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  1. Can unequal be more fair? Ethics, subject allocation, and randomised clinical trials.A. L. Avins - 1998 - Journal of Medical Ethics 24 (6):401-408.
    Randomised clinical trials provide the most valid means of establishing the efficacy of clinical therapeutics. Ethical standards dictate that patients and clinicians should not consent to randomisation unless there is uncertainty about whether any of the treatment options is superior to the others ("equipoise"). However, true equipoise is rarely present; most randomised trials, therefore, present challenging ethical dilemmas. Minimising the tension between science and ethics is an obligation of investigators and clinicians. This article briefly reviews several techniques for addressing this (...)
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  • Creating false memories.Elizabeth Loftus - manuscript
    When Cool finally realized that false memories had been planted, she sued the psychiatrist for malpractice. In March 1997, after five weeks of trial, her case was settled out of court for $2.4 million. Nadean Cool is not the only patient to develop false memories as a result of questionable therapy. In Missouri in 1992 a church counselor helped Beth Rutherford to remember during therapy that her father, a clergyman, had regularly raped her between the ages of seven and 14 (...)
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  • Participants' understanding of the process of psychological research: Informed consent.Janet L. Brody, John P. Cluck & Alfredo S. Aragon - 1997 - Ethics and Behavior 7 (4):285 – 298.
    Sixty-five undergraduates participating in a wide range of psychological research experiments were interviewed in depth about their research experiences and their views on the process of informed consent. Overall, 32% of research experiences were characterized positively and 41 % were characterized negatively. One major theme of the negative experiences was that experiments were perceived as too invasive, suggesting incomplete explication of negative aspects of research during the informed consent process. Informed consent experiences were viewed positively 80% of the time. However, (...)
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  • The ethics of HIV research in developing nations.David B. Resnik - 1998 - Bioethics 12 (4):286–306.
    This paper discusses a dispute concerning the ethics of research on preventing the perinatal transmission of HIV in developing nations. Critics of this research argue that it is unethical because it denies a proven treatment to placebo‐control groups. Since studies conducted in developed nations would not deny this treatment to subjects, the critics maintain that these experiments manifest a double standard for ethical research and that a single standard of ethics should apply to all research on human subjects. Proponents of (...)
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  • An Inadvertent Breach of Confidentiality.Nancy R. Angoff - 1984 - IRB: Ethics & Human Research 6 (3):5.
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  • Equipoise, Knowledge and Ethics in Clinical Research and Practice.Richard Ashcroft - 1999 - Bioethics 13 (3-4):314-326.
    It is widely maintained that a clinical trial is ethical only if some form of equipoise between the treatments being compared obtains. To be in equipoise between two treatments A and B is to be cognitively indifferent between the statement ‘A is strictly more effective than B’ and its negation. It is natural to claim that equipoise regarding A and B is necessary for randomised assignment to treatments A and B to be beneficent and non‐maleficent and is sufficient for such (...)
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  • At what level of collective equipoise does a clinical trial become ethical?N. Johnson, R. J. Lilford & W. Brazier - 1991 - Journal of Medical Ethics 17 (1):30-34.
    It has often been argued that if a clinician cannot decide which of two treatments to offer, a trial may be ethical, but it is unethical if she/he has a preference. Since individual clinicians usually have a preference, most trials could be judged unethical according to this line of argument. A recent important article in the New England Journal of Medicine argued that individual preferences are not as important as the collective uncertainty of informed clinicians. If clinicians are equally divided, (...)
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  • The Ethics of Involving Psychiatrically Impaired Persons in Research.Evan Gaines DeRenzo - 1994 - IRB: Ethics & Human Research 16 (6):7.
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