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  1. Human Germline Genome Editing: On the Nature of Our Reasons to Genome Edit.Robert Sparrow - 2021 - American Journal of Bioethics 22 (9):4-15.
    Ever since the publication of Derek Parfit’s Reasons and Persons, bioethicists have tended to distinguish between two different ways in which reproductive technologies may have implications for the...
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  • Practical Ethics.Peter Singer - 1979 - New York: Cambridge University Press. Edited by Susan J. Armstrong & Richard George Botzler.
    For thirty years, Peter Singer's Practical Ethics has been the classic introduction to applied ethics. For this third edition, the author has revised and updated all the chapters and added a new chapter addressing climate change, one of the most important ethical challenges of our generation. Some of the questions discussed in this book concern our daily lives. Is it ethical to buy luxuries when others do not have enough to eat? Should we buy meat from intensively reared animals? Am (...)
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  • The Moral Obligation to Create Children with the Best Chance of the Best Life.Julian Savulescu & Guy Kahane - 2008 - Bioethics 23 (5):274-290.
    According to what we call the Principle of Procreative Beneficence, couples who decide to have a child have a significant moral reason to select the child who, given his or her genetic endowment, can be expected to enjoy the most well-being. In the first part of this paper, we introduce PB, explain its content, grounds, and implications, and defend it against various objections. In the second part, we argue that PB is superior to competing principles of procreative selection such as (...)
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  • Disability: a welfarist approach.Julian Savulescu & Guy Kahane - 2011 - Clinical Ethics 6 (1):45-51.
    In this paper, we offer a new account of disability. According to our account, some state of a person's biology or psychology is a disability if that state makes it more likely that a person's life will get worse, in terms of his or her own wellbeing, in a given set of social and environmental circumstances. Unlike the medical model of disability, our welfarist approach does not tie disability to deviation from normal species’ functioning, nor does it understand disability in (...)
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  • Virtue ethics and the selection of children with impairments: A reply to Rosalind McDougall.Carla Saenz - 2009 - Bioethics 24 (9):499-506.
    In ‘Parental Virtues: A New Way of Thinking about the Morality of Reproductive Actions’ Rosalind McDougall proposes a virtue-based framework to assess the morality of child selection. Applying the virtue-based account to the selection of children with impairments does not lead, according to McDougall, to an unequivocal answer to the morality of selecting impaired children. In ‘Impairment, Flourishing, and the Moral Nature of Parenthood,’ she also applies the virtue-based account to the discussion of child selection, and claims that couples with (...)
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  • Reproductive CRISPR does not cure disease.Tina Rulli - 2019 - Bioethics 33 (9):1072-1082.
    Given recent advancements in CRISPR‐Cas9 powered genetic modification of gametes and embryos, both popular media and scientific articles are hailing CRISPR’s life‐saving, curative potential for people with serious monogenic diseases. But claims that CRISPR modification of gametes or embryos, a form of germline engineering, has therapeutic value are deeply mistaken. This article explains why reproductive uses of CRISPR, and germline engineering more generally, do not treat or save lives that would otherwise have a genetic disease. Reproductive uses of CRISPR create (...)
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  • Why Human Germline Editing is More Problematic than Selecting Between Embryos: Ethically Considering Intergenerational Relationships.Christoph Rehmann-Sutter - 2018 - The New Bioethics 24 (1):9-25.
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  • Reasons and Persons.Derek Parfit - 1984 - Oxford, GB: Oxford University Press.
    Challenging, with several powerful arguments, some of our deepest beliefs about rationality, morality, and personal identity, Parfit claims that we have a false view about our own nature. It is often rational to act against our own best interersts, he argues, and most of us have moral views that are self-defeating. We often act wrongly, although we know there will be no one with serious grounds for complaint, and when we consider future generations it is very hard to avoid conclusions (...)
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  • Historical Injustice and the Right of Return.Lukas H. Meyer - 2004 - Theoretical Inquiries in Law 5 (2):305-316.
