Switch to: Citations

Add references

You must login to add references.
  1. Do We Know Whether Researchers and Reviewers are Estimating Risk and Benefit Accurately?Spencer Phillips Hey & Jonathan Kimmelman - 2016 - Bioethics 30 (8):609-617.
    Accurate estimation of risk and benefit is integral to good clinical research planning, ethical review, and study implementation. Some commentators have argued that various actors in clinical research systems are prone to biased or arbitrary risk/benefit estimation. In this commentary, we suggest the evidence supporting such claims is very limited. Most prior work has imputed risk/benefit beliefs based on past behavior or goals, rather than directly measuring them. We describe an approach – forecast analysis – that would enable direct and (...)
    Download  
     
    Export citation  
     
    Bookmark   5 citations  
  • Ethics and epistemology of accurate prediction in clinical research.Spencer Phillips Hey - 2015 - Journal of Medical Ethics 41 (7):559-562.
    All major research ethics policies assert that the ethical review of clinical trial protocols should include a systematic assessment of risks and benefits. But despite this policy, protocols do not typically contain explicit probability statements about the likely risks or benefits involved in the proposed research. In this essay, I articulate a range of ethical and epistemic advantages that explicit forecasting would offer to the health research enterprise. I then consider how some particular confidence levels may come into conflict with (...)
    Download  
     
    Export citation  
     
    Bookmark   2 citations