity in this way, we open the way to much more effective deployments of his critical apparatus. (shrink)

This article addresses the need to problematize “cases” in science and technology studies work, as a middle-range theory issue. The focus is not on any one case study per se, but on why case studies exist and endure in STS. Case studies are part of a specific problematization in the field. We therefore explore relations between motivation for the use of cases, their constitution, and ways they can be invoked to make particular kinds of arguments in STS. We set out (...) to examine the case as an object that links together research practices, intellectual debates, and programmatic concerns in our own work. Based on our experiences and on this reflection on the links between cases and questions in STS, we propose a number of casemaking strategies that shift and enrich the deployment of ethnographic cases as an epistemic tool in STS. (shrink)

This article argues that vehicles, roads and routes merit a much more central place in theorizations of migration politics. This argument is developed in terms of three theses. First, the study of migration politics should examine how vehicles feature in the public mediation of migration and border controversies. Second, it is important to analyze vehicles as mobile sites of power and contestation in their own right. Third, an understanding of the materiality of transportation helps to explain how the vehicle can (...) sometimes become a site of strategic political action. These arguments are in turn used to develop a concept of viapolitics as a contribution to literatures on migration, mobilities and power. Viapolitics orients us to see migration from the middle, that is, from the angle of the vehicle and not just the state. It also seeks to connect migration studies to the history of problematizations, cultural types and the mythopoetics of the road. (shrink)

This paper argues that Michel Foucault explicitly rejected the model of critique by which he is often understood—by both his defenders and detractors. Rather than justifying norms that could be said to represent “the people;” judging institutions, norms, and practices accordingly; and creating programs for others to enact, he theorized and practiced an experimental social criticism in which specific intellectuals help people work through “intolerable” situations by multiplying the ways they can think about and act upon them. As Foucault’s work (...) with the prisons in France shows, one way intellectuals can be part of the experimental transformations social bodies carry out upon themselves is through genealogical work describing the ways problems have come to be identified—and can thus be transformed. This account of criticism undercuts the problem of justifying a standpoint of critique that has plagued philosophers and suggests a few concrete means of better aligning theory and practice. (shrink)

This is the second of two special issues, and the articles are grouped according to two themes: The previous, first issue featured articles that shared the theme Technologies and the Political, while this second issue is focused on the theme of Subjectivities. In this second, somewhat expanded, introduction, the “sky’s the limit.” This introduction canvasses various theoretical and conceptual-empricial perspectives that the articles of both issues touch on and further tries to open many doors through which readers are invited to (...) go on their own rather than give readymade answers. This introduction is written not only to give both an overview of some of the most important conceptual, methodological, and empirical contexts that the two special issues evoke but also to create invitations for many further conversations to be had from here on forward by beginning the interrogating and troubling of the intercourse between “science” and “science fiction”: beause all of this has happened before and will happen again. (shrink)

This article discusses the notion of emergent concerned groups and explores how these groups contribute to shaping the relations between technoscience, politics, and economic markets. The first part presents the case of the French Association of patients suffering from muscular dystrophies. This history suggests that under certain conditions, emergent concerned groups are able to impose a new form of articulation between scientific research and political identities by directly linking the issues of research content and results to that of their place (...) in the collective. The second part argues that the evolution of economic markets, combined with that of science and technology, leads to a multiplication of those emergent concerned groups. The study of the conditions under which these emergent groups become legitimate stakeholders as well as the analysis of their impact on market organization and technoscientific institutions are key research topics for the near future. (shrink)

The problem reduced to its lowest terms is whether inquiry can develop in its own ongoing course the logical standards and forms to which further inquiry shall submit.Gilles Deleuze, in his book What Is Philosophy? asks: "What is the best way to follow the great philosophers? Is it to repeat what they said or to do what they did, that is, create concepts for problems that necessarily change?" (Deleuze and Guattari 28). I imagine few in this audience would disagree with (...) that claim. The changing, historically situated, interplay of concepts and problems is a register that those inspired by the work of John Dewey can readily acknowledge as pertinent even if what Dewey meant by each of the terms and what Deleuze meant .. (shrink)

