Scientific Method, Miscellaneous

This paper integrates symbolic thought and experimental research. We hypothesized that symbolic narratives provide homeostasis for the complex adaptive system that is personality. Our interpretation of a dream was based, in part, on this hypothesis. We found that the dream retold the myth of Saturn. When, by direct experiment, we tried to falsify our interpretation, our results supported our interpretation and thereby supported our hypothesis. Previously, evidence for this hypothesis had been only anecdotal. __________________________________________ For an audio-record of entire class: (...) link is given on 1st page of the text you download from this page. (shrink)

In this essay, I will explain why Methodological Naturalism (MN) fails as a demarcating criteria for science. I will argue that MN is not precise enough to be useful for demarcation, unable to follow the evidence where it leads, not theologically neutral (despite its stated goals as such), and difficult to justify (and currently unjustified) as an ontological or epistemic principle.

It is sometimes said that simulation can serve as epistemic substitute for experimentation. Such a claim might be suggested by the fast-spreading use of computer simulation to investigate phenomena not accessible to experimentation (in astrophysics, ecology, economics, climatology, etc.). But what does that mean? The paper starts with a clarification of the terms of the issue and then focuses on two powerful arguments for the view that simulation and experimentation are ‘epistemically on a par’. One is based on the claim (...) that, in experimentation, no less than in simulation, it is not the system under study that is manipulated but a system that ‘stands-in’ for it. The other one highlights the pervasive use of models in experimentation. It will be argued that these arguments, as compelling as they might seem, are each based on a mistaken interpretation of experimentation and that, far from simulation and experimentation being epistemically on a par, they do not have the same epistemic function, do not produce the same kind of epistemic results. (shrink)

Progress in the last few decades in what is widely known as “Chaos Theory” has plainly advanced understanding in the several sciences it has been applied to. But the manner in which such progress has been achieved raises important questions about scientific method and, indeed, about the very objectives and character of science. In this presentation, I hope to engage my audience in a discussion of several of these important new topics.

Analiza de informații are multe asemănări epistemologice importante cu știința (rezolvarea problemelor, descoperirea, utilizarea cu abilitate a instrumentelor, verificarea cererilor de cunoștințe). Metafora puzzle este folosită atât în activitatea de informații cât și în arheologie. Ambele discipline implică colectarea de dovezi pentru a construi o imagine cât mai completă posibil. Firmele private inovatoare adaptează din ce în ce mai mult modelul serviciilor de informații la lumea afacerilor pentru a ajuta la planificarea propriilor strategii. Practica medicală de diagnosticare a identificării, colectării, (...) analizării și diseminării este similară cu cea a activității de informații. DOI: 10.13140/RG.2.2.35820.72324. (shrink)

David Singer afirmă că, în prezent, amenințarea constituie principalul obiectiv al agențiilor de informații. Activitatea de informații poate fi considerată ca fiind procesul prin care anumite tipuri de informații sunt solicitate, colectate, analizate și diseminate, și modul în care sunt concepute și desfășurate anumite tipuri de acțiuni secrete. Ciclul informațional reprezintă un set de procese utilizate pentru a furniza informații utile în luarea deciziilor. Ciclul constă din mai multe procese. Domeniul conex al contrainformațiilor este însărcinat cu împiedicarea eforturilor informative ale (...) altora. DOI: 10.13140/RG.2.2.10807.06563. (shrink)

Les analystes sont dans le domaine des « connaissances ». L'activité de renseignement fait référence à la connaissance et les types de problèmes abordés sont des problèmes de connaissance. Nous avons donc besoin d'un concept de travail basé sur la connaissance. Nous avons besoin d'une compréhension de base de ce que nous savons et de la manière dont nous le savons, de ce que nous ne savons pas et même de ce qui peut être connu et de ce qui ne (...) peut pas être connu. L'analyse du renseignement implique de « transformer des faits disparates en conclusions concentrées. » DOI: 10.13140/RG.2.2.11223.91043. (shrink)

Programele de cercetare permit dezvoltarea unor teorii mai complexe. Termenii pot fi aplicați atât la teorii individuale cât și la programe. În cazul în care se aplică teoriilor din cadrul unui program de cercetare, consider că acestea devin la rândul lor programe de cercetare, pe care le putem numi subprograme de cercetare. Spre deosebire de revoluțiile științifice ale lui Kuhn, Lakatos a presupus că existența simultană a mai multor programe de cercetare este norma. Știința se confruntă în prezent cu o (...) astfel de situație inedită: două teorii incompatibile, dar ambele acceptate de comunitatea științifică descriu aceeași realitate în două moduri diferite. DOI: 10.13140/RG.2.2.11153.28005. (shrink)

