How do we go about weighing evidence, testing hypotheses, and making inferences? According to the model of _Inference to the Best Explanation_, we work out what to infer from the evidence by thinking about what would actually explain that evidence, and we take the ability of a hypothesis to explain the evidence as a sign that the hypothesis is correct. In _Inference to the Best Explanation_, Peter Lipton gives this important and influential idea the development and assessment it deserves. The (...) second edition has been substantially enlarged and reworked, with a new chapter on the relationship between explanation and Bayesianism, and an extension and defence of the account of contrastive explanation. It also includes an expanded defence of the claims that our inferences really are guided by diverse explanatory considerations, and that this pattern of inference can take us towards the truth. This edition of _Inference to the Best Explanation_ has also been updated throughout and includes a new bibliography. (shrink)

Science depends on judgments of the bearing of evidence on theory. Scientists must judge whether an observation or the result of an experiment supports, disconfirms, or is simply irrelevant to a given hypothesis. Similarly, scientists may judge that, given all the available evidence, a hypothesis ought to be accepted as correct or nearly so, rejected as false, or neither. Occasionally, these evidential judgments can be made on deductive grounds. If an experimental result strictly contradicts a hypothesis, then the truth of (...) the data deductively entails the falsity of the hypothesis. In the great majority of cases, however, the connection between evidence and hypothesis is non-demonstrative, or inductive. In particular, this is so whenever a general hypothesis is inferred to be correct on the basis of the available data, since the truth of the data will not deductively entail the truth of the hypothesis. It always remains possible that the hypothesis is false even though the data are correct. (shrink)

How do we go about weighing evidence, testing hypotheses, and making inferences? The model of " inference to the best explanation " -- that we infer the hypothesis that would, if correct, provide the best explanation of the available evidence--offers a compelling account of inferences both in science and in ordinary life. Widely cited by epistemologists and philosophers of science, IBE has nonetheless remained little more than a slogan. Now this influential work has been thoroughly revised and updated, and features (...) a new introduction and two new chapters. Inference to the Best Explanation is an unrivaled exposition of a theory of particular interest in the fields both of epistemology and the philosophy of science. (shrink)

It is well known that the process of scientific inquiry, according to Peirce, is drivenby three types of inference, namely abduction, deduction, and induction. What isbehind these labels is, however, not so clear. In particular, the common identificationof abduction with Inference to the Best Explanation (IBE) begs the question,since IBE appears to be covered by Peirce's concept of induction, not that of abduction.Consequently, abduction ought to be distinguished from IBE, at least on Peirce's account. The main aim of the paper, (...) however, is to show that this distinction is most relevant with respect to current problems in philosophy of science and epistemology (like attempts to supply suitable notions of realism and truth as well as related concepts like coherence and unification). In particular, I also try to show that (and in what way) Peirce's inferential triad can function as a method that ensures both coherence and correspondence. It is in this respect that his careful distinction between abduction and induction (or IBE) ought to be heeded. (shrink)

"How do we go about weighing evidence, testing hypotheses and making inferences? According to the model of 'inference to the Best explanation', we work out what to inter from the evidence by thinking about what would actually explain that evidence, and we take the ability of a hypothesis to explain the evidence as a sign that the hypothesis is correct. In inference to the Best Explanation, Peter Lipton gives this important and influential idea the development and assessment it deserves." "The (...) second edition has been substantially enlarged and reworked, with a new chapter on the relationship between explanation and Bayesianism, and an extension and defence of the account of contractive explanation. It also includes an expanded defence of the claims that our inferences really are guided by diverse explanatory considerations, and that this pattern of inference can take us towards the truth. This edition of Inference to the Best Explanation has also been updated throughout and incudes a new bibliography."--BOOK JACKET. (shrink)