It has been commonplace to equate Foucault’s 1979 series of lectures at the Collège de France with the claim that for neoliberalism, unlike for classical liberalism, the market needs to be artificially constructed. The article expands this claim to its full expression, taking it beyond what otherwise would be a simple divulgation of a basic neoliberal tenet. It zeroes in on Foucault’s own insight: that neoliberal constructivism is not directed at the market as such, but, in principle, at society, arguing (...) that the value of this insight goes beyond the critique of a neoliberal present. The neoliberal rationale rather helps him to reveal a unique historical architecture, a latent approach to the social dissimilar to the one that has long predominated in the human sciences. The inversion of homo œconomicus in neoliberal theory amounted to the unearthing of a ‘social subject of interest’ within civil society. Such a subject, barely recognized by neoliberals who simply instrumentalize it for the sake of the market, demonstrates that the social is not necessarily the natural product of ethical subjects; that society may also need to be constructed. (shrink)

Biomedicine is today transforming the human condition, but how such transformation is to be understood is a matter of debate. I seek to contribute to the debate by focusing on recent developments within a relatively novel subfield of gerontology which is engaged in the bio-molecular and bio-demographic characterization of the processes associated with the development of the organism from birth to death. I argue that these developments aid understanding of the conceptual difficulties confronting neo-Darwinian biological thought and poststructuralist social theory (...) as one decentres the organism and the other the subject. (shrink)

In this article, we argue that contemporary biomedicine is shaped by two, seemingly incommensurable, organizational logics, the ‘regime of truth’ and the ‘regime of hope’. We articulate their features by drawing on debates sparked by the recent clinical trial of a new approach to the treatment of Parkinson’s Disease. We also argue that the ‘self’ is configured in the very same process whereby these two organizational logics interlock and become mutually dependent, so that the ‘self’ might be said to be (...) the effect of a ‘parasitic’ relationship between the regimes of ‘truth’ and ‘hope’. We then bring these two arguments to bear on the contrasting views of the relationship between embodiment and political subjectivity articulated by Michel Foucault and Giorgio Agamben, on the one hand, and Paul Rabinow and Nikolas Rose, on the other hand. (shrink)

The paper asks how certain zones of technical practice or technologies come to matter as "the Technological", a way of construing political change in terms of technical innovation and invention. The social construction of technology (SCOT) established that things mediate social relations, and that social practices are constantly needed to maintain the workability of technologies. It also linked the production, representation and use of contemporary technologies to scientific knowledge. However, it did all this at a certain cost. To understand something (...) as socially constructed implies that it can be positioned on a pre-given social grid. Making this understanding stick risks affronting others with the claim that their position is not singular, only ordinary. It also runs the risk of not having purchase on those aspects of technological relationality that overflow the framing context of the social (Callon et al. 2002). Building on the ground prepared by SCOT and relying on the work of (Stengers 2000) and (Simondon 1964, 1989), the paper discusses how technologies could be understood as relational events within the contemporary political space. Developing an account of technologies centred on relationality, this paper outlines an epistemology and ontology of the anomalies of technological events, and suggests how excess could explain the Technological. (shrink)

Tendencies and efforts have shifted from genome description, DNA mapping, and DNA sequencing to active and profound re-programming, repairing life on genetic and molecular levels in some parts of contemporary life science research. Mirroring and materializing this atmosphere, various life engineering technologies have been used and established in many areas of life sciences in the last decades. A contemporary progressive example of one such technology is DNA editing. Novel developments related to reproductive technologies, particularly embryo editing, prenatal human life engineering, (...) and germline engineering need to be analyzed against the broader social and structural background. The crucial analytical scope for this paper is a specific field: the life-editing technologies used in reproductive medicine and performed experimentally on viable human embryos, particularly CRISPR/cas9 technology. This text argues that germline editing technologies, as a representative part of contemporary biomedicine, are merging ideas of treatment and enhancement to avoid future risks. Using this specific life manipulation of embryos and gametes, the text analyzes these processes within the concept of power over life—biopower and the specific governing rationality that imagines, classifies, and governs contemporary societies. The text specifically focuses on the potential to create, define, and manage future risks and uncertainties related to prenatal life. (shrink)

