Philosophers have debated at length the epistemological status of scientific thought experiments. I contend that the literature on this topic still lacks a common conceptual framework, a lacuna that produces radical disagreement among the participants in this debate. To remedy this problem, I suggest focusing on the distinction between the internal and the external validity of an experiment, which is also crucial for thought experiments. I then develop an account of both kinds of validity in the context of thought experiments. (...) I show that we can naturally conceptualise internal validity in terms of games of make-believe. Then, I argue that external validity is best defined as accurate representation of a target system. Finally, I turn back to the current debate on thought experiments and show that my diarchic account provides a general framework that can be shared by the competing philosophical views, as well as a fruitful guide for their reconciliation. (shrink)

This dissertation is about human knowledge of reality. In particular, it argues that scientific knowledge is bounded by historically available instruments and theories; nevertheless, the use of several independent instruments and theories can provide access to the persistent potentialities of reality. The replicability of scientific observations and experiments allows us to obtain explorable evidence of robust entities and properties. The dissertation includes seven chapters. It also studies three cases – namely, Higgs bosons and hypothetical Ϝ-particles (section 2.4), the Ptolemaic and (...) Kepler model of the planets (section 6.7), and the special theory of relativity (chapter 7). -/- Chapter 1 is the introduction of the dissertation. Chapter 2 clarifies the notion of the real on the basis of two concepts: persistence and resistance. These concepts enable me to explain my ontological belief in the real potentialities of human-independent things and the implications of this view for the perceptual and epistemological levels of discussion. On the basis of the concept of “overlapping perspectives”, chapter 3 argues that entity realism and perspectivism are complementary. That is, an entity that manifests itself through several experimental/observational methods is something real, but our knowledge of its nature is perspectival. Critically studying the recent views of entity realism, chapter 4 extends the discussion of entity realism and provides a criterion for the reality of property tokens. Chapter 5, in contrast, develops the perspectival aspects of my view on the basis of the phenomenological-hermeneutical approaches to the philosophy of science. This chapter also elaborates my view of empirical evidence, as briefly expressed in sections 2.5 and 4.5. Chapter 6 concerns diachronic theoretical perspectives. It first explains my view of progress, according to which current perspectives are broader than past ones. Second, it argues that the successful explanations and predictions of abandoned theories can be accounted for from our currently acceptable perspectives. The case study of Ptolemaic astronomy supports the argument of this chapter. Chapter 7 serves as the conclusion of the dissertation by applying the central themes of the previous chapters to the case study of special relativity theory. I interpret frame-dependent properties, such as length and time duration, and the constancy of the speed of light according to realist perspectivism. (shrink)

Discussions of reproducibility are casting doubts on the credibility of experimental outcomes in the life sciences. Although experimental evolution is not typically included in these discussions, this field is also subject to low reproducibility, partly because of the inherent contingencies affecting the evolutionary process. A received view in experimental studies more generally is that standardization (i.e., rigorous homogenization of experimental conditions) is a solution to some issues of significance and internal validity. However, this solution hides several difficulties, including a reduction (...) of external validity and reproducibility. After explaining the meaning of these two notions in the context of experimental evolution, we import from the fields of animal research and ecology and suggests that systematic heterogenization of experimental factors could prove a promising alternative. We also incorporate into our analysis some philosophical reflections on the nature and diversity of research objectives in experimental evolution. (shrink)

John D. Norton is responsible for a number of influential views in contemporary philosophy of science. This paper will discuss two of them. The material theory of induction claims that inductive arguments are ultimately justified by their material features, not their formal features. Thus, while a deductive argument can be valid irrespective of the content of the propositions that make up the argument, an inductive argument about, say, apples, will be justified (or not) depending on facts about apples. The argument (...) view of thought experiments claims that thought experiments are arguments, and that they function epistemically however arguments do. These two views have generated a great deal of discussion, although there hasn’t been much written about their combination. I argue that despite some interesting harmonies, there is a serious tension between them. I consider several options for easing this tension, before suggesting a set of changes to the argument view that I take to be consistent with Norton’s fundamental philosophical commitments, and which retain what seems intuitively correct about the argument view. These changes require that we move away from a unitary epistemology of thought experiments and towards a more pluralist position. (shrink)

