We present a method that generates two-sided sequent calculi for four-valued logics like "first degree entailment" (FDE). (We say that a logic is FDE-like if it has finitely many operators of finite arity, including negation, and if all of its operators are truth-functional over the four truth-values 'none', 'false', 'true', and 'both', where 'true' and 'both' are designated.) First, we show that for every n-ary operator * every truth table entry f*(x1,...,xn) = y can be characterized in terms of a (...) pair of sequent rules. Secondly, we use these sequent rules to build sequent calculi and prove their completeness. With the help of two simplification procedures we then show that the 2⋅4^n sequent rules that characterize an n-ary operator can be systematically reduced to at most four sequent rules. Thirdly, we use our method to investigate the proof-theoretical consequences of including intuitive truth-functional implications in FDE-like logics. (shrink)