The elimination of subjectivity through brain research and the replacement of so-called ‘folk psychology’ by a neuroscientifically enlightened worldview and self-conception has been both hoped for and feared. But this cultural revolution is still pending. Based on nine months of fieldwork on the revival of hallucinogen research since the ‘Decade of the Brain,’ this paper examines how subjective experience appears as epistemic object and practical problem in a psychopharmacological laboratory. In the quest for neural correlates of (drug-induced altered states of) (...) consciousness, introspective accounts of test subjects play a crucial role in neuroimaging studies. Firsthand knowledge of the drugs’ flamboyant effects provides researchers with a personal knowledge not communicated in scientific publications, but key to the conduct of their experiments. In many cases, the ‘psychedelic experience’ draws scientists into the field and continues to inspire their self-image and way of life. By exploring these domains the paper points to a persistence of the subjective in contemporary neuropsychopharmacology. (shrink)

Personal genetic information services (PGI) or direct-to-consumer genomics (DTC) presents a convergence of web 2.0 platforms with consumer-oriented genetics that brings together issues of policy and design. The rise of networking over DNA profile and biodata (bionetworking) challenges the common design and HCI notions of interaction, social networking and user needs. It confronts design thinking and HCI with various biopolitical and biosocial issues discussed in STS studies. These interfaces intensify the troubled relationship between what is social and biological, collective and (...) individual, public and private, natural and political, material (embodied) and based on data or discourses. At the same time, this fast evolving convergence of biosciences with social networking transforms scientific practices in a way which demonstrates the importance of design in discussing issues of STS and policy. The notion of cosmopolitics as "collective experimentation" and "progressive composition of the common world" (Bruno Latour) offers a framework for understanding this connection between philosophy, policy and design. Bionetworking interfaces in this sense serve as probes for testing future collectives which transform the notions of human subjects, community and politics. (shrink)

Themes of mastery, domination and power are familiar to any scholar of modern technology. Science is commonly cast as enabling the technological control over both the natural and physical worlds. Indeed, Francis Bacon famously equated scientific knowledge with power itself—stating that ‘knowledge itself is a power’. Bacon’s now ubiquitous phrase—commonly repeated as the banal ‘knowledge is power’—was an attempt to combat three heresies in scriptural interpretation by asserting the conjunction between biblical knowledge and divine power. Opening his critique of the (...) heresies he states: ‘You err, not knowing the scriptures nor the power of God’. In this sense the equation made between knowledge and power is of cosmic significance for Bacon in that knowledge is fundamentally associated with divine power. This image of scientific knowledge, method and rationality is deeply seductive. In this Baconian mode scientific method is irreducibly associated with human mastery over natural systems and the material world. In this image science and technology are defined as a kind of power over the physical world—the power of knowledge, method and the logos over nature, myth and irrationality. In its original Latin sense—ipsa scientia potestas est—the word that translates in English as simply power is a in fact a specific type of power. Potestas is defined as ‘power over’—with particular resonances with political and juridical traditions in Roman law. That is, knowledge is equated not simply with personal capacity. Rather, knowledge produces the power of mastery, domination and coercion... (shrink)

In this article we explore the contribution from social anthropology to the medical ethical debates about the use of informed consent in research, based on blood samples and other forms of tissue. The article springs from a project exploring donors’ motivation for providing blood and healthcare data for genetic research to be executed by a Swedish start-up genomics company. This article is not confined to empirical findings, however, as we suggest that anthropology provides reason to reassess the theoretical understanding of (...) autonomy as generally defined by Beauchamp and Childress. Careful consideration of the trust expressed by donors through the act of donation, furthermore, suggests that there is reason to redirect the ethical scrutiny from informed consent to issues concerning institutional arrangements and social responsibility. In particular, we suggest that an anthropological approach could facilitate a reconsideration of the political implications of using informed consent as a regulatory practice in tissue-based research. (shrink)