Replicability is widely taken to ground the epistemic authority of science. However, in recent years, important published findings in the social, behavioral, and biomedical sciences have failed to replicate, suggesting that these fields are facing a “replicability crisis.” For philosophers, the crisis should not be taken as bad news but as an opportunity to do work on several fronts, including conceptual analysis, history and philosophy of science, research ethics, and social epistemology. This article introduces philosophers to these discussions. First, I (...) discuss precedents and evidence for the crisis. Second, I discuss methodological, statistical, and social-structural factors that have contributed to the crisis. Third, I focus on the philosophical issues raised by the crisis. Finally, I discuss proposed solutions and highlight the gaps that philosophers could focus on. (shrink)

It is often said that computer simulations generate new knowledge about the empirical world in the same way experiments do. My aim is to make sense of such a claim. I first show that the similarities between computer simulations and experiments do not allow them to generate new knowledge but invite the simulationist to interact with simulations in an experimental manner. I contend that, nevertheless, computer simulations and experiments yield new knowledge under the same epistemic circumstances, independently of any features (...) they may share. (shrink)

Sometimes we learn through the use of imagination. The epistemology of imagination asks how this is possible. One barrier to progress on this question has been a lack of agreement on how to characterize imagination; for example, is imagination a mental state, ability, character trait, or cognitive process? This paper argues that we should characterize imagination as a cognitive ability, exercises of which are cognitive processes. Following dual process theories of cognition developed in cognitive science, the set of imaginative processes (...) is then divided into two kinds: one that is unconscious, uncontrolled, and effortless, and another that is conscious, controlled, and effortful. This paper outlines the different epistemological strengths and weaknesses of the two kinds of imaginative process, and argues that a dual process model of imagination helpfully resolves or clarifies issues in the epistemology of imagination and the closely related epistemology of thought experiments. (shrink)

This is the introduction to the Routledge Companion to Thought Experiments.

What role does the imagination play in scientific progress? After examining several studies in cognitive science, I argue that one thing the imagination does is help to increase scientific understanding, which is itself indispensable for scientific progress. Then, I sketch a transcendental justification of the role of imagination in this process.

In this paper, the different theories about science and technology relationships are analyzed. All of them have some virtues, but also one main defect: these theories do not take into account other well-founded possible relationships. The origin of this problem is the narrow view about science and technology. In this paper another characterization about technology based on Ronald Giere’s perspective is suggested. In the light of this new description, six different relationships between science and technology arise. Some of these relations (...) had been explained in the before analyzed theories, but others emerge from the new portrayal. (shrink)

I would like to assume that Reichenbach's distinction of Justification and Discovery lives on, and to seek arguments in his texts that would justify their relevance in this field. The persuasive force of these arguments transcends the contingent circumstances apart from which their genesis and local transmission cannot be made understandable. I shall begin by characterizing the context distinction as employed by Reichenbach in "Experience and Prediction" to differentiate between epistemology and science (1). Following Thomas Nickles and Kevin T. Kelly, (...) one can distinguish two meanings of the context distinction in Reichenbach's work. One meaning, which is primarily to be found in the earlier writings, conceives of scientific discoveries as potential objects of epistemological justification. The other meaning, typical for the later writings, removes scientific discoveries from the possible domain of epistemology. The genesis of both meanings, which demonstrates the complexity of the relationships obtaining between epistemology and science, can be made understandable by appealing to the historical context (2). Both meanings present Reichenbach with the task of establishing the autonomy of epistemology through the justification of induction. Finally, I shall expound this justification and address some of its elements of rationality characterizing philosophy of science(3). (shrink)

