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  1. Explanation: a mechanist alternative.William Bechtel & Adele Abrahamsen - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2):421-441.
    Explanations in the life sciences frequently involve presenting a model of the mechanism taken to be responsible for a given phenomenon. Such explanations depart in numerous ways from nomological explanations commonly presented in philosophy of science. This paper focuses on three sorts of differences. First, scientists who develop mechanistic explanations are not limited to linguistic representations and logical inference; they frequently employ diagrams to characterize mechanisms and simulations to reason about them. Thus, the epistemic resources for presenting mechanistic explanations are (...)
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  • Why is a Wing Like a Spoon? A Pluralist Theory of Function.Beth Preston - 1998 - Journal of Philosophy 95 (5):215.
    Function theorists routinely speculate that a viable function theory will be equally applicable to biological traits and artifacts. However, artifact function has received only the most cursory scrutiny in its own right. Closer scrutiny reveals that only a pluralist theory comprising two distinct notions of function--proper function and system function--will serve as an adequate general theory. The first section describes these two notions of function. The second section shows why both notions are necessary, by showing that attempts to do away (...)
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  • Modeling mechanisms.Stuart Glennan - 2005 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2):443-464.
    Philosophers of science increasingly believe that much of science is concerned with understanding the mechanisms responsible for the production of natural phenomena. An adequate understanding of scientific research requires an account of how scientists develop and test models of mechanisms. This paper offers a general account of the nature of mechanical models, discussing the representational relationship that holds between mechanisms and their models as well as the techniques that can be used to test and refine such models. The analysis is (...)
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  • Plausibility versus richness in mechanistic models.Raoul Gervais & Erik Weber - 2013 - Philosophical Psychology 26 (1):139-152.
    In this paper we argue that in recent literature on mechanistic explanations, authors tend to conflate two distinct features that mechanistic models can have or fail to have: plausibility and richness. By plausibility, we mean the probability that a model is correct in the assertions it makes regarding the parts and operations of the mechanism, i.e., that the model is correct as a description of the actual mechanism. By richness, we mean the amount of detail the model gives about the (...)
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  • Three Problems for the Mutual Manipulability Account of Constitutive Relevance in Mechanisms.Bert Leuridan - 2012 - British Journal for the Philosophy of Science 63 (2):399-427.
    In this article, I present two conceptual problems for Craver's mutual manipulability account of constitutive relevance in mechanisms. First, constitutive relevance threatens to imply causal relevance despite Craver (and Bechtel)'s claim that they are strictly distinct. Second, if (as is intuitively appealing) parthood is defined in terms of spatio-temporal inclusion, then the mutual manipulability account is prone to counterexamples, as I show by a case of endosymbiosis. I also present a methodological problem (a case of experimental underdetermination) and formulate two (...)
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  • Three Kinds of Idealization.Michael Weisberg - 2007 - Journal of Philosophy 104 (12):639-659.
    Philosophers of science increasingly recognize the importance of idealization: the intentional introduction of distortion into scientific theories. Yet this recognition has not yielded consensus about the nature of idealization. e literature of the past thirty years contains disparate characterizations and justifications, but little evidence of convergence towards a common position.
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  • Integrating psychology and neuroscience: functional analyses as mechanism sketches.Gualtiero Piccinini & Carl Craver - 2011 - Synthese 183 (3):283-311.
    We sketch a framework for building a unified science of cognition. This unification is achieved by showing how functional analyses of cognitive capacities can be integrated with the multilevel mechanistic explanations of neural systems. The core idea is that functional analyses are sketches of mechanisms , in which some structural aspects of a mechanistic explanation are omitted. Once the missing aspects are filled in, a functional analysis turns into a full-blown mechanistic explanation. By this process, functional analyses are seamlessly integrated (...)
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  • Function and organization: comparing the mechanisms of protein synthesis and natural selection.Phyllis McKay Illari & Jon Williamson - 2010 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 41 (3):279-291.
    In this paper, we compare the mechanisms of protein synthesis and natural selection. We identify three core elements of mechanistic explanation: functional individuation, hierarchical nestedness or decomposition, and organization. These are now well understood elements of mechanistic explanation in fields such as protein synthesis, and widely accepted in the mechanisms literature. But Skipper and Millstein have argued that natural selection is neither decomposable nor organized. This would mean that much of the current mechanisms literature does not apply to the mechanism (...)
