In several counties, Vitex negundo have been claimed to have anti-inflammatory, analgesic, and antioxidant activities. It's frequently used in folk medicine for the treatment of various pain disorders. The methanol extract of Vitex negundo leaves was studied for its biological effects. To investigate different biological exertions of the methanol extract of Vitex negundo, the leaf extracts were obtained with pure methanol. In-vitro anti-oxidant activity was resolved using a DPPH radical scavenging assay. A clot lysis test was used to assess the (...) thrombolytic activity. Antiproliferative effects of DMSO Vitex negundo in cell lines acquired from human cervix adenocarcinoma (HeLa cells). Using the brine shrimp lethality bioassay method, the plant extracts were evaluated for cytotoxic action. LC50 values were determined through probit analysis of mortality percentages. In hole cross-test and open-field test, neuropharmacological activities of mice were assessed in mice. The findings revealed that Vitex negundo leaf extract possessed antioxidant effects, streptokinase exposed significant clot lysis and human cervix adenocarcinoma cells demonstrated mild cervical antiproliferative activity. Significant neuropharmacological action (antidepressant and anxiolytic) and cytotoxic action were shown by the methanol extract of Vitex negundo leaves. (shrink)

his study explores Pynchon’s mammoth novel, Against the Day, in terms of the minor practice of language as proposed by Deleuze and Guattari in their book Kafka: Toward a Minor Literature, which opens up new possibilities for literary criticism. With his idiosyncratic, intensive, and inventive practice of language, Pynchon shatters the already existing notions of appropriate and homogenizing forms of major language. The novel demystifies the language’s institutionalized system of signification and defies identifiable decipherable meaning in many ways, such as (...) covert and overt deterritorialization of language, escape from “territorial” and “representational” language, defiance of signification, neutralization of sense, asyntactical language, phantasmagorical and absurd tales, quizzical jokes, silly songs, and asubjective free indirect narration. Against the Day’s practice of language prefers the territory of asubjective insignification to subjective, symbolic, and signifying usage of language so as to dismantle the territory of representation; thus, it pushes the major language towards or even out of its limits. (shrink)

In Against the Day, Pynchon is obsessed with twoness, double worlds, as well as dual realities, and like Deleuze’s concept of repetition, these duplications and twinships are not merely repetition of the same, rather they allow for creativity, reinvention, and becoming. Pynchon’s duplication of fictional and spectral characters intends to critique the notion of identity as does Deleuzian concept of repetition. Not attached to the representational concept of identity as the recurrence of the same, Pynchon’s duplications decenter the transcendental concept (...) in favor of a perpetual becoming and reproduces difference and singularity. Like Deleuze, Pynchon eschews an identity that is always guaranteed, and shows that the repetition of an object or a subject is not the recurrence of the original self-identical object or person. Moreover, Iceland spar, the mystifying calcite, with its doubling effect provides the reader with a view of a world beyond the ordinary, actual world, which is quite similar to what Pynchon’s novel does per se. (shrink)

The bruxism is a medical sleep syndrome it is the remedial span for crushing the tines and gritting the jowl. Human rarely chore their tines and jowl, slightly than crushing their teeth lacking it producing any signals. The symptoms of bruxism are arduousness in the jowl joint, breakable teeth, headache, earache and difficulty in open in mouth etc. The causes of bruxism are snooze sickness, pressure and nervousness. The REM is a rapid eye movement it's a stages of sleep. The (...) EEG signal are used in the measurement of neuron, the alpha, beta, gamma, theta and delta wave are used in the prognostic of bruxism syndrome. It's used in MATLAB coding by the six steps in prognostic in bruxism. Md Belal Bin Heyat | Faijan Akhtar | Shadab Azad "Comparative Analysis of Original Wave & Filtered Wave of EEG signal Used in the Prognostic of Bruxism medical Sleep syndrome" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-1 | Issue-1 , December 2016,. (shrink)