Hermeneutics, or interpretation, is concerned with the generation, transmission, and acceptance of meaning within the lifeworld, and was the original method of the human sciences stemming, from F. Schleiermacher and W. Dilthey. The `hermeneutic philosophy' refers mostly to Heidegger. This paper addresses natural science from the perspective of Heidegger's analysis of meaning and interpretation. Its purpose is to incorporate into the philosophy of science those aspects of historicality, culture, and tradition that are absent from the traditional analysis of theory and (...) explanation, to re-orient the current discussion about scientific realism around the hermeneutics of meaning and truth in science, and to establish some relationship between the current philosophy of natural science and hermeneutical philosophy. The paper has particular relevance to the history and social studies of science and technology. (shrink)

Starting from the sixties of the past century theory change has become a main concern of philosophy of science. Two of the best known formal accounts of theory change are the post-Popperian theories of verisimilitude (PPV for short) and the AGM theory of belief change (AGM for short). In this paper, we will investigate the conceptual relations between PPV and AGM and, in particular, we will ask whether the AGM rules for theory change are effective means for approaching the truth, (...) i.e., for achieving the cognitive aim of science pointed out by PPV. First, the key ideas of PPV and AGM and their application to a particular kind of propositional theories - the so called "conjunctive propositions" - will be illustrated. Afterwards, we will prove that, as far as conjunctive propositions are concerned, AGM belief change is an effective tool for approaching the truth. (shrink)

A central question in constructivist studies of science is how the analyst should deal with the material objects handled by scientific practitioners in laboratories. Representatives of ‘radical constructivism’ such as Knorr-Cetina and Latour have gone furthest in exploring the role of these ‘non-humans’ but have also maneuvered themselves in untenable positions due to a fatal conflation of different meanings of the term ‘construction’. The epistemological and ontological commitments of ‘moderate constructivism’ especially of the Strong Program defended by Barnes and Bloor, (...) are more suitable for dealing with the task at hand. While radical constructivists treat the domains of nature and human society as largely coterminous, an alternative ontology stresses that natural reality is never fully absorbed into the world of culture but only interacts with the latter at localizable interfaces such as practices and artifacts. This perspective promises a more relaxed relationship with current forms of scientific realism. (shrink)

Two goals - improving replicability and accountability of Machine Learning research respectively, have accrued much attention from the AI ethics and the Machine Learning community. Despite sharing the measures of improving transparency, the two goals are discussed in different registers - replicability registers with scientific reasoning whereas accountability registers with ethical reasoning. Given the existing challenge of the Responsibility Gap - holding Machine Learning scientists accountable for Machine Learning harms due to them being far from sites of application, this paper (...) posits that reconceptualizing replicability can help bridge the gap. Through a shift from model performance replicability to claim replicability, Machine Learning scientists can be held accountable for producing non-replicable claims that are prone to eliciting harm due to misuse and misinterpretation. In this paper, I make the following contributions. First, I define and distinguish two forms of replicability for ML research that can aid constructive conversations around replicability. Second, I formulate an argument for claim-replicability's advantage over model performance replicability in justifying assigning accountability to Machine Learning scientists for producing non-replicable claims and show how it enacts a sense of responsibility that is actionable. In addition, I characterize the implementation of claim replicability as more of a social project than a technical one by discussing its competing epistemological principles, practical implications on Circulating Reference, Interpretative Labor, and research communication. (shrink)

Relying on the notion of “overlapping perspectives,” this paper argues that entity realism and perspectivism are complementary. According to entity realism, it is justified to maintain a positive attitude toward the existence of unobservable entities with which multiple experimental interactions are possible. Perspectivism also explains that our beliefs about these entities are bounded by historically contingent theoretical and instrumental perspectives. The argument of the paper is developed through a discussion of Ronald Giere’s versions of realism: entity realism, constructive realism, and (...) perspectival realism. (shrink)

