Science’s theory of evolution purports to explain life and its historical dynamics in a physics/material-only fashion. But this entails a broad reliance on DNA (deoxyribonucleic acid) for inheritance (and thus blueprints), which appears to be implausible for a number of unusual innate behaviors. The immediate unfolding challenge, though, is that the inheritance role is conveniently testable via searches for the DNA origins of a number of human behavioral and health tendencies, and despite enormous efforts those searches have thus far largely (...) failed (i.e., the “absolutely beyond belief” missing heritability problem). This existing case for DNA’s inadequacies will be briefly reviewed herein. The subsequent main analysis considers some big challenges facing DNA associated with some evolutionary dynamics—the acquisition of color vision in primates; instinctive behaviors including the egg-laying practices of emerald jewel wasps; kin selection; and our natural religious beliefs. Together these challenges strongly suggest that the acceptance of DNA as the (complete) language of life was premature. The haphazard and ambiguous nature of DNA/genetic specifications is very unlikely to have provided a vehicle for the exacting blueprints required for the many instinctive behaviors or capacities. Life appears to be more complex than biologists believe. Two possible alternative explanations are briefly considered in the wake of these discussions. Finally, does anyone—beginning with academics—care about this unfolding foundational failure? (shrink)