The general theory of relativity was developed using as a nucleus a principle of symmetry: the principle of general covariance. Initially, Einstein saw the principle of general covariance as an extension of the principle of relativity in classical mechanics, and in SR. For Einstein, the principle of general covariance was a crucial postulate in the development of GR. The freedom of the GR diffeomorphism (the invariance of the form of the laws under transformations of the coordinates depending on the arbitrary (...) functions of space and time) is a "local" spacetime symmetry, as opposed to the "global" spacetime symmetries of the SR (which depend instead on the constant parameters ). DOI: 10.13140/RG.2.2.30854.32326. (shrink)

Metodologia, în activitatea de informații, constă din metodele folosite pentru a lua decizii despre amenințări, în special în cadrul disciplinei de analiză a informațiilor. Teoria prismatică a lui Robert Flood, denumită de alții drept pluralism metodologic, folosește metafora pentru a descrie gândirea creativă și de transformare, respectiv o prismă care descompune lumina în culorile sale componente prin dubla refracție. Tehnicile analitice structurale sunt folosite pentru a provoca judecata, la identificarea mentalităților, depășirea prejudecăților, stimularea creativității și gestionarea incertitudinii. DOI: 10.13140/RG.2.2.10589.36329.

This article is devoted to define and characterize ‘Science’ as a discipline by the fundamental principles of scientific investigation. In particular, we propose and argue that ‘Science’ be defined by a set of principles / criteria which underlies scientific- investigation. We argue that this set must include the following principles: (1) Rationality, (2) Objectivity (3) Universality, (4) Internal Consistency, (5) Uniqueness, (6) Reproducibility, (7) The Principle of Falsification, (8) Simplicity and Elegance and (9) Experimental Observation and Verification. We elaborate, through (...) illustrative examples, the justification of the above set of criteria. `Scientific temper’ essentially means the cultivation of these principles, as attitudes / value-system adopted as “ways of life”. We discuss the relevance of the inculcation of scientific temper in the modern context. Finally, the scope and limitations of the scientific method are highlighted and an attempt is made to dispel several misconceptions and myths associated with Science and scientists. (shrink)

Many prominent critiques of philosophical methods proceed by suggesting that some method is unreliable, especially in comparison to some alternative method. In light of this, it may seem natural to conclude that these (comparatively) unreliable methods should be abandoned. Drawing upon work on the division of cognitive labour in science, we argue things are not so straightforward. Rather, whether an unreliable method should be abandoned depends heavily on the crucial question of how we should divide philosophers’ time and effort between (...) different methods, in order to maximise our prospects of achieving epistemic success. We show that, in a range of cases, even a (comparatively) unreliable method deserves to be allocated some of these resources. (shrink)

One of the most controversial interpretations in quantum mechanics is the Wigner-Neumann interpretation, according to which the superstitions collapse only when a conscious observer observes the quantum system. In general, there is much opposition against this specific interpretation and the reasons are more philosophical than purely scientific. By refuting a specific refutation of the Wigner-Neumann interpretation postulated by Anderson and Carpenter, this paper shows how cancelling the Wigner interpretation is simply not possible at least with our current understanding of the (...) cosmos. What is more, a brief overview of the philosophical dogmas underlying the opposition against this specific interpretation are discussed. The debate is more philosophical than scientific and if science wants to progress it should reunite with philosophy and start asking the simple questions once again and with a clear mind. (shrink)

Drawing on empirical findings, a number of philosophers have recently argued that people who use English as a foreign language may face a linguistic bias in academia in that they or their contributions may be perceived more negatively than warranted because of their English. I take a critical look at this argument. I first distinguish different phenomena that may be conceptualized as linguistic bias but that should be kept separate to avoid overgeneralizations. I then examine a range of empirical studies (...) that philosophers have cited to argue that people who use English as a foreign language are subject to linguistic bias in academia. I contend that many of these studies do not sufficiently support key claims that philosophers have made about linguistic bias, are challenged by counterevidence, and lack generalizability. I end by introducing methodological recommendations that may help philosophers develop more convincing empirically informed arguments regarding linguistic bias. (shrink)