While engineering ethics usually addresses the responsibility of engineers in rare cases of whistle blowing, the authors broach the question to what extent engineers can be held responsible in normal practice. For this purpose, they define the conditions under which individuals can be imputable as they prevail in ethics and common sense. From outcomes of science and technology studies research, the authors conclude that these conditions are seldom met in modern technoscientific research practice. By examining such practice in a case (...) study and comparing the results with perceptions of engineers on social responsibility as expressed in interviews, the authors are able to demonstrate that a change in structural characteristics of this practice, such as funding rules, stimulates engineers to attune the inner politics of science to wider societal policies and concerns, and it helps them to overcome the shifting of social responsibility to others as a consequence of the lack of agency they usually perceive. (shrink)

A number of recent discussions comparing computer simulation and traditional experimentation have focused on the significance of “materiality.” I challenge several claims emerging from this work and suggest that computer simulation studies are material experiments in a straightforward sense. After discussing some of the implications of this material status for the epistemology of computer simulation, I consider the extent to which materiality (in a particular sense) is important when it comes to making justified inferences about target systems on the basis (...) of experimental results. (shrink)

In the article two viewpoints on the mind’s influence on perception are considered. One of them was developed on the assumption that perception is a nonproblematic source of knowledge about the world, which is free from mind’s influence— perception as a mirror-image. Another viewpoint is perception as action, i.e. active search and gathering the relevant information, its processing and evaluation. First viewpoint has dominated in philosophy for a long time, the second one has been developing in psychology from the 80th (...) of the 20th century. The aim of the paper is to examine some philosophically significant corollaries from both positions concerning objectiveness, epistemological status of an observation, truth, meaning of name. Analysis showed that perception as action is non-compatible with many traditional concepts, and it goes both against empiricism and against realism as it involves some critical arguments, e.g. theory ladenness of observations, underdetermination of theory by facts, the historical development of a scientific fact. (shrink)

Thus far, the philosophical study of patenting has primarily focused on sociopolitical, legal, and ethical issues, such as the moral justifiability of patenting living organisms or the nature of (intellectual) property. In addition, however, the theory and practice of patenting entails many important problems that can be fruitfully studied from the perspective of the philosophy of science and technology. The principal aim of this article is to substantiate the latter claim. For this purpose, I first provide a concise review of (...) the main features of the theory and practice of the patenting of scientific and technological inventions. Second, I discuss several philosophical issues implied by these features and explore the possible contributions of the philosophy of science and technology to the clarification, or resolution, of these issues. The seven features discussed are: patents as commercial monopolies on scientific and technological inventions, the contrast between natural and non-natural subject matter, the distinction between inventions and discoveries, the reproducibility of inventions, the question of the sameness of two inventions, the distinction between the invented and the protected object, and the contrast between material objects versus concepts and theories. The article concludes with some observations on the problems and prospects of the philosophical study of the theory and practice of patenting scientific and technological inventions. (shrink)

The last forty years have produced a dramatic reversal in leading accounts of science. Once thought necessary to (explain) scientific progress, a rigid method of science is now widely considered impossible. Study of products yields to study of processes and practices, .unity gives way to diversity, generality to particularity, logic to luck, and final justification to heuristic scaffolding. I sketch the story, from Bacon and Descartes to the present, of the decline and fall of traditional scientific method, conceived as The (...) Central Planning Bureau for Science or as Rationality Czar. I defend a deflationary account of method and of rational judgment,. with emphasis on heuristic appraisal and cognitive economy. (shrink)

Structural realists of nearly all stripes endorse the structural continuity claim. Roughly speaking, this is the claim that the structure of successful scientific theories survives theory change because it has latched on to the structure of the world. In this paper I elaborate, elucidate and modify the structural continuity claim and its associated argument. I do so without presupposing a particular conception of structure that favours this or that kind of structural realism. Instead I focus on how structural realists can (...) best account for the neutrally formulated historical facts. The result, I hope, crystallises some of the shared commitments, desiderata and limits of structural realists. (shrink)

