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  1. Vertebrate genome evolution: a slow shuffle or a big bang?Nick G. C. Smith, Robert Knight & Laurence D. Hurst - 1999 - Bioessays 21 (8):697-703.
    In vertebrates it is often found that if one considers a group of genes clustered on a certain chromosome, then the homologues of those genes often form another cluster on a different chromosome. There are four explanations, not necessarily mutually exclusive, to explain how such homologous clusters appeared. Homologous clusters are expected at a low probability even if genes are distributed at random. The duplication of a subset of the genome might create homologous clusters, as would a duplication of the (...)
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