After two centuries, the Diltheyan idea of the incommensurability of the natural and social sciences remains hegemonic. Alternative visions have since been overlooked; in this regard, the Baden neo-Kantian school showed that any divergence concerns implied method and not the phenomenal object of studies. W. Windelband coined the terms “nomological” and “idiographic” to underline how each discipline can be explained as a science of both law and events. To begin, I will show how complex thinking can expand and institute a (...) general integrative frame that overcomes the assumed incommensurability. By “complex,” I mean an anti-reductionist approach to understanding and a consequent ability to reveal the phenomenal world in terms of nested self-organized systems. Social and natural systems are persistent coalescences of individual entities showing series of interduality such as unicity and multiplicity, top-down conservation and bottom-up inno- vation, constraint of law and freedom of agencies. The two instances are maintained together by the rejection of abstracted and isolated concepts and the embrace of a general principle of indeterminacy resolving the apparent contradiction within the parallelization of the extremes as two different moments of analyses rooted in the social and natural classical methods. This paper considers both a) the Positivist attempt in the XIX century to approach the study of social phenomena in terms of law and b) the emergence of a general social science embracing the principle of acasuality, adapted from the study of the subatomic phenomenal world in quantum theory. Finally, this paper sketches how complex methodology can address historical and social studies with system theory in order to overcome classical dualities such as determinism vs. freedom, social vs. individual, and top down conservation vs. bottom up innovation in the form of an integrative parallelization. (shrink)

Universities are knowledge institutions. Compared to several other knowledge institutions (e.g. schools, government research organisations, think tanks), research universities have unusual, anarchic organisational features. We argue that such anarchic features are not a weakness. Rather, they reflect the special standing of research universities among knowledge institutions. We contend that the distributed, self-organising mode of knowledge production maintains a diversity of approaches, topics and solutions needed in frontier research, which involves generating relevant knowledge under uncertainty. Organisational disunity and inconsistencies should sometimes (...) be protected by institutional structures and procedures in order for research universities to best serve their purpose as knowledge institutions. The quality control for the knowledge produced stems from knowledge fields, clusters of knowledge and research that exist beyond the confines of individual organisations. The diversity of epistemic contributions is therefore kept in check by the order imposed by the internal logic of science as a social practice. Our argument provides a new defence for the autonomy of research conducted at universities. (shrink)

In this paper I discuss Mark Steiner’s view of the contribution of mathematics to physics and take up some of the questions it raises. In particular, I take up the question of discovery and explore two aspects of this question – a metaphysical aspect and a related epistemic aspect. The metaphysical aspect concerns the formal structure of the physical world. Does the physical world have mathematical or formal features or constituents, and what is the nature of these constituents? The related (...) epistemic question concerns humans’ cognitive ability to reach the formal structure of the physical world. Among other things, I explore the interaction of mathematical and non-mathematical cognition in physical discovery. (shrink)

Replicability is widely regarded as one of the defining features of science and its pursuit is one of the main postulates of meta-research, a discipline emerging in response to the replicability crisis. At the same time, replicability is typically treated with caution by philosophers of science. In this paper, we reassess the value of replicability from an epistemic perspective. We defend the orthodox view, according to which replications are always epistemically useful, against the more prudent view that claims that it (...) is useful in very limited circumstances. Additionally, we argue that we can learn more about the original experiment and the limits of the discovered effect from replications at different levels. We hold that replicability is a crucial feature of experimental results and scientists should continue to strive to secure it. (shrink)

En este artículo se sostiene la siguiente hipótesis: si una hipótesis tiene valor epistémico para Hume, este valor tiene que provenir de la intuición. Para ello se consideran las tres posibles fuentes de conocimiento en su pensamiento: la demostración, la experiencia y la intuición. Considerando que Hume presenta su doctrina de la creencia como una hipótesis, se argumenta que el valor epistémico de las hipótesis no puede provenir de la demostración ni de la experiencia y, por tanto, o las hipótesis (...) carecen de valor epistémico o su valor epistémico proviene de la intuición. Para sostener la hipótesis propuesta se ofrece un análisis de la evidencia textual sobre la hipótesis y la intuición a la luz de la literatura disponible sobre el tema. (shrink)

[This book replaces the - discontinued - first edition of 'Introduction to Interdisciplinary Research' (2016, by Menken & Keestra)] We are increasingly realizing that, as a result of technological developments and globalization, problems are becoming so complex that they can only be solved through cooperation between scientists from different disciplines. Healthcare, climate change, food security, globalization, and quality of life are just a few examples of issues that require scientists to work across disciplines. In many cases, extra-academic stakeholders must be (...) involved in order to arrive at robust solutions. Young academics are being called on to step beyond the boundaries of traditional disciplines to contribute to addressing fundamental, often societal problems. As a result of these developments, an interdisciplinary approach is becoming increasingly necessary and popular in higher education. Students need to learn more about how to integrate and apply knowledge, methods, and skills from different fields. The crucial step of integration within interdisciplinary research is treated extensively in this textbook, which contains a comprehensive ‘interdisciplinary integration toolbox’. In addition, students must learn to collaborate in teams. An Introduction to Interdisciplinary Research serves as a systematic manual to guide students through this interdisciplinary research process. (shrink)

