The ArgumentThis essay addresses the historiographical question of how to study scientific instruments and the connections between them without rigidly determining the boundaries of the object under historical scrutiny beforehand. To do this, I will explore an episode in the early history of the tachistoscope — defined, among other things, as an instrument for the brief exposure of visual stimuli in experimental psychology. After looking at the tachistoscope described by physiologist Volkmann in 1859, I will turn to the gravity chronometer, (...) constructed by Cattell at Wundt's Leipzig institute of psychology in the 1880s. Taking Wittgenstein's notion of family resemblances as a methodological suggestion to travel from one member to another to find out just how members relate to one another, I will investigate part of the family to which both the tachistoscope and the gravity chronometer turn out to belong. A detailed analysis of these instruments, using both historical sources and historical accounts of psychological instruments, may demonstrate that the instrument is not a standard package that, if well applied, will simply secure good results. Each package needs to be assembled again and again; the particular package that is assembled may differ on different occasions. Thus an alternative is developed to an understanding of instruments as univocally functioning material means. (shrink)

Academia’s mathematical metaphysics are briefly explored en route to an elaboration of the qualitatively rigorous requirements underpinning the calibration and unambiguous interpretation of quantitative instrumentation in any science. Of particular interest are Gadamer’s emphases on number as the paradigm of the noetic, on the role of play in interpretation, and on Hegel’s sense of method as the activity of the thing itself that thought experiences. These point toward and overlap with (1) Latour’s study of the metrological social networks through which (...) technological phenomena are brought into language as modes of being that can be understood, and (2) the way that Rasch’s models for measurement comprise a potential beginning for metaphysically astute, qualitatively and quantitatively integrated, mathematical methods in the social sciences. The paper closes with observations on the general problem that is philosophy, the need to remain open to multiplicities of meaning even as clear understandings are sought and obtained. (shrink)

Recently, oysters have been identified by the US Food and Drug Administration (USFDA) as a risky food to eat because they may or may not contain the pathogenic bacteria Vibrio parahaemolyticus. The USFDA's attempts to manage the risk manifest themselves in a “Quantitative Risk Assessment”, a report that attempts to quantify and predict the number of oyster eaters that will fall ill from Vibrio. In seeking to produce knowledge and eliminate uncertainty, the USFDA, through the use of a discourse of (...) quantification, does the opposite. Instead, we argue, documents such as risk assessments are best understood as kinds of rhetorical practice. According to this perspective, these documents are epistemologically and ontologically reductive, produce uncertainty, politicize the act of eating, and serve an ironic function. (shrink)

ArgumentUsing the notion of styles of knowledge we refer to the ways diverse scientific communities claim to produce true knowledge, their understandings regarding the attitudes and values that scientists should have in order to grasp natural and social reality, and the practices and technologies developed within such styles. This paper analyzes scientific and medical enterprises that explored the relationship between environment, population, and society in Colombia between 1850 and 1920. We argue that similar styles of knowledge production were shared in (...) human geography, medical geography, and climatic physiology at the mid-nineteenth century; and that some physicians working in bacteriology and physiology since the 1880s established epistemic boundaries between their work and earlier scientific activities, while others found these distinctions irrelevant. However, the historical actors committed to any of the styles of knowledge production explored in this article agreed on the local specificity of their objects of inquiry, therefore questioning European science. These styles of knowledge production also shaped different ways of perceiving and addressing national problems. Hence, this article is a contribution to the recent literature on both historical epistemology and social and cultural history of science and medicine. (shrink)

ArgumentGlass vessels such as flasks and test tubes play an ambiguous role in the historiography of modern laboratory research. In spite of the strong focus on the role of materiality in the last decades, the scientific glass vessel – while being symbolically omnipresent – has remained curiously neglected in regard to its materiality. The popular image ortoposof the transparent, neutral, and quasi-immaterial glass container obstructs the view of the physico-chemical functionality of this constitutive inner boundary in modern laboratory environments and (...) its material historicity. In order to understand how glass vessels were able to provide a stable epistemic containment of spatially enclosed experimental phenomena in the new laboratory ecologies emerging in the nineteenth and early twentieth century, I will focus on the history of thematerialstandardization of laboratory glassware. I will follow the rise of a new awareness for measurement errors due to the chemical agency of experimental glass vessels, then I will sketch the emergence of a whole techno-scientific infrastructure for the improvement of glass container quality in late nineteenth-century Germany. In the last part of my argument, I will return to the laboratory by looking at the implementation of this glass reform that created a newoikosfor the inner experimental milieus of modern laboratory research. (shrink)

