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  1. Epistemic causality and evidence-based medicine.Federica Russo & Jon Williamson - 2011 - History and Philosophy of the Life Sciences 33 (4).
    Causal claims in biomedical contexts are ubiquitous albeit they are not always made explicit. This paper addresses the question of what causal claims mean in the context of disease. It is argued that in medical contexts causality ought to be interpreted according to the epistemic theory. The epistemic theory offers an alternative to traditional accounts that cash out causation either in terms of “difference-making” relations or in terms of mechanisms. According to the epistemic approach, causal claims tell us about which (...)
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  • Mechanisms and the Evidence Hierarchy.Brendan Clarke, Donald Gillies, Phyllis Illari, Federica Russo & Jon Williamson - 2014 - Topoi 33 (2):339-360.
    Evidence-based medicine (EBM) makes use of explicit procedures for grading evidence for causal claims. Normally, these procedures categorise evidence of correlation produced by statistical trials as better evidence for a causal claim than evidence of mechanisms produced by other methods. We argue, in contrast, that evidence of mechanisms needs to be viewed as complementary to, rather than inferior to, evidence of correlation. In this paper we first set out the case for treating evidence of mechanisms alongside evidence of correlation in (...)
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  • The philosophy of evidence-based medicine.Jeremy H. Howick - 2011 - Chichester, West Sussex, UK: Wiley-Blackwell, BMJ Books.
    The philosophy of evidence-based medicine -- What is EBM? -- What is good evidence for a clinical decision? -- Ruling out plausible rival hypotheses and confounding factors : a method -- Resolving the paradox of effectiveness : when do observational studies offer the same degree of evidential support as randomized trials? -- Questioning double blinding as a universal methodological virtue of clinical trials : resolving the Philip's paradox -- Placebo controls : problematic and misleading baseline measures of effectiveness -- Questioning (...)
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  • Social Epistemology: Essential Readings.Alvin I. Goldman & Dennis Whitcomb (eds.) - 2011 - New York: Oxford University Press.
    This volume will be of great interest to scholars and students in epistemology.
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  • (1 other version)Rules and meanings.Mary Douglas - 1973 - [Harmondsworth, Eng.]: Penguin Education.
    First published in 1973, Rules and Meanings is an anthology of works that form part of Mary Douglas' struggle to devise an anthropological modernism conducive to her opposition to reputedly modernizing trends in contemporary society. The collection contains works by Wittgenstein, Schutz, Husserl, Hertz and other continentals. The underlying themes of the anthology are the construction of meaning, the force of hidden background assumptions, tacit conventions and the power of spatial organization to reinforce words. The work serves to complement the (...)
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  • Interpreting causality in the health sciences.Federica Russo & Jon Williamson - 2007 - International Studies in the Philosophy of Science 21 (2):157 – 170.
    We argue that the health sciences make causal claims on the basis of evidence both of physical mechanisms, and of probabilistic dependencies. Consequently, an analysis of causality solely in terms of physical mechanisms or solely in terms of probabilistic relationships, does not do justice to the causal claims of these sciences. Yet there seems to be a single relation of cause in these sciences - pluralism about causality will not do either. Instead, we maintain, the health sciences require a theory (...)
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  • Philosophers on drugs.Bennett Holman - 2019 - Synthese 196 (11):4363-4390.
    There are some philosophical questions that can be answered without attention to the social context in which evidence is produced and distributed.ing away from social context is an excellent way to ignore messy details and lay bare the underlying structure of the limits of inference. Idealization is entirely appropriate when one is essentially asking: In the best of all possible worlds, what am I entitled to infer? Yet, philosophers’ concerns often go beyond this domain. As an example I examine the (...)
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  • Science-Mart: Privatizing American Science.Philip Mirowski - 2011 - Harvard University Press.
    This trenchant study analyzes the rise and decline in the quality and format of science in America since World War II. Science-Mart attributes this decline to a powerful neoliberal ideology in the 1980s which saw the fruits of scientific investigation as commodities that could be monetized, rather than as a public good.
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  • A Cultural Political Economy of Research and Innovation in an Age of Crisis.David Tyfield - 2012 - Minerva 50 (2):149-167.