Good physical experiments conform to the basic methodological standards of experimental design: they are objective, reliable, and valid. But is this also true of thought experiments? Especially problems of personal identity have engendered hypothetical scenarios that are very distant from the actual world. These imagined situations have been conspicuously ineffective at resolving conflicting intuitions and deciding between the different accounts of personal identity. Using prominent examples from the literature, I argue that this is due to many of these thought experiments (...) not adhering to the methodological standards that guide experimental design in nearly all other disciplines. I also show how empirically unwarranted background assumptions about human physiology render some of the hypothetical scenarios that are employed in the debate about personal identity highly misleading. (shrink)

Usual narratives among prehistoric archaeologists consider typological approaches as part of a past and outdated episode in the history of research, subsequently replaced by technological, functional, chemical, and cognitive approaches. From a historical and conceptual perspective, this paper addresses several limits of these narratives, which (1) assume a linear, exclusive, and additive conception of scientific change, neglecting the persistence of typological problems; (2) reduce collective developments to personal work (e.g. the “Bordes’” and “Laplace’s” methods in France); and (3) presuppose the (...) coherence and identity of these “methods” over time. It explores the case of the “Structural and analytical typology” method, developed in France, Spain, and Italy from the 1950s to the 2000s by Georges Laplace and his collaborators for lithic implements. This paper (1) provides a detailed historical account of the evolving content of this collective endeavour over five decades; (2) it addresses the epistemological question of what makes the identity and unity of a scientific method, demonstrating that the core component of the “analytical typology” lies in its particular way to represent real-world phenomena through its notation system; and (3) it reveals how this little known but significant episode of advances in the methods and theory of archaeology, contemporary but independent of the “New Archaeology” trend in English-speaking archaeology, was instrumental in the continuation of evolutionary perspectives in France and in the development of quantitative and formal methods in archaeology in southwestern Europe, foreseeing crucial knowledge representation issues raised today by digital methods in archaeology and data curation. (shrink)

"Correlation is not causation" is one of the mantras of the sciences—a cautionary warning especially to fields like epidemiology and pharmacology where the seduction of compelling correlations naturally leads to causal hypotheses. The standard view from the epistemology of causation is that to tell whether one correlated variable is causing the other, one needs to intervene on the system—the best sort of intervention being a trial that is both randomized and controlled. In this paper, we argue that some purely correlational (...) data contains information that allows us to draw causal inferences: statistical noise. Methods for extracting causal knowledge from noise provide us with an alternative to randomized controlled trials that allows us to reach causal conclusions from purely correlational data. (shrink)

"David Ricardo has been acclaimed - or vilified - for merits he would never have dreamt of, or sins for which he was entirely innocent. Entrenched mythology labels him as a utilitarian economist, an enemy of the working class, an impractical theorist, a scientist with 'no philosophy at all' and the author of a formalist methodological revolution. Exploring a middle ground between theory and biography, this book explores the formative intellectual encounters of a man who came to economic studies via (...) other experiences, thus bridging the gap between the historical Ricardo and the economist's Ricardo. The chapters undertake a thorough analysis of Ricardo's writings in their context, asking who was speaking, what audience was being addressed, with what communicative intentions, using what kind of lexicon and communicative conventions, and starting with what shared knowledge. The work opens in presenting the different religious communities with which Ricardo was in touch. It goes on to describe his education in the leading science of the time - geology - before he turned to the study of political economy. Another chapter discusses five 'philosophers' - students of logic, ethics and politics - with whom he was in touch. From correspondence, manuscripts and publications, the closing chapters reconstruct, firstly, Ricardo's ideas on scientific method, the limits of the 'abstract science' and its application, secondly, his ideas on ethics and politics and their impact on strategies for improving the condition of the working class. This book sheds new light on Ricardian economics, providing an invaluable service to readers of economic methodology, philosophy of economics, the history of economic thought, political thought and philosophy. (shrink)

