The stochastic phase-space solution of the particle localizability problem in relativistic quantum mechanics is reviewed. It leads to relativistically covariant probability measures that give rise to covariant and conserved probability currents. The resulting particle propagators are used in the formulation of stochastic geometries underlying a concept of quantum spacetime that is operationally based on stochastically extended quantum test particles. The epistemological implications of the intrinsic stochasticity of such quantum spacetime frameworks for microcausality, the EPR paradox, etc., are discussed.