    Science and technology policy is both faced by unprecedented challenges and itself undergoing seismic shifts. First, policy is increasingly demanding of science that it fixes a set of epochal and global crises. On the other hand, practices of scientific research are changing rapidly regarding geographical dispersion, the institutions and identities of those involved and its forms of knowledge production and circulation. Furthermore, these changes are accelerated by the current upheavals in public funding of research, higher education and technology development in (...)
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  • The Philosophy of Medicine Reborn: A Pellegrino Reader.Edmund D. Pellegrino - 2008 - University of Notre Dame Press. Edited by H. Tristram Engelhardt & Fabrice Jotterand.
    What the philosophy of medicine is -- Philosophy of medicine: should it be teleologically or socially construed? -- The internal morality of clinical medicine: a paradigm for the ethics of the helping and healing professions -- Humanistic basis of professional ethics -- The commodification of medical and health care: the moral consequences of a paradigm shift from a professional to a market ethic -- Medicine today: its identity, its role, and the role of physicians -- From medical ethics to a (...)
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  • The Problem of Intransigently Biased Agents.Bennett Holman & Justin P. Bruner - 2015 - Philosophy of Science 82 (5):956-968.
    In recent years the social nature of scientific inquiry has generated considerable interest. We examine the effect of an epistemically impure agent on a community of honest truth seekers. Extending a formal model of network epistemology pioneered by Zollman, we conclude that an intransigently biased agent prevents the community from ever converging to the truth. We explore two solutions to this problem, including a novel procedure for endogenous network formation in which agents choose whom to trust. We contend that our (...)
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  • The ethos and ethics of translational research.Jane Maienschein, Mary Sunderland, Rachel A. Ankeny & Jason Scott Robert - 2008 - American Journal of Bioethics 8 (3):43 – 51.
    Calls for the “translation” of research from bench to bedside are increasingly demanding. What is translation, and why does it matter? We sketch the recent history of outcome-oriented translational research in the United States, with a particular focus on the Roadmap Initiative of the National Institutes of Health (Bethesda, MD). Our main example of contemporary translational research is stem cell research, which has superseded genomics as the translational object of choice. We explore the nature of and obstacles to translational research (...)
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  • Philosophy of Molecular Medicine: Foundational Issues in Research and Practice.Giovanni Boniolo & Marco J. Nathan (eds.) - 2016 - New York: Routledge.
    _Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice_ aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored (...)
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  • Making Medical Knowledge.Miriam Solomon - 2015 - Oxford: Oxford University Press.
    How is medical knowledge made? There have been radical changes in recent decades, through new methods such as consensus conferences, evidence-based medicine, translational medicine, and narrative medicine. Miriam Solomon explores their origins, aims, and epistemic strengths and weaknesses; and she offers a pluralistic approach for the future.
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  • (1 other version)Experts: which ones should you trust?Alvin I. Goldman - 2011 - In Alvin I. Goldman & Dennis Whitcomb (eds.), Social Epistemology: Essential Readings. New York: Oxford University Press.
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  • Rethinking Value in the Bio-economy: Finance, Assetization, and the Management of Value.Kean Birch - 2017 - Science, Technology, and Human Values 42 (3):460-490.
    Current debates in science and technology studies emphasize that the bio-economy—or, the articulation of capitalism and biotechnology—is built on notions of commodity production, commodification, and materiality, emphasizing that it is possible to derive value from body parts, molecular and cellular tissues, biological processes, and so on. What is missing from these perspectives, however, is consideration of the political-economic actors, knowledges, and practices involved in the creation and management of value. As part of a rethinking of value in the bio-economy, this (...)
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  • Biotechnology: The University-Industrial Complex.Martin Kenney - 1987 - Journal of the History of Biology 20 (3):429-430.
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  • Science, capitalism, and the rise of the “knowledge worker”: The changing structure of knowledge production in the United States. [REVIEW]Daniel Lee Kleinman & Steven P. Vallas - 2001 - Theory and Society 30 (4):451-492.
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  • Bench, bedside, boardroom: negotiating translational gene therapy.Courtney Addison - 2017 - New Genetics and Society 36 (1):22-42.
    This article presents ethnographic material from a London-based group of gene therapists who received the opportunity to trial a device that, its makers claimed, would expedite and improve their cell work. The Vanguard cell processor elicits both enthusiasm and ambivalence from group members, which I seek to understand by examining the group’s current manner of working alongside the device and its purported virtues. I show that cell processing currently involves complex practices of recognition, attention, care, and involvement, which answer to (...)
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