Recent epistemology of modality has seen a growing trend towards metaphysics-first approaches. Contrastingly, this paper offers a more philosophically modest account of justifying modal claims, focusing on the practices of scientific modal inferences. Two ways of making such inferences are identified and analyzed: actualist-manipulationist modality and relative modality. In AM, what is observed to be or not to be the case in actuality or under manipulations, allows us to make modal inferences. AM-based inferences are fallible, but the same holds for (...) practically all empirical inquiry. In RM, modal inferences are evaluated relative to what is kept fixed in a system, like a theory or a model. RM-based inferences are more certain but framework-dependent. While elements from both AM and RM can be found in some existing accounts of modality, it is worth highlighting them in their own right and isolating their features for closer scrutiny. This helps to establish their relevant epistemologies that are free from some strong philosophical assumptions often attached to them in the literature. We close by showing how combining these two routes amounts to a view that accounts for a rich variety of modal inferences in science. (shrink)

Sözde-bilim ile ilgili bu tartışmalar uluslararası literatürde yapılıyor olsa da Türkiye’de henüz bu konuların eleştirel olarak ele alındığı söylenemez. Dolayısıyla sözde-bilimlerin eleştirel olarak ele alındığı öğrenme ortamlarının öğrencilerin bilime ve sözde-bilime ilişkin algılarına etkisi üzerine yapılacak araştırmalar konunun daha iyi anlaşılmasını sağlayabilir ve belki de ilerideki program değişiklerinde öğretim programlarında sözde-bilimin yer bulmasının yolunu açabilir.

ArgumentIn the United States, scientific knowledge is brought before the courts by way of testimony – the testimony of scientific experts. We argue that this expertise is best understoodfirstas related to the quality of the underlying scienceand thenin terms of who delivers it. Bloodstain pattern analysis (BPA), a contemporary forensic science, serves as the vaulting point for our exploration of objectivity as a metric for the quality of a science in judicial contexts. We argue that BPA fails to meet the (...) minimal standard set by Helen Longino’s social-procedural account of objectivity (1990, 2002). In light of some pressing issues for social-procedural accounts, we offer an infrastructural account of objectivity. This account offers what amounts to a friendly amendment to Longino’s account and adds to the ways in which we might analyze social-procedural objectivity. Finally, we address an issue that is pressing in the legal context: given that scientific knowledge is delivered by individuals, not communities, at least in U.S. courts, we (may) need a way to evaluate individual scientific and epistemic agents. We suggest a means for making this evaluation that is derived from our infrastructural account of objectivity. (shrink)

Transcendental philosophy was not born like Athena out of Zeus’s head, mature and in full armour from the very beginning. That is why in both prefaces to the Critique of Pure Reason (1781 and 1787) Kant introduces the concept of transcendental philosophy as an “idea.” The idea understood architectonically develops slowly and only gradually acquires a definite form. As witnessed by the works of Kant himself and of his predecessors and followers, the idea of transcendental philosophy has undergone a series (...) of changes and adjustments compared to the initial plan. In this context, my goal is not simply exegesis and historical investigation of transcendental philosophy, but also to look at it from a systematic and methodological perspective. I examine the concept of transcendental philosophy from the viewpoint of programmatic metaphilosophy. The first part discusses programmatics as a distinct subsection of metaphilosophy. I argue that Kant’s architectonic methodology and the methodology of Lakatos can be used to understand the inception, development and degradation of philosophical systems. In the second part I look at the project of transcendental philosophy and the stages of its development from the standpoint of architectonics. The third part shows that Lakatos’s methodology can provide a detailed insight into the elements of transcendental philosophy, a clear idea of its logic and identify the component parts that can be improved and developed. In spite of the different levels of detailing and epistemological prerequisites, the methodologies of Kant and Lakatos can be combined to achieve a metaphilosophically informed and progressive understanding of philosophical projects. (shrink)

William S. Lewis examines the contribution to philosophy of science made by Lefebvre, in the context of his membership of the French Communist Party.

