Switch to: Citations

Add references

You must login to add references.
  1. [The T complex of the mouse: a failure rich with instruction].M. Morange - 1999 - Revue d'Histoire des Sciences 53 (3-4):521-554.
    Download  
    Translate
     
     
    Export citation  
     
    Bookmark   7 citations  
  • Variation and the Accuracy of Predictions.Michael Kruse - 1997 - British Journal for the Philosophy of Science 48 (2):181-193.
    I present a justification for the intution that more-varied data are more valuable than the same number of less-varied data by showing that the more-varied data help to improve the accuracy of our predictions.
    Download  
     
    Export citation  
     
    Bookmark   7 citations  
  • Varieties of Exploratory Experimentation in Nanotoxicology.Kevin Elliott - 2007 - History and Philosophy of the Life Sciences 29 (3):313 - 336.
    There has been relatively little effort to provide a systematic overview of different forms of exploratory experimentation (EE). The present paper examines the growing subdiscipline of nanotoxicology and suggests that it illustrates at least four ways that researchers can engage in EE: searching for regularities; developing new techniques, simulation models, and instrumentation; collecting and analyzing large swaths of data using new experimental strategies (e.g., computer-based simulation and "high-throughput" instrumentation); and structuring an entire disciplinary field around exploratory research agendas. In order (...)
    Download  
     
    Export citation  
     
    Bookmark   20 citations  
  • On MicroRNA and the Need for Exploratory Experimentation in Post-Genomic Molecular Biology.Richard M. Burian - 2007 - History and Philosophy of the Life Sciences 29 (3):285 - 311.
    This paper is devoted to an examination of the discovery, characterization, and analysis of the functions of microRNAs, which also serves as a vehicle for demonstrating the importance of exploratory experimentation in current (post-genomic) molecular biology. The material on microRNAs is important in its own right: it provides important insight into the extreme complexity of regulatory networks involving components made of DNA, RNA, and protein. These networks play a central role in regulating development of multicellular organisms and illustrate the importance (...)
    Download  
     
    Export citation  
     
    Bookmark   14 citations  
  • Robustness, Discordance, and Relevance.Jacob Stegenga - 2009 - Philosophy of Science 76 (5):650-661.
    Robustness is a common platitude: hypotheses are better supported with evidence generated by multiple techniques that rely on different background assumptions. Robustness has been put to numerous epistemic tasks, including the demarcation of artifacts from real entities, countering the “experimenter’s regress,” and resolving evidential discordance. Despite the frequency of appeals to robustness, the notion itself has received scant critique. Arguments based on robustness can give incorrect conclusions. More worrying is that although robustness may be valuable in ideal evidential circumstances (i.e., (...)
    Download  
     
    Export citation  
     
    Bookmark   38 citations  
  • Themes, Genres and Orders of Legitimation in the Consolidation of New Scientific Disciplines: Deconstructing the Historiography of Molecular Biology.Pninn Abir-Am - 1985 - History of Science 23 (1):73-117.
    Download  
     
    Export citation  
     
    Bookmark   26 citations  
  • Oswald T. Avery and the Copley Medal of the Royal Society.Alexander G. Bearn - 1996 - Perspectives in Biology and Medicine 39 (4):550-554.
    Download  
     
    Export citation  
     
    Bookmark   1 citation  
  • Revisiting the “Quiet Debut” of the Double Helix: A Bibliometric and Methodological Note on the “Impact” of Scientific Publications.Yves Gingras - 2010 - Journal of the History of Biology 43 (1):159-181.
    The object of this paper is two-fold: first, to show that contrary to what seem to have become a widely accepted view among historians of biology, the famous 1953 first Nature paper of Watson and Crick on the structure of DNA was widely cited — as compared to the average paper of the time — on a continuous basis from the very year of its publication and over the period 1953–1970 and that the citations came from a wide array of (...)
    Download  
     
    Export citation  
     
    Bookmark   3 citations  
  • A History of Molecular Biology.Michel Morange & Matthew Cobb - 1999 - Journal of the History of Biology 32 (3):568-570.
    Download  
     
    Export citation  
     
    Bookmark   66 citations  
  • Strategies to Improve the Reliability of a Theory: The Experiment of Bacterial Invasion Into Cultured Epithelial Cells.H. Nederbragt - 2003 - Studies in History and Philosophy of Science Part C 34 (4):593-614.
    An analysis is presented of published methods that have been used by experimenters to justify the reliability of the theory of invasion of microorganisms into cultured cells. The results show that, to demonstrate this invasion, many experimenters used two or more methods that were based on independent technical and theoretical principles, and by doing so improved the reliability of the theory. Subsequently I compare this strategy of 'multiple derivability' with other strategies, discussed in the literature in relation to the mesosome, (...)
    Download  
     
    Export citation  
     
    Bookmark   3 citations  
  • A History of the Inductive Sciences From the Earliest to the Present Time.William Whewell - 1857 - J. W. Parker.
    The curious circumstance that the time of the moon's rotation on her axis is equal to the time of her revolution 30 Syst. du Monde. 8vo. ii. ...
    Download  
     
    Export citation  
     
    Bookmark   22 citations  
  • The Death of Molecular Biology?Michel Morange - 2008 - History and Philosophy of the Life Sciences 30 (1):31 - 42.
    In recent decades the expression "molecular biology" has progressively disappeared from journals, and no longer designates new chairs or departments. This begs the question: does it mean that molecular biology is dead, and has been displaced by new emerging disciplines such as systems biology and synthetic biology? Maybe its reductionist approach to living phenomena has been substituted by one that is more holistic. The situation, undoubtedly, is far less simple. To appreciate better what has happened it is necessary to acknowledge (...)
    Download  
     
    Export citation  
     
    Bookmark   5 citations  
  • Different Methods and Metaphysics in Early Molecular Genetics - A Case of Disparity of Research?U. Deichmann - 2008 - History and Philosophy of the Life Sciences 30 (1):53-78.
    The encounter between two fundamentally different approaches in seminal research in molecular biology-the problems, aims, methods and metaphysics - is delineated and analyzed. They are exemplified by the microbiologist Oswald T. Avery who, in line with the reductionist mechanistic metaphysics of Jacques Loeb, attempted to explain basic life phenomena through chemistry; and the theoretical physicist Max Delbrück who, influenced by Bohr’s antimechanistic views, preferred to explain these phenomena without chemistry. Avery’s and Delbrück’s most important studies took place concurrently. Thus analysis (...)
    Download  
     
    Export citation  
     
    Bookmark   1 citation  
  • The Eighth Day of Creation: Makers of the Revolution in Biology.[author unknown] - 1980 - Journal of the History of Biology 13 (1):141-158.
    Download  
     
    Export citation  
     
    Bookmark   111 citations  
  • Early Responses to Avery Et Al.'S Paper on DNA as Hereditary Material.U. Deichmann - 2004 - Historical Studies in the Physical and Biological Sciences 34 (2):207-232.
    Avery’s et al. ’s 1944 paper provides the first direct evidence of DNA having gene-like properties and marks the beginning of a new phase in early molecular genetics (with a strong focus on chemistry and DNA). The study of its reception shows that on the whole, Avery’s results were immediately appreciated and motivated new research on transformation, the chemical nature of DNA’s biological specificity and bacteria genetics. It shows, too, that initial problems of transferring transformation to other systems and prominent (...)
    Download  
    Translate
     
     
    Export citation  
     
    Bookmark   7 citations