# Diagrams as locality aids for explanation and model construction in cell biology

*Biology and Philosophy*27 (5):705-721 (2012)

**Abstract**

Using as case studies two early diagrams that represent mechanisms of the cell division cycle, we aim to extend prior philosophical analyses of the roles of diagrams in scientific reasoning, and specifically their role in biological reasoning. The diagrams we discuss are, in practice, integral and indispensible elements of reasoning from experimental data about the cell division cycle to mathematical models of the cycle’s molecular mechanisms. In accordance with prior analyses, the diagrams provide functional explanations of the cell cycle and facilitate the construction of mathematical models of the cell cycle. But, extending beyond those analyses, we show how diagrams facilitate the construction of mathematical models, and we argue that the diagrams permit nomological explanations of the cell cycle. We further argue that what makes diagrams integral and indispensible for explanation and model construction is their nature as locality aids: they group together information that is to be used together in a way that sentential representations do not.

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Archival date: 2015-08-26

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References found in this work BETA

Discovering Complexity Decomposition and Localization as Strategies in Scientific Research.Bechtel, William & Richardson, Robert C.

Explanation: A Mechanist Alternative.Bechtel, William

Integrating Psychology and Neuroscience: Functional Analyses as Mechanism Sketches.Piccinini, Gualtiero & Craver, Carl

Functional Analysis.Cummins, Robert

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Citations of this work BETA

Why Do Biologists Use so Many Diagrams?Sheredos, Benjamin; Burnston, Daniel; Abrahamsen, Adele & Bechtel, William

Constraint‐Based Reasoning for Search and Explanation: Strategies for Understanding Variation and Patterns in Biology.Green, Sara & Jones, Nicholaos

Modeling complexity: cognitive constraints and computational model-building in integrative systems biology.MacLeod, Miles & Nersessian, Nancy J.

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