    There are two main sources of theoretical doubt regarding the validity of claims for reparation: the questions arising from the non-identity problem and those arising from the supersession thesis. Neither of them significantly undermines the Palestinian refugees’ claims to reparations and a right of return.
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  • Rethinking Procreation: Why it Matters Why We Have Children.Mianna Lotz - 2011 - Journal of Applied Philosophy 28 (2):105-121.
    Attempts to explain the intuitive wrongfulness in alleged ‘wrongful life’ cases commonly do so by attributing harmful wrongdoing to the procreators in question. Such an approach identifies the resulting child as having been, in some sense, culpably harmed by their coming into existence. By contrast, and enlarging on work elsewhere, this paper explores the relevance of procreative motivation, rather than harm, for determining the morality of procreative conduct. I begin by reviewing the main objection to the harm-based approach, which arises (...)
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  • Non-identity, self-defeat, and attitudes to future children.Guy Kahane - 2009 - Philosophical Studies 145 (2):193-214.
    Although most people believe that it is morally wrong to intentionally create children who have an impairment, it is widely held that we cannot criticize such procreative choices unless we find a solution to Parfit’s non-identity problem. I argue that we can. Jonathan Glover has recently argued that, in certain circumstances, such choices would be self-defeating even if morally permissible. I argue that although the scope of Glover’s argument is too limited, it nevertheless directs attention to a moral defect in (...)
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  • Genethics: Moral Issues in the Creation of People.David Heyd - 1992 - University of California Press.
    Unprecedented advances in medicine, genetic engineering, and demographic forecasting raise new questions that strain the categories and assumptions of traditional ethical theories. Heyd's approach resolves many paradoxes in intergenerational justice, while offering a major test case for the profound problems of the limits of ethics and the nature of value. This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and (...)
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  • Gene Editing, Identity and Benefit.Thomas Douglas & Katrien Devolder - 2022 - Philosophical Quarterly 72 (2):305-325.
    Some suggest that gene editing human embryos to prevent genetic disorders will be in one respect morally preferable to using genetic selection for the same purpose: gene editing will benefit particular future persons, while genetic selection would merely replace them. We first construct the most plausible defence of this suggestion—the benefit argument—and defend it against a possible objection. We then advance another objection: the benefit argument succeeds only when restricted to cases in which the gene-edited child would have been brought (...)
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  • Balancing Procreative Autonomy and Parental Responsibility.Tom Buller & Stephanie Bauer - 2011 - Cambridge Quarterly of Healthcare Ethics 20 (2):268-276.
    In Rationality and the Genetic Challenge: Making People Better? Matti Häyry provides a clear and informed discussion and analysis of a number of competing answers to the above questions. Häyry describes three main perspectives on the morality of prenatal genetic diagnosis , the “restrictive,” “moderate,” and “permissive” views, and his analysis illuminates that these views can be distinguished in terms of their different “rationalities”—their respective understanding of what counts as a reasonable choice for parents to make in light of PGD.
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  • Choosing Who Will Be Disabled: Genetic Intervention and the Morality of Inclusion.Allen Buchanan - 1996 - Social Philosophy and Policy 13 (2):18.
    The Nobel prize-winning molecular biologist Walter Gilbert described the mapping and sequencing of the human genome as “the grail of molecular biology.” The implication, endorsed by enthusiasts for the new genetics, is that possessing a comprehensive knowledge of human genetics, like possessing the Holy Grail, will give us miraculous powers to heal the sick, and to reduce human suffering and disabilities. Indeed, the rhetoric invoked to garner public support for the Human Genome Project appears to appeal to the best of (...)
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  • The Defective Character Solution to the Non-identity Problem.Ben Bramble - 2021 - Journal of Philosophy 118 (9):504-520.