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  • Depth: An Account of Scientific Explanation.Michael Strevens - 2008 - Cambridge: Harvard University Press.
    Approaches to explanation -- Causal and explanatory relevance -- The kairetic account of /D making -- The kairetic account of explanation -- Extending the kairetic account -- Event explanation and causal claims -- Regularity explanation -- Abstraction in regularity explanation -- Approaches to probabilistic explanation -- Kairetic explanation of frequencies -- Kairetic explanation of single outcomes -- Looking outward -- Looking inward.
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  • Making things happen: a theory of causal explanation.James F. Woodward - 2003 - New York: Oxford University Press.
    Woodward's long awaited book is an attempt to construct a comprehensive account of causation explanation that applies to a wide variety of causal and explanatory claims in different areas of science and everyday life. The book engages some of the relevant literature from other disciplines, as Woodward weaves together examples, counterexamples, criticisms, defenses, objections, and replies into a convincing defense of the core of his theory, which is that we can analyze causation by appeal to the notion of manipulation.
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  • Explaining the brain: mechanisms and the mosaic unity of neuroscience.Carl F. Craver - 2007 - New York : Oxford University Press,: Oxford University Press, Clarendon Press.
    Carl Craver investigates what we are doing when we sue neuroscience to explain what's going on in the brain.
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  • The causal and unification approaches to explanation unified—causally.Michael Strevens - 2004 - Noûs 38 (1):154–176.
    The two major modern accounts of explanation are the causal and unification accounts. My aim in this paper is to provide a kind of unification of the causal and the unification accounts, by using the central technical apparatus of the unification account to solve a central problem faced by the causal account, namely, the problem of determining which parts of a causal network are explanatorily relevant to the occurrence of an explanandum. The end product of my investigation is a causal (...)
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  • Functions as based on a concept of general design.Ulrich Krohs - 2009 - Synthese 166 (1):69-89.
    Looking for an adequate explication of the concept of a biological function, several authors have proposed to link function to design. Unfortunately, known explications of biological design in turn refer to functions. The concept of general design I will introduce here breaks up this circle. I specify design with respect to its ontogenetic role. This allows function to be based on design without making reference to the history of the design, or to the phylogeny of an organism, while retaining the (...)
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  • Role functions, mechanisms, and hierarchy.Carl F. Craver - 2001 - Philosophy of Science 68 (1):53-74.
    Many areas of science develop by discovering mechanisms and role functions. Cummins' (1975) analysis of role functions-according to which an item's role function is a capacity of that item that appears in an analytic explanation of the capacity of some containing system-captures one important sense of "function" in the biological sciences and elsewhere. Here I synthesize Cummins' account with recent work on mechanisms and causal/mechanical explanation. The synthesis produces an analysis of specifically mechanistic role functions, one that uses the characteristic (...)
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  • Top-down causation without top-down causes.Carl F. Craver & William Bechtel - 2007 - Biology and Philosophy 22 (4):547-563.
    We argue that intelligible appeals to interlevel causes (top-down and bottom-up) can be understood, without remainder, as appeals to mechanistically mediated effects. Mechanistically mediated effects are hybrids of causal and constitutive relations, where the causal relations are exclusively intralevel. The idea of causation would have to stretch to the breaking point to accommodate interlevel causes. The notion of a mechanistically mediated effect is preferable because it can do all of the required work without appealing to mysterious interlevel causes. When interlevel (...)
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  • Thinking about mechanisms.Peter Machamer, Lindley Darden & Carl F. Craver - 2000 - Philosophy of Science 67 (1):1-25.
    The concept of mechanism is analyzed in terms of entities and activities, organized such that they are productive of regular changes. Examples show how mechanisms work in neurobiology and molecular biology. Thinking in terms of mechanisms provides a new framework for addressing many traditional philosophical issues: causality, laws, explanation, reduction, and scientific change.
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  • Mechanisms, determination and the metaphysics of neuroscience.Patrice Soom - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (3):655-664.
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  • Ascribing Functions to Technical Artefacts: A Challenge to Etiological Accounts of Functions.Wybo Houkes & Pieter E. Vermaas - 2003 - British Journal for the Philosophy of Science 54 (2):261-289.
