One of the characteristic aspects of Daniel Dennett’s thought is his belief in the explanatory power of science. For Dennett, in order to make progress with certain philosophical problems, e.g. questions about the nature of consciousness, philosophers need to engage with the findings of empirical science. In this paper, I will take up the question of the relation between science and philosophy and I will start by giving a general overview of Dennett’s view of this relation while also addressing the (...) question of whether he can properly be said to embrace scientism. In the second part of this paper, I will argue that philosophical thinking is continuous with science and that, though at the level of theoretical frameworks the intension of the words “philosophy” and “science” are the same, there is a distinction that can be made in practice if we look at the extensions of the terms. -/- . (shrink)

Plasticity is a central concept in the philosophy of Catherine Malabou and the theory of animation. And yet, the temporal dimension of transformation and mutability that Malabou foregrounds in her philosophy is missing from recent theoretical accounts of plasticity in animation studies​. ​In these accounts, plasticity appears as a mode of spatial extension, conveying the elasticity of form across a Cartesian timeline, whereas Malabou aims to understand time’s own metamorphosis and self-differentiation. This article invokes Malabou’s theorization of plasticity as the (...) becoming of time itself rather than the becoming of things in time to rethink the perception of life-like movement in animation. Reviewing the techniques of animation that Frank Thomas and Ollie Johnston describes in The Illusion of Life as “drawing in the fourth dimension”, I argue that Malabou’s characterization of plasticity as the capacity “to see (what is) coming” (voir venir) gets to the heart of animation as an art of subjective anticipation. Utilizing the human perceptual system’s tendency to invent new structures and relationships in response to changing inputs from the environment, animation prepares us to anticipate the unforeseeable and to perceive an order of movement typically concealed by the movement of objects in space. (shrink)

There is a steadily growing literature on the role of the immune system in psychiatric disorders. So far, these advances have largely taken the form of correlations between specific aspects of inflammation (e.g. blood plasma levels of inflammatory markers, genetic mutations in immune pathways, viral or bacterial infection) with the development of neuropsychiatric conditions such as autism, bipolar disorder, schizophrenia and depression. A fundamental question remains open: why are psychiatric disorders and immune responses intertwined? To address this would require a (...) step back from a historical mind–body dualism that has created such a dichotomy. We propose three contributions of active inference when addressing this question: translation, unification, and simulation. To illustrate these contributions, we consider the following questions. Is there an immunological analogue of sensory attenuation? Is there a common generative model that the brain and immune system jointly optimise? Can the immune response and psychiatric illness both be explained in terms of self-organising systems responding to threatening stimuli in their external environment, whether those stimuli happen to be pathogens, predators, or people? Does false inference at an immunological level alter the message passing at a psychological level (or vice versa) through a principled exchange between the two systems? (shrink)

I will contrast the two main approaches to the foundations of statistical mechanics: the individualist approach and the ensemblist approach. I will indicate the virtues of each, and argue that the conflict between them is perhaps not as great as often imagined.

By utilizing the concept of quantum decoherence, augmented by the novel theory of quantum Darwinism, to understand the transition from the quantum to the classical worlds, the scaling up of the concept of quantum entanglement2018 to the biological level offers a fascinating metaphor for the presence of the creative spirit in nature and the “flesh” of Incarnation. This in turn provides helpful theological metaphors for articulating divine presence at the level of life in theistic evolution, partially addressing the issue of (...) evolutionary theodicy by supporting the concept of deep Incarnation. The point of understanding the Incarnation as deeply entangled enfleshment is that it brings the suffering of creation into the life of the Redeemer as well as the Creator, facilitating redemption and hope through the divine life. (shrink)

In this paper I aim to demonstrate that Rudolf Carnap's analysis of the application of information theory within physics, an intellectual-historical precedent of current philosophical criticisms toward this tendency, is justified. First, Carnap and Bar-Hillel (1952) underlined the unjustified ‘semantification’ of Shannon entropy Furthermore, Carnap criticized the ‘physicalization’ of Shannon entropy, but that criticism was not accepted by the physics community of the 1950s (Köhler 2001). Finally, in the posthumously published "Two Essays on Entropy" Carnap (1977) developed a critical assessment (...) of entropy concepts that showed some deep conceptual and interpretative deficiencies in Jaynes (1957a) and Brillouin’s (1956) informational approaches to thermophysics. (shrink)