The world is in a state of crisis. Global problems that threaten our future include: the climate crisis; the destruction of natural habitats, catastrophic loss of wild life, and mass extinction of species; lethal modern war; the spread of modern armaments; the menace of nuclear weapons; pollution of earth, sea and air; rapid rise in the human population; increasing antibiotic resistance; the degradation of democratic politics, brought about in part by the internet. It is not just that universities around the (...) world have failed to help humanity solve these global problems; even worse, they have made the genesis of these problems possible. Modern science and technology, developed in universities, have made possible modern industry and agriculture, modern hygiene and medicine, modern power production and travel, modern armaments, which in turn make possible much that is good, all the great benefits of the modern world, but also all the global crises that now threaten our future. What has gone wrong? The fault lies with the whole conception of inquiry built into universities around the world. The basic idea is to help promote human welfare by, in the first instance, acquiring scientific knowledge and technological know-how. First, knowledge is to be acquired; once acquired, it can be applied to help solve social problems, and promote human welfare. But this basic idea is an intellectual disaster. Judged from the standpoint of promoting human welfare, it is profoundly and damagingly irrational, in a structural way. As a result of being restricted to the tasks of acquiring and applying knowledge, universities are prevented from doing what they most need to do to help humanity solve global problems, namely, engage actively with the public to promote action designed to solve global problems. We need urgently to bring about a revolution in universities around the world, wherever possible, so that their central task becomes to help humanity learn how to solve the climate crisis and other problems of living, local and global, so that we may make progress towards a good, civilized world. Almost every branch and aspect of the university needs to change. (shrink)

A Série Investigação Filosófica, uma iniciativa do Núcleo de Ensino e Pesquisa em Filosofia do Departamento de Filosofia da UFPel e do Grupo de Pesquisa Investigação Filosófica do Departamento de Filosofia da UNIFAP, sob o selo editorial do NEPFil online e da Editora da Universidade Federal de Pelotas, com auxílio financeiro da John Templeton Foundation, tem por objetivo precípuo a publicação da tradução para a língua portuguesa de textos selecionados a partir de diversas plataformas internacionalmente reconhecidas, tal como a Stanford (...) Encyclopedia of Philosophy, por exemplo. O objetivo geral da série é disponibilizar materiais bibliográficos relevantes tanto para a utilização enquanto material didático quanto para a própria investigação filosófica. (shrink)

This paper provides a critical review of the debate over the philosophical foundations of mixed methods research and examines the notion of philosophical foundations. It distinguishes axiology-oriented from ontology-oriented philosophical foundations. It also identifies three different senses of philosophical foundations of mixed methods research. The weak sense of philosophical foundations (e.g., pragmatism) merely allows the possibility of the integration of both quantitative and qualitative methods/data/designs. The moderate sense of philosophical foundations (e.g., transformativism) provide a good reason to use mixed methods (...) in (at least some) social scientific research. The strong sense of philosophical foundations (e.g., dialectical pluralism) justifies a normative thesis that mixed methods research should be encouraged in (at least some) social scientific research. (shrink)

Pragmatism is typically understood as a philosophy embedded in scientific inquiry. Thinkers, like Charles Peirce (1877), C.I. Lewis (1923) and Susan Haack (1998) envisioned pragmatism and its scientific inquiry as a method of systematizing our beliefs and acquiring knowledge. They thought that scientific practice and its implied standards, techniques, and values is the only source of hope for scientific and philosophical progress. In this dissertation, I construct a pragmatic approach to the meta-ethical questions of our moral truths, beliefs and principles (...) that proposes a normative systematization of ethics grounded in moral practice, development and experimentation. I argue that maintaining a pragmatic faith in the origination and formation of our moral constitutions will provide us with a realist, cognitivist and objective view of reality subject to the capacities of our human cognition and empirical evidence and not subject to metaphysical and universal methods of reasoning. (shrink)

Precision medicine and molecular systems medicine (MSM) are highly utilized and successful approaches to improve understanding, diagnosis, and treatment of many diseases from bench-to-bedside. Especially in the COVID-19 pandemic, molecular techniques and biotechnological innovation have proven to be of utmost importance for rapid developments in disease diagnostics and treatment, including DNA and RNA sequencing technology, treatment with drugs and natural products and vaccine development. The COVID-19 crisis, however, has also demonstrated the need for systemic thinking and transdisciplinarity and the limits (...) of MSM: the neglect of the bio-psycho-social systemic nature of humans and their context as the object of individual therapeutic and population-oriented interventions. COVID-19 illustrates how a medical problem requires a transdisciplinary approach in epidemiology, pathology, internal medicine, public health, environmental medicine, and socio-economic modeling. Regarding the need for conceptual integration of these different kinds of knowledge we suggest the application of general system theory (GST). This approach endorses an organism-centered view on health and disease, which according to Ludwig von Bertalanffy who was the founder of GST, we call Organismal Systems Medicine (OSM). We argue that systems science offers wider applications in the field of pathology and can contribute to an integrative systems medicine by (i) integration of evidence across functional and structural differentially scaled subsystems, (ii) conceptualization of complex multilevel systems, and (iii) suggesting mechanisms and non-linear relationships underlying the observed phenomena. We underline these points with a proposal on multi-level systems pathology including neurophysiology, endocrinology, immune system, genetics, and general metabolism. An integration of these areas is necessary to understand excess mortality rates and polypharmacological treatments. In the pandemic era this multi-level systems pathology is most important to assess potential vaccines, their effectiveness, short-, and long-time adverse effects. We further argue that these conceptual frameworks are not only valid in the COVID-19 era but also important to be integrated in a medicinal curriculum. (shrink)

