During the second half of the last century, the importance of serendipitous events in scientific frameworks has been progressively recognized, fueling hard debates about their role, nature, and structure in philosophy and sociology of science. Alas, while discussing the relevance of the topic for the comprehension of the nature of scientific discovery, the philosophical literature has hardly paid attention to the cognitive significance of serendipity, accepting rather than examining some of its most specific features, such as its game-changing effect, the (...) unexpectedness of its occurrence, and its affinity with the concept of “luck”. Thus, in this paper we aim at analyzing these characteristics in the light of their cognitive implications in the recognition, performance, and possible stimulation of serendipitous events in relation to scientific discoveries. (shrink)