I argue against the tendency in the philosophy of science literature to link abduction to the inference to the best explanation (IBE), and in particular, to claim that Peireean abduction is a conceptual predecessor to IBE. This is not to discount either abduction or IBE. Rather the purpose of this paper is to clarify the relation between Peireean abduction and IBE in accounting for ampliative inference in science. This paper aims at a proper classification—not justification—of types of scientific reasoning. In (...) particular, I claim that Peireean abduction is an in-depth account of the process of generating explanatory hypotheses, while IBE, at least in Peter Lipton's thorough treatment, is a more encompassing account of the processes both of generating and of evaluating scientific hypotheses. There is then a two-fold problem with the claim that abduction is IBE. On the one hand, it conflates abduction and induction, which are two distinct forms of logical inference, with two distinct aims, as shown by Charles S. Peirce; on the other hand it lacks a clear sense of the full scope of IBE as an account of scientific inference. (shrink)

In this article, I compare two varieties of abduction as reconstructive models for analysing discovery. The first is 'Hansonian abduction', which is based on N. R. Hanson's formulations of abduction. The other is 'Harmanian abduction', the Inference to the Best Explanation (IBE) model, formulated especially by Gilbert Harman. Peter Lipton has analysed processes of discovery on the basis of his developed form of Harmanian abduction. I argue that Hansonian abduction would, however, be a more apt model for this purpose. As (...) an example, I reconstruct, in a Hansonian manner, Ignaz Semmelweis's research on childbed fever and compare it to the IBE reconstruction of Lipton. I argue that Hansonian abduction is in accordance with Lipton's aim of taking into account the distinction between actual and potential explanations on the one hand, and between likely and lovely explanations on the other. I maintain that a developed version of Hansonian abduction combined with loveliness gives an important, new conceptual means for analysing processes of discovery. (shrink)

Now in its fourth edition, Rational Diagnosis and Treatment: Evidence-Based Clinical Decision - Making is a unique book to look at evidence-based medicine and the difficulty of applying evidence from group studies to individual patients._ The book analyses the successive stages of the decision process and deals with topics such as the examination of the patient,_the reliability of clinical data, the logic of diagnosis, the fallacies of uncontrolled therapeutic experience and the need for randomised clinical trials and meta-analyses. It is (...) the main theme of the book that, whenever possible, clinical decisions must be based on the evidence from clinical research, but the authors also explain the pitfalls of such research and the problems involved in applying evidence from groups of patients to the individual patient._ For this new edition, the sections on placebo and meta-analysis and on alternative medicine have been thoroughly updated, and there is more focus on insufficient reporting of harms of interventions. The sections on different research designs describe advantages and limitations, and the increased medicalisation and the effects of cancer screening on health people are noted. A section on academic freedom when clinicians collaborate with industry and ghost authors is added._ This essential reference work integrates the science and statistical approach of evidence-based medicine with the art and humanism of medical practice; distinguishing between data, sets of data, knowledge and wisdom, and their application. Such an intellectually challenging book is ideal for both medical students and doctors who require theoretical and practical clinical skills to help ensure that they apply theory in practice. (shrink)

It is well known that the process of scientific inquiry, according to Peirce, is drivenby three types of inference, namely abduction, deduction, and induction. What isbehind these labels is, however, not so clear. In particular, the common identificationof “abduction” with “Inference to the Best Explanation” (IBE) begs the question,since IBE appears to be covered by Peirce's concept of induction, not that of abduction.Consequently, abduction ought to be distinguished from IBE, at least on Peirce's account. The main aim of the paper, (...) however, is to show that this distinction is most relevant with respect to current problems in philosophy of science and epistemology (like attempts to supply suitable notions of realism and truth as well as related concepts like coherence and unification). In particular, I also try to show that (and in what way) Peirce's inferential triad can function as a method that ensures both coherence and correspondence. It is in this respect that his careful distinction between abduction and induction (or IBE) ought to be heeded. (shrink)

We explore the grammar of Bayesian confirmation by focusing on some likelihood principles, including the Weak Law of Likelihood. We show that none of the likelihood principles proposed so far is satisfied by all incremental measures of confirmation, and we argue that some of these measures indeed obey new, prima facie strange, antilikelihood principles. To prove this, we introduce a new measure that violates the Weak Law of Likelihood while satisfying a strong antilikelihood condition. We conclude by hinting at some (...) relevant links between the likelihood principles considered here and other properties of Bayesian confirmation recently explored in the literature. (shrink)