Historical epistemology is a form of intellectual history focused on “the history of categories that structure our thought, pattern our arguments and proofs, and certify our standards for explanation”. Under this umbrella, historians have been studying the changing meanings of “objectivity,” “impartiality,” “curiosity,” and other virtues believed to be conducive to good scholarship. While endorsing this historicization of virtues and their corresponding vices, the present article argues that the meaning and relative importance of these virtues and vices can only be (...) determined if their mutual dependencies are taken into account. Drawing on a detailed case study—a controversy that erupted among nineteenth-century orientalists over the publication of R. P. A. Dozy'sDe Israëlieten te Mekka —the paper shows that nineteenth-century orientalists were careful to examine the degree to which Dozy practiced the virtues they considered most important, the extent to which these virtues were kept in balance by other ones, the extent to which these virtues were balanced by other scholars’ virtues, and the extent to which they were expected to be balanced by future scholars’ work. Consequently, this article argues that historical epistemology might want to abandon its single-virtue focus in order to allow balances, hierarchies, and other dependency relations between virtues and vices to move to the center of attention. (shrink)

ArgumentThis essay places some therapeutic vaccines, including particularly the diphtheria antitoxin, into their larger historical context of the late nineteenth century. As industrially produced drugs, these vaccines ought to be seen in connection with the structural changes in medicine and pharmacology at the time. Given the spread of industrial culture and technology into the field of medicine and pharmacology, therapeutic vaccines can be understood as boundary objects that required and facilitated communication between industrialists, medical researchers, public health officials, and clinicians. (...) It was in particular in relation to evaluation and testing for efficacy in animal models that these medicines became a model for twentieth-century medicine. In addition, these medicines came into being as a parallel invention in two very distinct local cultures of research: the Institut Pasteur in Paris and the Institut für Infektionskrankheiten in Berlin. While their local cultural origins were plainly visible, the medicines played an important role in the alignment of the methods and objects that took place in bacteriology research in France and Germany in the 1890s. This article assesses the two locally specific regimes for control in France and in Imperial Germany. In France the Institut Pasteur, building on earlier successful vaccines, enjoyed freedom from scrutinizing control. The tight and elaborate system of control that evolved in Imperial Germany is portrayed as being reliant on experiences that were drawn from the dramatic events that surrounded the launching of a first example of so-called “bacteriological medicine,” tuberculin, in 1890. (shrink)

ArgumentThe procedure ofWertbestimmungplayed a vital role in the implementation of serum therapy and the standardization of mass-produced pharmaceuticals. In fin-de-siècle Germany, a legal framework was put in place to guarantee serum quality and safety and to minimize any associated public health risks. Because the sera were biological remedies, it was difficult to produce them in uniform quality and the procedure ofWertbestimmung, i.e. determining the potency of the serum based on an objective and comparable value, was extremely complex. Various agents such (...) as bacteria cultures, serum hosts, or test animals had to be regulated. In the years after 1895, numerous efforts to stabilize the procedures ofWertbestimmungwere undertaken by serum producers and members of the state-run survey institute responsible for overseeing serum production. Despite efforts to stabilize the framework and to generate a reliable reference system, the framework's environment and agents were in constant flux: new producers entered the market and procedures were expanded to include other biologicals as well. The article describes the dynamics involved in the sustained efforts to maintain a stable framework in the face of constant alterations between 1895 and the 1920s. (shrink)

The essays in this special issue shed new light on the transnational movement and exchange of researchers, data, theories, and scientific objects in the anthropological and genetic study of human populations in the twentieth century. Historians have long stressed how the study of race and human populations in this period served to create a national identity for emerging nation states. More recently, historical narratives of anthropology and human genetics have emphasized the global scale of research networks in these sciences. This (...) issue explores the specific routes, crossings, and interactions between national and international contexts prompted by the study of races and populations. The essays reveal not only how... (shrink)