    The aim of this paper is to evaluate etiological accounts of functions for the domain of technical artefacts. Etiological theories ascribe functions to items on the basis of the causal histories of those items; they apply relatively straightforwardly to the biological domain, in which neo‐Darwinian evolutionary theory provides a well‐developed and generally accepted background for describing the causal histories of biological items. Yet there is no well‐developed and generally accepted theory for describing the causal history of artefacts, so the application (...)
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  • The Explanatory Force of Dynamical and Mathematical Models in Neuroscience: A Mechanistic Perspective.David Michael Kaplan & Carl F. Craver - 2011 - Philosophy of Science 78 (4):601-627.
    We argue that dynamical and mathematical models in systems and cognitive neuro- science explain (rather than redescribe) a phenomenon only if there is a plausible mapping between elements in the model and elements in the mechanism for the phe- nomenon. We demonstrate how this model-to-mechanism-mapping constraint, when satisfied, endows a model with explanatory force with respect to the phenomenon to be explained. Several paradigmatic models including the Haken-Kelso-Bunz model of bimanual coordination and the difference-of-Gaussians model of visual receptive fields are (...)
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  • Mechanisms, determination and the metaphysics of neuroscience.Patrice Soom - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (3):655-664.
    In this paper, I evaluate recently defended mechanistic accounts of the unity of neuroscience from a metaphysical point of view. Considering the mechanistic framework in general , I argue that explanations of this kind are essentially reductive . The reductive character of mechanistic explanations provides a sufficiency criterion, according to which the mechanism underlying a certain phenomenon is sufficient for the latter. Thus, the concept of supervenience can be used in order to describe the relation between mechanisms and phenomena . (...)
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  • Screwdriver Philosophy; Searle's analysis of technical functions.Peter Kroes - 2003 - Techné: Research in Philosophy and Technology 6 (3):131-140.
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  • Ascribing functions to technical artefacts: A challenge to etiological accounts of functions.Pieter E. Vermaas & Wybo Houkes - 2003 - British Journal for the Philosophy of Science 54 (2):261-289.
    The aim of this paper is to evaluate etiological accounts of functions for the domain of technical artefacts. Etiological theories ascribe functions to items on the basis of the causal histories of those items; they apply relatively straightforwardly to the biological domain, in which neo-Darwinian evolutionary theory provides a well-developed and generally accepted background for describing the causal histories of biological items. Yet there is no well-developed and generally accepted theory for describing the causal history of artefacts, so the application (...)
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  • Function Ascription and Explanation: Elaborating an Explanatory Utility Desideratum for Ascriptions of Technical Functions.Dingmar van Eck & Erik Weber - 2014 - Erkenntnis 79 (6):1367-1389.
    Current philosophical theorizing about technical functions is mainly focused on specifying conditions under which agents are justified in ascribing functions to technical artifacts. Yet, assessing the precise explanatory relevance of such function ascriptions is, by and large, a neglected topic in the philosophy of technical artifacts and technical functions. We assess the explanatory utility of ascriptions of technical functions in the following three explanation-seeking contexts: why was artifact x produced?, why does artifact x not have the expected capacity to ϕ?, (...)
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  • Pathways to biomedical discovery.Paul Thagard - 2003 - Philosophy of Science 70 (2):235-254.
    A biochemical pathway is a sequence of chemical reactions in a biological organism. Such pathways specify mechanisms that explain how cells carry out their major functions by means of molecules and reactions that produce regular changes. Many diseases can be explained by defects in pathways, and new treatments often involve finding drugs that correct those defects. This paper presents explanation schemas and treatment strategies that characterize how thinking about pathways contributes to biomedical discovery. It discusses the significance of pathways for (...)
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  • Guest Editorial.John R. Stone & Annette Dula - 2012 - Cambridge Quarterly of Healthcare Ethics 21 (3):307-307.
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  • Mechanisms, Types, and Abstractions.James A. Overton - 2011 - Philosophy of Science 78 (5):941-954.
    Machamer, Darden, and Craver's account of the nature and role of mechanisms in the special sciences has been very influential. Unfortunately, a confusing array of ontic, epistemic, and pragmatic distinctions is required to individuate their mechanisms, mechanism schemata, and mechanism sketches. I diagnose this as a conflation of token-level causal relations with type-level relations. I propose instead that a mechanism is an abstraction that relates entity types and activity types on the model of a directed graph. Mechanisms have an ontic (...)