Niche construction theory concerns how organisms can change selection pressures by altering the feature–factor relationship between themselves and their environment. These alterations are standardly understood to be brought about through two kinds of organism–environment interaction: perturbative and relocational niche construction. We argue that a reconceptualization is needed on the grounds that if a niche is understood as the feature–factor relationship, then there are three fundamental ways in which organisms can engage in niche construction: constitutive, relational, and external niche construction. We (...) further motivate our reconceptualization by showing some examples of organismic activities that fall outside of the current categorization of niche construction, but nonetheless should be included. We end by discussing two objections to niche construction and show how our reconceptualization helps to undercut these objections. 1Introduction2Niche Construction Theory 2.1The standard account of niche construction2.2Two problems with the standard account of niche construction3Three Kinds of Niche Construction 3.1Constitutive niche construction3.2Relational niche construction3.3External niche construction4Conceptual Improvement on Niche Construction Theory 4.1Constitutive niche construction4.2Relational niche construction4.3External niche construction5The Status of Niche Construction Theory within Evolutionary Theory 5.1Is niche construction a helpful addition to evolutionary theory?5.2Is niche construction an evolutionary process?6Conclusion. (shrink)

The living forms represented in this paper are sets of parts that spontaneously increase in organization. Their organizations are measured by an information-theoretic function derived from the work of Boltzmann and Shannon. We briefly review its derivation in the context of the troubled role of mathematics in biology, and then define the function. We illustrate its nature by measuring the 22 different organizations of a set of eight things; and we facilitate its use by defining the parameters that determine an (...) amount of organization. The measure is then applied to show that the organization of limb pairs on free-living arthropods, based on data given by Cisne, confirms a pattern of increasing organization in their evolution from the Cambrian era to the present. Further applications measure the changes in organizations of ideal (theoretical) life forms, and contrasting changes in inanimate systems. Our main results represent the reproduction of unicellular organisms, and the formation of hierarchies, as processes of increasing organization. (shrink)

In The Logic of Life, François Jacob reconstructed the history of heredity from the seventeenth century to the present, emphasizing the role of physics in the development of biology. Quantum mechanics provided questions, methods, and techniques to molecular biologists. In the 1960s, physics also provided the organizational model. Jacob worked on the creation of the European Molecular Biology Laboratory, on the model of CERN (European Organization for Nuclear Research). I argue that reflection on the relation between molecular biology and physics (...) played a part in the making of The Logic of Life. Between the mid-1960s and the early 1970s, Jacob focused on relations between the “genealogy” of his molecular biology work and the development of physics at scientific, institutional, and historical levels. He thus brought molecular biology to the attention of a larger public, following the history of the Institut Pasteur, whose public mission had to be reaffirmed to grant its survival. With The Logic of Life, Jacob became an influential intellectual who engaged with scholars in human sciences. He promoted his view of the development of molecular biology as a model for a possible new discipline: bioanthropology. (shrink)

The theory of quantum mechanics has often been thought to show an affinity with logical empiricism: in both, observation plays a central role, and questions about what is unobservable are dismissed. However, there were also strong tensions between the logical empiricism of the Vienna Circle and implications drawn from quantum physics. In the 1920s and 1930s, many physicists thought that quantum mechanics revealed a limit to what could be known scientifically, and this opened the door to a wide range of (...) speculations, in which quantum mechanics was connected with free will, organic life, psychology, and religion—speculations in which many leading quantum physicists were engaged. Members of the Vienna Circle, such as Frank and Schlick, looked at quantum mechanics for a confirmation of their empiricist views, but they were at the same time critical about these wider implications drawn from quantum mechanics, which in their eyes were connected with broader mystical and irrational trends in society. They engaged in particular with the views of Bohr and Jordan, both of whom expressed a sympathy for logical empiricism while at the same time arguing for claims that proved hard to reconcile with the scientific world conception of the Vienna Circle. (shrink)

