Clonal complexes in biomedical ontologies

In Barry Smith (ed.), ICBO 2009: Proceedings of the First International Conference on Biomedical Ontology. Buffalo: NCOR. pp. 168 (2009)
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An accurate classification of bacteria is essential for the proper identification of patient infections and subsequent treatment decisions. Multi-Locus Sequence Typing (MLST) is a genetic technique for bacterial classification. MLST classifications are used to cluster bacteria into clonal complexes. Importantly, clonal complexes can serve as a biological species concept for bacteria, facilitating an otherwise difficult taxonomic classification. In this paper, we argue for the inclusion of terms relating to clonal complexes in biomedical ontologies.

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Barry Smith
University at Buffalo


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