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  • Mechanisms, malfunctions and explanation in medicine.Mauro Nervi - 2010 - Biology and Philosophy 25 (2):215-228.
    Mechanisms are a way of explaining how biological phenomena work rather than why single elements of biological systems are there. However, mechanisms are usually described as physiological entities, and little or no attention is paid to malfunction as an independent theoretical concept. On the other hand, malfunction is the main focus of interest of applied sciences such as medicine. In this paper I argue that malfunctions are parts of pathological mechanisms, which should be considered separate theoretical entities, conceptually having a (...)
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  • If engineering function is a family resemblance concept: Assessing three formalization strategies.Massimiliano Carrara, Pawel Garbacz & Pieter E. Vermaas - 2011 - Applied ontology 6 (2):141-163.
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  • Can mechanisms really replace laws of nature?Bert Leuridan - 2010 - Philosophy of Science 77 (3):317-340.
    Today, mechanisms and mechanistic explanation are very popular in philosophy of science and are deemed a welcome alternative to laws of nature and deductive‐nomological explanation. Starting from Mitchell's pragmatic notion of laws, I cast doubt on their status as a genuine alternative. I argue that (1) all complex‐systems mechanisms ontologically must rely on stable regularities, while (2) the reverse need not hold. Analogously, (3) models of mechanisms must incorporate pragmatic laws, while (4) such laws themselves need not always refer to (...)
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  • Mechanistic models of population-level phenomena.John Matthewson & Brett Calcott - 2011 - Biology and Philosophy 26 (5):737-756.
    This paper is about mechanisms and models, and how they interact. In part, it is a response to recent discussion in philosophy of biology regarding whether natural selection is a mechanism. We suggest that this debate is indicative of a more general problem that occurs when scientists produce mechanistic models of populations and their behaviour. We can make sense of claims that there are mechanisms that drive population-level phenomena such as macroeconomics, natural selection, ecology, and epidemiology. But talk of mechanisms (...)
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  • Making a Difference.Peter Lipton - 1993 - Philosophica 51.
    An effect is typically explained by citing a cause, but not any cause will do. The oxygen and the spark were both causes of the fire, but normally only the spark explains it. What then distinguishes explanatory from unexplanatory causes? One might attempt to characterise this distinction in terms of intrinsic features of the causes. For example, some causes are changes while others are standing conditions, and one might claim that only the changes explain. Both the spark and the oxygen (...)
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  • Abstraction and the Organization of Mechanisms.Arnon Levy & William Bechtel - 2013 - Philosophy of Science 80 (2):241-261.
    Proponents of mechanistic explanation all acknowledge the importance of organization. But they have also tended to emphasize specificity with respect to parts and operations in mechanisms. We argue that in understanding one important mode of organization—patterns of causal connectivity—a successful explanatory strategy abstracts from the specifics of the mechanism and invokes tools such as those of graph theory to explain how mechanisms with a particular mode of connectivity will behave. We discuss the connection between organization, abstraction, and mechanistic explanation and (...)
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  • Screwdriver Philosophy; Searle's analysis of technical functions.Peter Kroes - 2003 - Techné: Research in Philosophy and Technology 6 (3):131-140.
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  • An ontological model of device function: industrial deployment and lessons learned.Yoshinobu Kitamura, Yusuke Koji & Riichiro Mizoguchi - 2006 - Applied ontology 1 (3):237-262.
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  • Mechanistic Constitution in Neurobiological Explanations.Jens Harbecke - 2010 - International Studies in the Philosophy of Science 24 (3):267-285.
    This paper discusses the constitution relation within the framework of the mechanistic approach to neurobiological explanation. It develops a regularity theory of constitution as an alternative to the manipulationist theory of constitution advocated by some of the proponents of the mechanistic approach. After the main problems of the manipulationist account of constitution have been reviewed, the regularity account is developed based on the notion of a minimal type relevance theory. A minimal type relevance theory expresses a minimally necessary condition of (...)
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  • Discovering Complexity.William Bechtel, Robert C. Richardson & Scott A. Kleiner - 1996 - History and Philosophy of the Life Sciences 18 (3):363-382.
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