This article examines the debate about the normative relevance of social constructivism, arguing that the criticisms of Winner, Radder, and others are fundamentally accurate. The article argues that a combination of Radder's notion of nonlocal values and Martin's concern for deliberative interventions may offer a theoretical exit from the normative irrelevance that marks constructivism. The article goes on to suggest that theoretical and praxeological developments in two other literatures, participatory public policy analysis and deliberative democracy, may provide fruitful initiatives for (...) constructivist scholars eager to address normative concerns. The article next reviews a range of problems facing deliberative and participatory practices and suggests ways in which constructivist insights might help to advance deliberative theory. (shrink)

This article outlines a philosophy of science in practice that focuses on the engineering sciences. A methodological issue is that these practices seem to be divided by two different styles of scientific reasoning, namely, causal-mechanistic and mathematical reasoning. These styles are philosophically characterized by what Kuhn called ?disciplinary matrices?. Due to distinct metaphysical background pictures and/or distinct ideas of what counts as intelligible, they entail distinct ideas of the character of phenomena and what counts as a scientific explanation. It is (...) argued that the two styles cannot be reduced to each other. At the same time, although they are incompatible, they must not be regarded as competing. Instead, they produce different kinds of epistemic results, which serve different kinds of epistemic functions. Moreover, some scientific breakthroughs essentially result from relating them. This view of complementary styles of scientific reasoning is supported by pluralism about metaphysical background pictures. (shrink)

This paper proposes a framework for a critical philosophy of technology by discussing its practical, theoretical, empirical, normative and political dimensions. I put forward a general account of technology, which includes both similarities and dissimilarities to Andrew Feenberg's instrumentalization theory. This account characterizes a technology as a "(type of) artefactual, functional system with a certain degree of stability and reproducibility". A discussion of how such technologies may be realized discloses five different levels at which alternative choices might be made. On (...) this basis, I argue that a critical philosophy of technology should analyse and assess the choices that have, and have not, been made in actual practice, and contribute to social experiments that aim at more democratic and more desirable alternatives. (shrink)

The doctrine of eliminative materialism holds that belief-desire psychology is massively referentially disconnected. We claim, however, that it is not at all obvious what it means to be referentially (dis)connected. The two major accounts of reference both lead to serious difficulties for eliminativism: it seems that elimination is either impossible or omnipresent. We explore the idea that reference fixation is a much more local, partial, and context-dependent process than was supposed by the classical accounts. This pragmatic view suggests that elimination (...) is not the prime model for understanding the complex relations between the mind and brain sciences, and that we have little ground for concluding that in general psychological kinds do not exist. We suggest that reference changes are better seen as continuous rather than completely eliminative. (shrink)

Structural realism has various diverse manifestations. One of the things that structural realists of all stripes have in common is their endorsement of what I call 'the structural continuity claim'. Roughly, this is the idea that the structure of successful scientific theories survives theory change because it has latched on to the structure of the world. In this talk I elaborate, elucidate and modify the structural continuity claim and its associated argument. I do so without presupposing a particular conception of (...) structure that favours this or that kind of structural realism but instead by concentrating on neutrally formulated historical facts. The result, I hope, throws light on what a structural realist must do to evidentially benefit from the historical record of science. The implicit argument underwriting the structural continuity claim can be reconstructed as follows: Premise (1) Only structural elements of predictively and explanatorily successful scientific theories have been (and will be) preserved through theory change. Premise (2): Preservation of an element implies or at least is good evidence for its (approximate) truth. Premise (3): Non-preservation of an element implies or at least is good evidence for its falsity. Conclusion: It is probably the case that only structural elements are (approximately) true. In this summary I restrict my comments to the first premise. Several points can be raised with respect to it. First, not all structures are created equal. Some play no active role in the predictive and explanatory success of a theory because they do not correspond to any structure in the world. Their non-preservation would therefore not encumber the structural realist. Traditional scientific realists have long employed a distinction between essential and idle posits to weed out those elements of theories that played no substantial role in their predictive and explanatory success.. (shrink)

