The paper presents a subjectivist interpretation of Protagoras’ man-measure fragment, by explaining some key terms (‘all things’, ‘measure’, ‘man’) and reconstructing his ontological, epistemological and anthropological views. The argument uses other fragments and testimonies of Protagoras as well as intertextual allusions to previous authors (especially Anaxagoras) and instances of reception of Protagoras by Plato, Aristotle and Isocrates which are particularly used here for the first time in order to interpret the man-measure fragment. It is argued that Protagoras denied metaphysical speculation (...) and preferred human knowledge based on subjective perception and made plausible by intersubjective discourse. (shrink)