University of North Carolina at Greensboro Most approaches to the philosophy of the natural and social sciences are basedon completed scientific investigations. However, there are many importantcases in science in which testing is incomplete. These cases are termed suspendedtrials and are particularly significant in biomedical and allied health fields. Initially,the authors' interest in suspended trials was piqued by a controversialmethod for assisting autistic children known as facilitated communication. Thisarticle examines facilitated communication and other examples of suspendedtrials from the perspective of (...) an economics of science and game theory. Themodel is consistent with recent evolutionary approaches to the philosophy ofthe natural and social sciences and with recent contributions to an economicunderstanding of science. Key Words: clinical trials • innovative therapies • economics of science • suspended trials • facilitated communication • economics of clinical research. (shrink)

The paper locates, appreciates, and extends several dimensions of Simon’s work in the direction of more recent contributions by people such as Gigerenzer and Dennett. The author’s “crowbar model of method” is compared to Simon’s scissors metaphor. Against an evolutionary background, both support a pragmatic rather than strong realist approach to theoretically deep and complex problems. The importance of implicit knowledge is emphasized, for humans, as well as nonhuman animals. Although Simon was a realist in some respects, his work on (...) bounded rationality, satisficing, problem solving, heuristics, models, and scientific discovery mark him as a pragmatist. Indeed, he should be regarded as one of the great American pragmatists, alongside Peirce, James, Dewey, and a few others. (shrink)

The article remarks that, despite what many relativists claim, realism still is an arguable and defendable position. Realism is for sure quite an unpopular stance today, but the standard arguments against it are by no means conclusive. If one asks what difference is made to our knowledge claims if we accept the existence of an extra-conceptual world, the answer is the following: such recognition is likely to undermine the largely diffused anthropocentric stance which identifies reality with our knowledge of it.

Just as political theorists have long argued that democracy is viable only in communities of certain sizes and shapes, perhaps epistemologists should also entertain the idea that knowledge is possible only within certain social parameters-ones which today's world may have exceeded. This is what I mean by the "postepistemic" society. I understand an "epistemic society" in Popperian terms as an environment that fosters the spirit of conjectures and refutations. After castigating analytic philosophers for their failure to see this point, I (...) show how Rousseau and Feyerabend occupy analogous positions as critics of, respectively, the nation-state and Big Science. Rather than endorsing the disestablishment of the state, however, I offer a proposal for reinjecting the critical attitude into Big Science. It involves heightening the sporting character of scientific disputes, perhaps even to the point of enabling the public to bet on their outcomes. (shrink)

Advocates of the self-corrective thesis argue that scientific method will refute false theories and find closer approximations to the truth in the long run. I discuss a contemporary interpretation of this thesis in terms of frequentist statistics in the context of the behavioral sciences. First, I identify experimental replications and systematic aggregation of evidence (meta-analysis) as the self-corrective mechanism. Then, I present a computer simulation study of scientific communities that implement this mechanism to argue that frequentist statistics may converge upon (...) a correct estimate or not depending on the social structure of the community that uses it. Based on this study, I argue that methodological explanations of the “replicability crisis” in psychology are limited and propose an alternative explanation in terms of biases. Finally, I conclude suggesting that scientific self-correction should be understood as an interaction effect between inference methods and social structures. (shrink)

Nicholas Rescher embraces a more objectivist, realist, analytic pragmatism than the pragmatism which has been in vogue in the last two decades. He rejects any pragmatism for which there is no truth, reality, or objectivity but only conversations or solidarity within this or that vocabulary. Rescher has argued that pragmatism, far from being anti-realist, provides the only good argument for realism and for our ability to operate the causal model of inquiry about the real world. I examine this kind of (...) pragmatist argument, point out its pitfalls, and argue that Rescher avoids them. (shrink)

In this paper I argue for a place for logic inscientific methodology, at the same level asthat of computational and historicalapproaches. While it is well known that a awhole generation of philosophers dismissedLogical Positivism (not just for the logicthough), there are at least two reasons toreconsider logical approaches in the philosophyof science. On the one hand, the presentsituation in logical research has gone farbeyond the formal developments that deductivelogic reached last century, and new researchincludes the formalization of several othertypes of (...) reasoning, like induction andabduction. On the other hand, we call for abalanced Philosophy of Science, one inwhich both methods, the formal and thehistorical may be complementary, togetherproviding a pluralistic view of science, inwhich no method is the predominant one. (shrink)

Framing systematics as a field consistent with scientific inquiry entails that inferences of phylogenetic hypotheses have the goal of producing accounts of past causal events that explain differentially shared characters among organisms. Linking observations of characters to inferences occurs by way of why-questions implied by data matrices. Because of their form, why-questions require the use of common-cause theories. Such theories in phylogenetic inferences include natural selection and genetic drift. Selection or drift can explain ‘morphological’ characters but selection cannot be causally (...) applied to sequences since fitness differences cannot be directly associated with individual nucleotides or amino acids. The relation of selection to sequence data is by way of downward or top-down causation from those phenotypes upon which selection occurs. The application of phylogenetic inference to explain sequence data is thus restricted to instances where drift is the relevant theory; those nucleotides or amino acids that can be explained via downward causation are precluded from inclusion in the data matrix. The restrictions on the inclusion of sequence data in phylogenetic inferences equally apply to species hypotheses, precluding the more restrictive approach known as DNA barcoding. Not being able to discern drift and selection as relevant causal mechanisms can severely constrain the inclusion and explanations of sequence data. Implications of such exclusion are discussed in relation to the requirement of total evidence. (shrink)

Thesis (Ph. D.)--University of Hawaii at Manoa, 1991.