Jaegwon Kim has developed an argument that interactionist dualists cannot account for the causal relations between minds and brains. This paper develops a closely related argument that focuses instead on the causal relations between minds and neurons. While there are several promising responses to Kim’s argument, their plausibility relies on a relatively simple understanding of mind–brain relations. Once we shift our focus to neurons, these responses lose their appeal. The problem is that even if mind–brain causal pairing can be explained (...) at no great theoretical cost, the complex interactions non-physical minds would need to have with neurons cannot. (shrink)

Interactionists hold that minds are non-physical objects that interact with brains. The neural discernment problem for interactionism is that of explaining how non-physical minds produce behavior and cognition by exercising different causal powers over physiologically similar neurons. This paper sharpens the neural discernment problem and proposes two interactionist models of mind-brain interaction that solve it. One model avoids overdetermination while the other respects the causal closure of the physical domain.