The paper introduces a special issue of the journal Philosophical Problems in Science (ZFN) on the topic of the nature and norms of scientific explanation.

The ontic conception of explanation is predicated on the proposition that “explanation is a relation between real objects in the world” and hence, according to this approach, scientific explanation cannot take place absent such a premise. Despite the fact that critics have emphasized several drawbacks of the ontic conception, as for example its inability to address the so-called “abstract explanations”, the debate is not settled and the ontic view can claim to capture cases of explanation that are non-abstract, such as (...) causal relations between events. However, by eliminating the distinction between abstract and non-abstract explanations, it follows that ontic and epistemic proposals can no longer contend to capture different cases of explanation and either all are captured by the ontic view or all are captured by the epistemic view. On closer inspection, it turns out that the ontic view deals with events that fall outside the scientists’ scope of observation and that it does not accommodate common instances of explanation such as explanations from false propositions and hence it cannot establish itself as the dominant philosophical stance with respect to explanation. On the contrary, the epistemic conception does account for almost all episodes of explanation and can be described as a relation between representations, whereby the explanans transmit information to the explanandum and that this information can come, dependent on context, in the form of any of the available theories of explanation (law-like, unificatory, causal and non-causal). The range of application of the ontic view thus is severely restricted to trivial cases of explanation that come through direct observation of the events involved in an explanation and explanation is to be mostly conceived epistemically. (shrink)

After Wesley Salmon’s causal-mechanical stance on explanation in the 1980s, the ontic-epistemic debate of scientific explanations appeared to be resolved in the philosophy of science. However, since the twenty-first century, this debate has been rekindled among philosophers who focus on mechanistic explanations. Nevertheless, its issues have evolved, necessitating scrutiny of the new trends in this debate and a comparison with the original controversy between Carl Hempel and Salmon. The primary objective of this paper is to elucidate three categorical dimensions in (...) the ontic-epistemic debates, spanning from the original to the recent controversies. Subsequently, it will explore why the conception of explanation is linked to representations, what conditions are necessary for linguistic expressions to be explanatory, and what roles norms play in explanation. Consequently, contrary to the common stereotype, it will be argued that mechanistic explanations are more likely to be epistemic rather than ontic. (shrink)

This paper adds to the philosophical literature on mechanistic explanation by elaborating two related explanatory functions of idealisation in mechanistic models. The first function involves explaining the presence of structural/organizational features of mechanisms by reference to their role as difference-makers for performance requirements. The second involves tracking counterfactual dependency relations between features of mechanisms and features of mechanistic explanandum phenomena. To make these functions salient, we relate our discussion to an exemplar from systems biological research on the mechanism for countering (...) heat shock—the heat shock response system—in Escherichia coli bacteria. This research also reinforces a more general lesson: ontic constraint accounts in the literature on mechanistic explanation provide insufficiently informative normative appraisals of mechanistic models. We close by outlining an alternative view on the explanatory norms governing mechanistic representation. (shrink)

In a recent article published in Ergo and entitled "Ontic explanation is either ontic or explanatory, but not both," Cory Wright and Dingmar van Eck have sought to undermine any ontic approach to explanation, providing three arguments to show that an epistemic approach is "the only game in town." I show that each of their arguments is straightforwardly question-begging. For brevity, I make my counter-arguments by showing how the claims of Sheredos (2016)-whom Wright & van Eck cite as an ally-undermine (...) each of their own arguments. The consumer update is: there is no new decisive argument against an ontic view, the epistemic view is not the only game in town, and reconciliation between the ontic and epistemic views remains possible. -/- . (shrink)

What features will something have if it counts as an explanation? And will something count as an explanation if it has those features? In the second half of the 20th century, philosophers of science set for themselves the task of answering such questions, just as a priori conceptual analysis was generally falling out of favor. And as it did, most philosophers of science just moved on to more manageable questions about the varieties of explanation and discipline-specific scientific explanation. Often, such (...) shifts are sound strategies for problem-solving. But leaving fallow certain basic conceptual issues can also result in foundational debates. (shrink)

Recent attempts to reconcile the ontic and epistemic approaches to explanation propose that our best explanations simply fulfill epistemic and ontic norms simultaneously. I aim to upset this armistice. Epistemic norms of attaining general and systematic explanations are, I argue, autonomous of ontic norms: they cannot be fulfilled simultaneously or in simple conjunction with ontic norms, and plausibly have priority over them. One result is that central arguments put forth by ontic theorists against epistemic theorists are revealed as not only (...) question-begging, but ultimately self-defeating. Another result is that a more nuanced reconciliation of the epistemic and ontic views is required: we should regard good explanatory practice as a dynamic process with distinct phases of epistemic and ontic success. (shrink)

In this paper we consider mechanistic explanations for biologic malfunctions. Drawing on Lipton’s work on difference making, we offer three reasons why one should distinguish i) mechanistic features that only make a difference to the malfunction one aims to explain, from ii) features that make a difference to both the malfunction and normal functioning. Recognition of the distinction is important for a) repair purposes, b) mechanism discovery, and c) understanding. This analysis extends current mechanistic thinking, which fails to appreciate the (...) distinction. We illustrate our contribution with a case on sleeping disorders as arising from disruptions of circadian rhythms. (shrink)

Philosophical accounts of scientific explanation are broadly divided into ontic and epistemic views. This paper explores the idea that the lexical ambiguity of the verb to explain and its nominalisation supports an ontic conception of explanation (Salmon 1989; Craver 2007). I analyse one argument which challenges this strategy by criticising the claim that explanatory talk is lexically ambiguous (Wright, European Journal of Philosophy of Science 2(3), 375–394, 2012). I propose that the linguistic mechanism of transfer of meaning (Nunberg, Journal of (...) Semantics 12(2), 109–132, 1995) provides a better account of the lexical alternations that figure in the systematic polysemy of explanatory talk, and evaluate the implications of this proposal for the debate between ontic and epistemic conceptions of scientific explanation. (shrink)

This work addresses biological explanations and aims to provide a philosophical account which brings together logical-procedural and historical-processual aspects when considering molecular pathways. It is argued that, having molecular features as explananda, a particular non-classical logical language – Zsyntax – can be used to formally represent, in terms of logical theorems, types of molecular processes, and to grasp how we get from one molecular interaction to another, hence explaining why a given outcome occurs. Expressing types of molecular biology processes in (...) terms of the Zsyntax language allows us to represent causal interactions by taking into account their context-sensitivity, and amounts to partly reviving the spirit of the so-called received view of explanation – which aimed to capture scientific explanatory accounts in terms of their logical structure and their appealing to nomological relations. Such a partial revival is pursued by invoking here non-classical deductions and empirical generalisations, which are called to provide the epistemic norms to explain the behavior of molecular pathways. (shrink)