Social scientists often lament the fact that philosophically trained ethicists pay limited attention to the insights they generate. This paper presents an overview of tendencies in sociological and anthropological studies of morality, ethics and bioethics, and suggests that a lack in philosophical interest might be related to a tendency among social scientists to employ either a deficit model (social science perspectives accommodate the sense of context that philosophical ethics lacks), a replacement model (social scientists have finally found the “right way” (...) of doing ethics), or a dismissal model (ethics should be abandoned all together as a misconstrued veil of power). Increased awareness of differences in styles of reasoning and objects of research interest might help to overcome the hostility, and an anthropological project is presented as an invitation to a dialogue informed by awareness of such differences. (shrink)

Social scientists often lament the fact that philosophically trained ethicists pay limited attention to the insights they generate. This paper presents an overview of tendencies in sociological and anthropological studies of morality, ethics and bioethics, and suggests that a lack in philosophical interest might be related to a tendency among social scientists to employ either a deficit model (social science perspectives accommodate the sense of context that philosophical ethics lacks), a replacement model (social scientists have finally found the “right way” (...) of doing ethics), or a dismissal model (ethics should be abandoned all together as a misconstrued veil of power). Increased awareness of differences in styles of reasoning and objects of research interest might help to overcome the hostility, and an anthropological project is presented as an invitation to a dialogue informed by awareness of such differences. (shrink)

First, it is clearly a great honor to our society that Paul Rabinow has agreed to present the Coss Dialogue Lecture for 2012. His work in the field of what he has termed "the anthropology of the contemporary" has reached out to otherwise diverse traditions in anthropology and philosophy in order to incorporate their best elements into a novel approach to the logos of anthropos. His case-based studies have focused on the relations between the physical sciences and the human sciences, (...) and especially between the efforts of scientists working in the fields of synthetic biology and the efforts of those working in the fields of the human sciences who take it as their task to evaluate the ethical and other diagnostic .. (shrink)

Cardiovascular diseases present the leading cause of death worldwide. Over the last decade, their preventio has become not only a central medical and public health issue but also a matter of political concern as well as a major market for pharma, nutrition, and exercise. A preventive assemblage has formed that integrates diverse kinds of knowledges, technologies, and actors, from molecular biology to social work, to foster a specific healthy lifestyle. In this article, the authors analyze this preventive assemblage as a (...) heterogeneous engineer, that is, as an attempt to order complex everyday life into an architecture of modernism. This article draws on research conducted as part of the interdisciplinary research cluster ‘‘preventive self’’ bringing together analyses from social anthropology, history, linguistics, sociology of knowledge, and medicine. The authors report here primarily from ethnographic investigations into biomedical research, primary care, and educational practices in kindergartens. The authors conclude that the preventive assemblage largely fails to install any kind of singular order. Instead, it is translated into existing orderings producing heterogeneity of a different nuance. (shrink)

This article analyzes the role of key visual technologies in contemporary media activism in Brazil. Drawing on a range of media formats and sources, it examines how the aesthetic politics of activists in protests that took place in 2013 opened the way for wider sociopolitical change. The forms and practices of the media activists, it is argued, aimed explicitly at producing transformative politics. New media technologies were remediated as a kind of equipment that could generate new relationships and subjectivities, and (...) thereby access to intentionally undetermined futures. (shrink)

