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Simplicity as Progress: Implications for Fairness in Research With Human Participants

Samia A. Hurst

American Journal of Bioethics 14 (2):40-41 (2014)

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The 50th Anniversary of the Declaration of Helsinki: Progress but Many Remaining Challenges.J. Millum - 2013 - Journal of the American Medical Association 310 (20):2143-44.details Since 1964, through 7 revisions, the World Medical Association’s Declaration of Helsinki has stood as an important statement regarding the ethical principles guiding medical research with human participants. It is consulted by ethics review committees, funders, researchers, and research participants. It has been incorporated into national legislation and is routinely invoked to ascertain the ethical appropriateness of clinical trials. There is much to praise about the revision process and the latest revision, which coincides with the declaration’s 50th anniversary. Nevertheless, the (...) Download Export citation Bookmark 9 citations
Ethical Review of Health Systems Research in Low- and Middle-Income Countries: A Conceptual Exploration.Adnan A. Hyder, Abbas Rattani, Carleigh Krubiner, Abdulgafoor M. Bachani & Nhan T. Tran - 2014 - American Journal of Bioethics 14 (2):28-37.details Given that health systems research involves different aims, approaches, and methodologies as compared to more traditional clinical trials, the ethical issues present in HSR may be unique or particularly nuanced. This article outlines eight pertinent ethical issues that are particularly salient in HSR and argues that the ethical review process should be better tailored to ensure more efficient and appropriate oversight of HSR with adequate human protections, especially in low- and middle-income countries. The eight ethical areas we discuss include the (...) Download Export citation Bookmark 18 citations
Should ethics consultants help clinicians face scarcity in their practice?S. A. Hurst, S. Reiter-Theil, A.-M. Slowther, R. Pegoraro, R. Forde & M. Danis - 2008 - Journal of Medical Ethics 34 (4):241-246.details In an international survey of rationing we have found that European physicians encounter scarcity-related ethical difficulties, and are dissatified with the resolution of many of these cases. Here we further examine survey results to explore whether ethics support services would be potentially useful in addressing scarcity related ethical dilemmas. Results indicate that while the type of help offered by ethics support services was considered helpful by physicians, they rarely referred difficulties regarding scarcity to ethics consultation. We propose that ethics consultants (...) Download Export citation Bookmark 21 citations
Vulnerability in research and health care; describing the elephant in the room?Samia A. Hurst - 2008 - Bioethics 22 (4):191–202.details Despite broad agreement that the vulnerable have a claim to special protection, defining vulnerable persons or populations has proved more difficult than we would like. This is a theoretical as well as a practical problem, as it hinders both convincing justifications for this claim and the practical application of required protections. In this paper, I review consent-based, harm-based, and comprehensive definitions of vulnerability in healthcare and research with human subjects. Although current definitions are subject to critique, their underlying assumptions may (...) Download Export citation Bookmark 100 citations

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