In this article, I put forward a basic philosophical claim: empirical scientific knowledge, that is, knowledge generated in experimental and observational practices, presupposes real causation. My discussion exploits two core notions from the philosophical analysis of scientific experimentation and observation: the aim of realizing object-apparatus correlations and the required control of the relevant interactions between environment and experimental or observational system. The conclusion is that, without the notion of real causation, acquiring epistemically sound empirical knowledge is impossible. Several empiricist objections (...) to this conclusion are discussed and refuted. As a consequence, empiricism faces an unsolvable dilemma: either it cannot account for empirical knowledge or it should accept the existence of unobservable but real causal interactions. (shrink)

A heated debate surrounds the significance of reproducibility as an indicator for research quality and reliability, with many commentators linking a "crisis of reproducibility" to the rise of fraudulent, careless and unreliable practices of knowledge production. Through the analysis of discourse and practices across research fields, I point out that reproducibility is not only interpreted in different ways, but also serves a variety of epistemic functions depending on the research at hand. Given such variation, I argue that the uncritical pursuit (...) of reproducibility as an overarching epistemic value is misleading and potentially damaging to scientific advancement. Requirements for reproducibility, however they are interpreted, are one of many available means to secure reliable research outcomes. Furthermore, there are cases where the focus on enhancing reproducibility turns out not to foster high-quality research. Scientific communities and Open Science advocates should learn from inferential reasoning from irreproducible data, and promote incentives for all researchers to explicitly and publicly discuss their methodological commitments, the ways in which they learn from mistakes and problems in everyday practice, and the strategies they use to choose which research component of any project needs to be preserved in the long term, and how. (shrink)

The main question of this article is given by its title: how inclusive is European philosophy of science? Phrased in this way, the question presupposes that, as a mature discipline, philosophy of science should provide an inclusive account of its subject area. I first provide an explanation of the notion of an inclusive philosophy of science. This notion of an inclusive philosophy of science is specified by discussing three general topics that seem to be missing from, or are quite marginal (...) in, restricted philosophy of science. These topics are the philosophy of historical inquiry, the role of technology in science, and the socio-political and moral dimensions of science. On this basis, I address the question whether European philosophy of science qualifies as more inclusive as compared with Anglo-American philosophy of science. (shrink)

Surprisingly, modified versions of the confirmation theory (Carnap and Hempel) and truth approximation theory (Popper) turn out to be smoothly sythesizable. The glue between the two appears to be the instrumentalist methodology, rather than that of the falsificationalist. The instrumentalist methodology, used in the separate, comparative evaluation of theories in terms of their successes and problems (hence, even if already falsified), provides in theory and practice the straight road to short-term empirical progress in science ( à la Laudan). It is (...) also argued that such progress is also functional for all kinds of truth approximation: observational, referential, and theoretical. This sheds new light on the long-term dynamics of science and hence on the relation between the main epistemological positions, viz., instrumentalism (Toulmin, Laudan), constructive empiricism (Van Fraassen), referential realism (Hacking, Cartwright), and theory realism of a non-essentialist nature (constructive realism à la Popper). Readership: Open minded philosophers and scientists. The book explains and justifies the scientist's intuition that the debate among philosophers about instrumentalism and realism has almost no practical consequences. (shrink)