This article explains Kant’s claim that sciences must take, at least as their ideal, the form of a ‘system’. I argue that Kant’s notion of systematicity can be understood against the background of de Jong & Betti’s Classical Model of Science (2010) and the writings of Georg Friedrich Meier and Johann Heinrich Lambert. According to my interpretation, Meier, Lambert, and Kant accepted an axiomatic idea of science, articulated by the Classical Model, which elucidates their conceptions of systematicity. I show that (...) Kant’s critique of the mathematical method is compatible with his adherence to this axiomatic conception of science. I further show that systematicity furthers traditionally accepted logical ideals of scientific knowledge, which explains why Meier and Kant think that sciences must be ‘systematic’. (shrink)

This paper argues that the main global critiques of scientism lose their punch because they rely on an uncharitable definition of their target. It focuses on epistemological scientism and divides it into four categories in terms of how strong (science is the only source of knowledge) or weak (science is the best source of knowledge) and how narrow (only natural sciences) or broad (all sciences or at least not only the natural sciences) they are. Two central arguments against scientism, the (...) (false) dilemma and self‐referential incoherence, are analysed. Of the four types of epistemological scientism, three can deal with these counterarguments by utilizing two methodological principles: epistemic evaluability of reliability and epistemic opportunism. One hopes that these considerations will steer the discussion on scientism to more fruitful pastures in the future. For example, there are interesting methodological considerations concerning what evaluability or reliability and epistemic opportunism entail. (shrink)

We provide a novel articulation of the epistemic peril of p-hacking using three resources from philosophy: predictivism, Bayesian confirmation theory, and model selection theory. We defend a nuanced position on p-hacking: p-hacking is sometimes, but not always, epistemically pernicious. Our argument requires a novel understanding of Bayesianism, since a standard criticism of Bayesian confirmation theory is that it cannot represent the influence of biased methods. We then turn to pre-analysis plans, a methodological device used to mitigate p-hacking. Some say that (...) pre-analysis plans are epistemically meritorious while others deny this, and in practice pre-analysis plans are often violated. We resolve this debate with a modest defence of pre-analysis plans. Further, we argue that pre-analysis plans can be epistemically relevant even if the plan is not strictly followed—and suggest that allowing for flexible pre-analysis plans may be the best available policy option. (shrink)

Our understanding of folk and scientific psychology often informs the law’s conclusions regarding questions about the voluntariness of a defendant’s action. The field of psychology plays a direct role in the law’s conclusions about a defendant’s guilt, innocence, and term of incarceration. However, physical sciences such as neuroscience increasingly deny the intuitions behind psychology. This paper examines contemporary biases against the autonomy of psychology and responds with considerations that cast doubt upon the legitimacy of those biases. The upshot is that (...) if reasonable doubt is established regarding whether psychology’s role in the law should be displaced, then there is room for future work to be done with respect to the truth of psychology’s conclusions about criminal responsibility. (shrink)

For centuries, science was considered as something radically different from religion. Yet, the foundations of true science are deeply religious in nature. This paper seeks to show how religion is the only foundation needed for the formulation of scientific theories, since it provides the core principles on which the building of exact sciences is based upon. Our need to understand the cosmos and our faith in us being able to do so, are the main prerequisites for conducting science; prerequisites that (...) are derived from our belief in us being the sons of God and, thus, being able to read His mind. From its birth on 7 March 1277 up to today, science seems to be the only logical attitude of religious people towards the unknown cosmos. (shrink)

The idea of science being the best – or the only – way to reach the truth about our cosmos has been a major belief of modern civilization. Yet, science has grown tall on fragile legs of clay. Every scientific theory uses axioms and assumptions that by definition cannot be proved. This poses a serious limitation to the use of science as a tool to find the truth. The only way to search for the latter is to redefine the former (...) to its original glory. In the days well before Galileo and Newton, science and religion were not separated. They worked together to discover the truth and while the latter had God as its final destination, the former had God as its starting point. Science is based on the irrational (unproven) belief that the world is intelligible along many other assumptions. This poses a serious limitation to science that can only be overcome if we accept the irrationality of the cosmos. The motto “Credo quia absurdum” holds more truth than one can ever realize at first glance. There is nothing logical in logic, whereas there is deep wisdom in the irrational. For while the former tries to build castles on moving sand, the latter digs deep inside the depths of existence itself in order to build on the most concrete foundations that there can be: the cosmos itself. The only way forward is backwards. Backwards to a time when religion led the quest for knowledge by accepting what we cannot know, rather than trying to comprehend what we do not. Science was anyway based on that in the first place. (shrink)