People who habituate to stress show a repetition-induced response attenuation—neuroendocrine, cardiovascular, neuroenergetic, and emotional—when exposed to a threatening environment. But the exact dynamics underlying stress habituation remain obscure. The free energy principle offers a unifying account of self-organising systems such as the human brain. In this paper, we elaborate on how stress habituation can be explained and modelled using the free energy principle. We introduce habituation priors that encode the agent’s tendency for stress habituation and incorporate them in the agent’s (...) decision-making process. Using differently shaped goal priors—that encode the agent’s goal preferences—we illustrate, in two examples, the optimising behaviour of agents. We show that habituation minimises free energy by reducing the precision of goal preferences. Reducing the precision of goal priors means that the agent accepts adverse states. Acceptance or tolerance of adverse outcomes may explain why habituation causes people to exhibit an attenuation of the stress response. Given that stress habituation occurs in brain regions where goal priors are encoded, i.e., in the ventromedial prefrontal cortex and that these priors are encoded as sufficient statistics of probability distributions, our approach seems plausible from an anatomical-functional and neuro-statistical point of view. The ensuing formal and generalisable account—based on the free energy principle—further motivate our novel treatment of stress habituation. Our analysis suggests that stress habituation has far-reaching consequences, protecting against the harmful effects of toxic stress, but on the other hand making the acceptability of precarious living conditions and the development of the obese type 2 diabetes mellitus phenotype more likely. (shrink)

Complex systems are to be seen as typically having multiple levels of organization. For instance, in the behavioural and cognitive sciences, there has been a long lasting trend, promoted by the seminal work of David Marr, putting focus on three distinct levels of analysis: the computational level, accounting for the What and Why issues, the algorithmic and the implementational levels specifying the How problem. However, the tremendous developments in neuroscience knowledge about processes at different scales of organization together with the (...) complexity of today cognitive theories suggest that there will hardly be only three levels of explanation. Instead, there will be many different degrees of commitments corresponding to the different granularities—from high-level (behavioural) models to low-level (neural and molecular) models of the cognitive research program. For instance, Bayesian approaches, that are usually advocated for formalizing Marr’s computational level and rational behaviour, have even been adopted to model synaptic plasticity and axon guidance by molecular gradients. As a result, we can consider the behavioural scientist as dealing with models at a multiplicity of levels. The purpose of this Research Topic in Frontiers in Theoretical and Philosophical Psychology is to promote an approach to the role of the levels and explanation and models which is of interest for cognitive scientists, neuroscientists, psychologists, behavioural scientists, and philosophers of science. (shrink)

This article reconsiders the theoretical role of the genetic code. By drawing on published and unpublished sources from the 1950s, I analyse how the code metaphor was actually employed by the scientists who first promoted its use. The analysis shows that the term ‘code’ picked out mechanism sketches, consisting of more or less detailed descriptions of ordinary molecular components, processes, and structural properties of the mechanism of protein synthesis. The sketches provided how-possibly explanations for the ordering of amino acids by (...) nucleic acids. I argue that employing the code metaphor was justified in virtue of its descriptive-denotational and explanatory roles, and because it highlighted a similarity with conventional codes that was particularly salient at the time. 1 Introduction2 Coding Schemes in the 1950s2.1 The research problem: Determining amino acid sequences2.2 The solution: Mapping schemes or ‘codes’3 The Code Metaphor Played Descriptive and Explanatory Roles4 Theness of Codes and the Expendability of the Code Metaphor5 The Role of Arbitrariness6 Conclusions. (shrink)

Early 20th century philosopher Henri Bergson posited an initial push that propelled the diversity of life forward into a varied, novel future: The élan vital, a necessary force or impulse that animated life’s progress and development. His idea had largely been abandoned by mid-century. Even so, much of the conceptual and explanatory work this impulse targeted is yet in want of an explanation. In particular, Bergson’s derelict ideas on evolution addressed three areas that have once again become relevant in the (...) effort to unite evolutionary genetics, biological development, and ecological context : the purposeful nature of individual organisms and their parts; the integrative, holistic, non-linear emergent dynamics seen in evolutionary processes; and how genuine novelty emerges into the universe :422, 2016; Simondon et al. in On the mode of existence of technical objects. Univocal series, Univocal Publishing LLC, Minneapolis, 2017; Bang, in: Winther-Lindqvist, Bang, Valsiner Nothingness: philosophical insights into psychology, Transaction Publishers, Somerset, 2016; Moreno and Mossio in Biological autonomy: a philosophical and theoretical enquiry. History, philosophy and theory of the life sciences, Springer, Dordrecht, 2015). In this paper I argue that Bergson’s ideas may yet be relevant to these questions, and his work warrants a reexamination in light of current problems in evolutionary biology. This is not a call to ‘return’ to Bergson, nevertheless his notions about complexity suggest ways of looking at current biological problems in ways that offer a heuristic insight worth entertaining. Bergson’s Nobel Prize-winning book, Creative Evolution, provided a strikingly prescient early 20th century framework for understanding how Darwinian evolution acts as an engine for generating new forms, University Press of America, Lanham, Bergson 1911). (shrink)