    The non-identity problem is that some actions seem morally wrong even though, by affecting future people’s identities, they are worse for nobody. In this paper, I further develop and defend a lesser-known solution to the problem, one according to which when such actions are wrong, it is not because of what they do or produce, but rather just because of why they were performed. In particular, I argue that the actions in non-identity cases are wrong just when and because they (...)
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  • Genetic Enhancement and the Child’s Right to an Open Future.Davide Battisti - 2020 - Phenomenology and Mind 19 (19):212.
    In this paper, I analyze the ethical implications of genetic enhancement within the specific framework of the “child’s right to an open future” argument (CROF). Whilst there is a broad ethical consensus that genetic modifications for eradicating diseases or disabilities are in line with – or do not violate – CROF, there is huge disagreement about how to ethically understand genetic enhancement. Here, I analyze this disagreement and I provide a revised formulation of the argument in the specific field of (...)
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  • Affecting future individuals: Why and when germline genome editing entails a greater moral obligation towards progeny.Davide Battisti - 2021 - Bioethics 35 (5):1-9.
    Assisted reproductive technologies have greatly increased our control over reproductive choices, leading some bioethicists to argue that we face unprecedented moral obligations towards progeny. Several models attempting to balance the principle of procreative autonomy with these obligations have been proposed. The least demanding is the minimal threshold model (MTM), according to which every reproductive choice is permissible, except creating children whose lives will not be worth living. Hence, as long as the future child is likely to have a life worth (...)
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  • Choosing Tomorrow's Children: The Ethics of Selective Reproduction.Stephen Wilkinson - 2010 - Oxford, GB: Oxford University Press.
    To what extent should parents be allowed to use reproductive technologies to determine the characteristics of their future children? Is there something morally wrong with choosing what their sex will be, or with trying to 'screen out' as much disease and disability as possible before birth? Stephen Wilkinson offers answers to such questions.
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  • The Non-Identity Problem and the Ethics of Future People.David Boonin - 2014 - New York, NY: Oxford University Press.
    David Boonin presents a new account of the non-identity problem: a puzzle about our obligations to people who do not yet exist. He provides a critical survey of solutions to the problem that have been proposed, and concludes by developing an unorthodox alternative solution, one that differs fundamentally from virtually every other approach.
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  • Ectogenesis: Artificial Womb Technology and the Future of Human Reproduction.Scott Gelfand & John R. Shook - 2006 - Rodopi.
    This book raises many moral, legal, social, and political, questions related to possible development, in the near future, of an artificial womb for human use. Is ectogenesis ever morally permissible? If so, under what circumstances? Will ectogenesis enhance or diminish women's reproductive rights and/or their economic opportunities? These are some of the difficult and crucial questions this anthology addresses and attempts to answer.
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  • Persons, Interests, and Justice.Nils Holtug - 2010 - Oxford, GB: Oxford University Press.
    In our lives, we aim to achieve welfare for ourselves, that is, to live good lives. But we also have another, more impartial perspective, where we aim to balance our concern for our own welfare against a concern for the welfare of others. This is a perspective of justice. Nils Holtug examines these two perspectives and the relations between them.
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  • Choosing Children: Genes, Disability, and Design.Jonathan Glover - 2006 - Oxford, GB: Oxford University Press UK.
    Progress in genetic and reproductive technology now offers us the possibility of choosing what kinds of children we do and don't have. Should we welcome this power, or should we fear its implications? There is no ethical question more urgent than this: we may be at a turning-point in the history of humanity. The renowned moral philosopher and best-selling author Jonathan Glover shows us how we might try to answer this question, and other provoking and disturbing questions to which it (...)
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  • Harming as causing harm.Elizabeth Harman - 2009 - In M. A. Roberts & D. T. Wasserman (eds.), Harming Future Persons. Springer Verlag. pp. 137--154.
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  • Impairment, flourishing and the moral nature of parenthood.Rosalind McDougall - 2009 - In Kimberley Brownlee & Adam Cureton (eds.), Disability and Disadvantage. Oxford University Press.
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