In our study of U.S. counterterrorism programs, we found that anthropology needs a mode of analysis that considers security as a form distinct from insecurity, in order to capture the very heterogeneity of security objects, logics and forms of action. This article first presents a genealogy for the anthropology of security, and identifies four main approaches: violence and State terror; military, militarization, and militarism; para-state securitization; and what we submit as “security analytics.” Security analytics moves away from studying security formations, (...) and how much violence or insecurity they yield, to identifying security forms of action, whether or not they are part of the nation-state. As a framework for anthropological inquiry, it is oriented toward capturing how these forms of action work and what types of security they produce. We then illustrate this approach through our fieldwork on counterterrorism in the domains of law enforcement, biomedical research and federal-state counter extremism. In each of our cases, we use security analytics to arrive at a diagnosis of the form of action. The set of conceptual distinctions that we propose as an aid to approaching empirical situations and the study of security is, on another level, a proposal for an approach to anthropology today. We do not expect that the distinctions that aid us will suffice for every situation. Rather, we submit that this work presents a set of specific insights about contemporary U.S. security, and an example of a new approach to anthropological problems. (shrink)

Humphry Osmond wrote to Aldous Huxley in 1956 proposing the term “psychedelic,” coined from two Greek words to mean “mind manifesting.” The scholars, one a psychiatrist and the other a celebrated novelist and philosopher, were exuberant about the potential of drugs for accessing the mind. Huxley favored a phrase from William Blake: -/- If the doors of perception were cleansed everything would appear to man as it is, infinite. -/- He postulated that psychedelics disturbed the “cerebral reducing valve” (1954), and (...) that this was in fact the shared mechanism for regular drug trips, as well as schizophrenic and mystical experiences. If it were the case, the drugs could offer a chemical shortcut to the divine, and a reasonable way to scientifically study mental illness. -/- With such ideas in vogue, the 1950s were heady years, at least for research on psychedelic drugs. More than 750 articles were published on LSD alone. Some studies made use of the drug experience to model schizophrenia, others to develop treatments for alcoholism. And as Nicolas Langlitz explains in Neuropsychedelia: The Revival of Hallucinogen Research Since the Decade of the Brain, the brain as filter – the idea of gates or doors (which, yes, also gave name to the band) – would go on to serve as a significant shared conceptual matrix for psychopharmacologic research, from experimental psychosis to experimental mysticism (10). (shrink)

This chapter examines global policing as it takes shape through the work of Interpol, the International Criminal Police Organization. Global policing emerges in the legal, political and technological amalgam through which transnational police cooperation is carried out, and includes the police practices inflected and made possible by this phenomenon. Interpol’s role is predominantly in the circulation of information, through which it enters into relationships and provides services that affect aspects of governance, from the local to national, regional and global. The (...) chapter describes this assemblage as a noteworthy experiment in developing what McKeon called a frame for common action. Drawing on Interpol publications, news stories, interviews with staff, and fieldwork at the General Secretariat in Lyon, France, the history, institutional structure, and daily practices are described. Three cases are analyzed, concerning Red Notices, national sovereignty, and terrorism, in order to explore some of the problems arising in Interpol’s political and technical operating arrangements. In conclusion, international and global policing are compared schematically, together with Interpol’s attempts to give institutional and procedural direction to the still-evolving form of global policing. (shrink)

A core historical narrative about anthropological knowledge is that it is created in relations with others, with fieldwork seen as ‘a series of apprenticeships’ whose success is determined by the quality of those relations. An ethnographer connects with the conditions of those studied in ‘circulating exchange’; but on leaving the field a degree of closure is needed to formulate and communicate anthropological knowledge. These obligations and requirements in the creation of knowledge entail attachment and detachment, carrying the seeds of betrayal (...) that can compromise that knowledge. Each epistemological enquiry has its own core ethical imperatives, but as long as knowledge posits a knower, ‘the self of the knower will be at epistemological issue’. In discussing the ethics of knowledge creation I consider the following questions, among others: To what extent is the creation of a particular kind of ethical and epistemic person required for knowledge? How can ethnography produce knowledge about others without betraying them? Can relations of knowledge exchange confer or withhold ‘rights to speak’? Is it possible that unethical relations may destroy or hold up the unfolding of knowledge? And are there circumstances in which it is unethical to disclose knowledge? (shrink)