In their paper from 1981, Milner and Sauer conjectured that for any poset P,≤, if , then P must contain an antichain of cardinality κ. The conjecture is consistent and known to follow from GCH-type assumptions. We prove that the conjecture has large cardinals consistency strength in the sense that its negation implies, for example, the existence of a measurable cardinal in an inner model. We also prove that the conjecture follows from Martin’s Maximum and holds for all singular λ (...) above the first strongly compact cardinal. (shrink)