Laboratory experimentation was once considered impossible or irrelevant in economics. Recently, however, economic science has gone through a real ‘laboratory revolution’, and experimental economics is now a most lively subfield of the discipline. The methodological advantages and disadvantages of controlled experimentation constitute the main subject of this thesis. After a survey of the literature on experiments in philosophy and economics, the problem of testing normative theories of rationality is tackled. This philosophical issue was at the centre of a famous controversy (...) in decision theory, during which a methodology of normative falsification was first articulated and used to assess experimental results. In the third chapter, the methodological advantages of controlled experimentation are illustrated and discussed with examples taken from the experiments on the so-called ‘preference reversal’ phenomenon. Laboratory testing allows to establish with a high degree of certainty that certain phenomena lie behind the experimental data, by means of independent testing, elimination of alternative hypotheses, and the use of different instruments of observation. The fourth chapter is devoted to a conceptual analysis of the problem of ‘parallelism’. This is the problem of inferring from the occurrence of a phenomenon in the laboratory, to its instantiation also in non-laboratory environments. Experimental economists have discussed parallelism at length, and their views are presented and criticised. Eventually, it is argued that parallelism is a factual matter and as such can only be established on empirical grounds. The fifth chapter provides an example of how one can argue for parallelism, focusing on the case of experimentation on the ‘winner’s curse’ phenomenon. The role of experiments as ‘mediators’ between theoretical models and their target domain of application is illustrated, and the structure of parallelism arguments analysed in detail. Finally, in the last chapter, economic experiments are compared to simulations, in order to highlight their specific characteristics. (shrink)

Conditions for philosophy of science in the Netherlands are not optimal. The climate of opinion in Dutch philosophy is unsympathetic to the sciences, partly because of the influence of theology. Dutch universities offer no taught graduate programmes in philosophy of science, which would provide an entry route for science graduates. A great deal of Dutch research in philosophy of science is affected by an exegetical attitude, which fosters the interpretation and evaluation of other writers rather than the development of original (...) theories. Doctoral candidates in particular should be trained to greater originality and assertiveness. Nonetheless, much good research in philosophy of science is conducted in the Netherlands, both in philosophy faculties and in institutes dedicated to the foundations of the special sciences. Distinguished work is done also in the neighbouring disciplines of logic, history of science, and social studies of science. (shrink)

Taking into account how much modern medicine is a function of—and at the same time has a function in—science and technology, it is hardly surprising that both the approach of science studies and the idea of the social and cultural construction of health, disease, and bodies overlap, generally and specifically, in the realm of the novel field of MEDICINE STUDIES. The work already done in science and technology studies as well as in social studies of medicine, together with the rich (...) tradition of medical history and philosophy of medicine, may be considered a solid base and a good vantage point for further analysis. By exploring the shifts of knowledge production in medicine we may be able to see the driving forces behind the ongoing development of medicine and the associated transformation of its social functions in a new light. Based on historiographical reconstructions we may come up with a much more broadly contextualized understanding of the ways in which science, technology, medicine and society interact and in what regard their mutual interdependencies have been undergoing profound changes for a number of decades. By tracing the channels through which key concepts defining the relationship of medicine and its social context are negotiated, we may further explore how our notions of health, disease, and humanity are continuously morphing alongside the incessant transformations of medicine. This editorial explores the aims and scope of MEDICINE STUDIES as a truly transdisciplinary endeavor. (shrink)

On the relation between experiment and thought experiment in the natural sciences. To understand the reciprocal autonomy and complementarity of thought and real experiment, it is necessary to distinguish between a ‘positive’ (empirical or formal) and a transcendental perspective. Empirically and formally, real and thought experiments are indistinguishable. However, from a reflexive-transcendental viewpoint thought experiment is at the same time irreducible and complementary to real experiment. This is due to the fact that the hypothetical-anticipatory moment is in principle irreducible to (...) physical reality—even though it refers to physical reality and is bound with the empirical use of our understanding. The presence of counterfactuals is the condition of the possibility for thought experiments to become in principle real ones, by means of a series of technical realisations that gradually approximate the idealisations that they contain. (shrink)