Philosophical naturalism is ambiguous between conjoining philosophy with science or with nature understood scientifically. Reconciliation of this ambiguity is necessary but rarely attempted. Feminist science studies often endorse the former naturalism but criticize the second. Karen Barad's agential realism, however, constructively reconciles both senses. Barad then challenges traditional metaphysical naturalisms as not adequately accountable to science. She also contributes distinctively to feminist reinterpretations of objectivity as agential responsibility, and of agency as embodied, worldly, and intra-active.