Fukuyama's 'The End of History' has referred to Kojeve's 'homogenous state' as some sort of conceptual container for the evolving idea of liberal democracy. This paper critically re-assess the homogeneity of state as final stage of liberal idea and defends civil society in terms of democratic governance. It also invites to discuss the role of scholars as public intellectuals and repels the ideological abuse of the scientific method.

Experimental design is one aspect of a scientific method. A well-designed, properly conducted experiment aims to control variables in order to isolate and manipulate causal effects and thereby maximize internal validity, support causal inferences, and guarantee reliable results. Traditionally employed in the natural sciences, experimental design has become an important part of research in the social and behavioral sciences. Experimental methods are also endorsed as the most reliable guides to policy effectiveness. Through a discussion of some of the central concepts (...) associated with experimental design, including controlled variation and randomization, this chapter will provide a summary of key ethical issues that tend to arise in experimental contexts. In addition, by exploring assumptions about the nature of causation and by analyzing features of causal relationships, systems, and inferences in social contexts, this chapter will summarize the ways in which experimental design can undermine the integrity of not only social and behavioral research but policies implemented on the basis of such research. (shrink)

It is generally accepted among philosophers of science that hypothesis testing is a key methodological feature of science. As far as philosophical theories of confirmation are con...

This book on Philosophy of Science includes a comprehensive discussion of ontology, epistemology, and axiology of science in the constellation of various other knowledge, as well as the development of scientific knowledge holistically contained in each module in this course. These three things are branches of philosophy which are very useful for students of Teacher Training and Education in mediating the learning and learning process so that the essence of Philosophy of Science can then be implemented within the scope of (...) professionalism in particular and society in general and the challenges of the industrial era 4.0 in the 20th century 21 The discussion on ontology is focused on elements of empirical reality (empericism) such as facts, data, and information without releasing it from rational reality (rationalism), and its position in scientific activities. The epistemology of science is focused on the scientific method and its operationalization in research methodology. The axiology of science discusses the values ​​associated with scientific activities and their uses, both internally, externally, and socially. (shrink)

In response to Anderson and Arzyutov’s paper, I argue that ambiguities in the Russian social-scientific concept of “etnos” reveal its place in what I call a “field style” for thinking and doing science. Tolerance for ambiguity is, I suggest, a methodological strength of the field sciences. I support these reflections by also addressing the etnos concept’s origins in the complex history of Ukrainian nationalism.

We philosophers of science have before us an important new task that we need urgently to take up. It is to convince the scientific community to adopt and implement a new philosophy of science that does better justice to the deeply problematic basic intellectual aims of science than that which we have at present. Problematic aims evolve with evolving knowledge, that part of philosophy of science concerned with aims and methods thus becoming an integral part of science itself. The outcome (...) of putting this new philosophy into scientific practice would be a new kind of science, both more intellectually rigorous, and one that does better justice to the best interests of humanity. (shrink)

I present a recent historical case from cosmology—the story of inflationary cosmology—and on its basis argue that solving explanatory problems is a reliable method for making progress in science. In particular, I claim that the success of inflationary theory at solving its predecessor’s explanatory problems justified the theory epistemically, even in advance of the development of novel predictions from the theory and the later confirmation of those predictions.

For many old and new mechanists, Mechanism is both a metaphysical position and a thesis about scientific methodology. In this paper we discuss the relation between the metaphysics of mechanisms and the role of mechanical explanation in the practice of science, by presenting and comparing the key tenets of Old and New Mechanism. First, by focusing on the case of gravity, we show how the metaphysics of Old Mechanism constrained scientific explanation, and discuss Newton’s critique of Old Mechanism. Second, we (...) examine the current mechanistic metaphysics, arguing that it is not warranted by the use of the concept of mechanism in scientific practice, and motivate a thin conception of mechanism (the truly minimal view), according to which mechanisms are causal pathways for a certain effect or phenomenon. Finally, we draw analogies between Newton’s critique of Old Mechanism and our thesis that the metaphysical commitments of New Mechanism are not necessary in order to illuminate scientific practice. (shrink)