We consider momentum operators on intrinsically curved manifolds. Given that the momentum operators are Killing vector fields whose integral curves are geodesics, it is shown that the corresponding manifold is either flat, or otherwise of compact type with positive constant sectional curvature and dimension equal to 1, 3 or 7. Explicit representations of momentum operators and the associated Casimir element will be discussed for the 3-sphere. It will be verified that the structure constants of the underlying Lie algebra are proportional (...) to 2ħ/R, where R is the curvature radius of the sphere. This results in a countable energy and momentum spectrum of freely moving particles. It is shown that the maximum resolution of the possible momenta is given by the de-Broglie wave length λ=πR, which is identical to the diameter of the manifold. The corresponding covariant position operators are defined in terms of geodesic normal coordinates and the associated commutator relations of position and momentum are established. (shrink)