10 found
Order:
Disambiguations
Giovanni De Grandis [9]Giovanni De De Grandis [1]
See also
Giovanni De Grandis
University College London
  1. Grand Challenges and Small Steps. Introduction to the Special Issue 'Interdisciplinary Integration: The Real Grand Challenge for the Life Sciences?'.Giovanni De Grandis & Sophia Efstathiou - 2016 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 56:39-47.
    This collection addresses two different audiences: 1) historians and philosophers of the life sciences reflecting on collaborations across disciplines, especially as regards defining and addressing Grand Challenges; 2) researchers and other stakeholders involved in cross-disciplinary collaborations aimed at tackling Grand Challenges in the life and medical sciences. The essays collected here offer ideas and resources both for the study and for the practice of goal-driven cross-disciplinary research in the life and medical sciences. We organise this introduction in three sections. The (...)
    Download  
     
    Export citation  
     
    Bookmark   2 citations  
  2. Practical Integration: The Art of Balancing Values, Institutions and Knowledge. Lessons From the History of British Public Health and Town Planning.Giovanni De Grandis - 2016 - Studies in History and Philosophy of Science Part C 56:92-105.
    The paper uses two historical examples, public health (1840-1880) and town planning (1945-1975) in Britain, to analyse the challenges faced by goal-driven research, an increasingly important trend in science policy, as exemplified by the prominence of calls for addressing Grand Challenges. Two key points are argued. (1) Given that the aim of research addressing social or global problems is to contribute to improving things, this research should include all the steps necessary to bring science and technology to fruition. This need (...)
    Download  
     
    Export citation  
     
    Bookmark  
  3.  81
    Conceptual and Terminological Confusion Around Personalised Medicine: A Coping Strategy.Giovanni De Grandis & Vidar Halgunset - 2016 - BMC Medical Ethics 17 (1):1-12.
    The idea of personalised medicine (PM) has gathered momentum recently, attracting funding and generating hopes as well as scepticism. As PM gives rise to differing interpretations, there have been several attempts to clarify the concept. In an influential paper published in this journal, Schleidgen and colleagues have proposed a precise and narrow definition of PM on the basis of a systematic literature review. Given that their conclusion is at odds with those of other recent attempts to understand PM, we consider (...)
    Download  
     
    Export citation  
     
    Bookmark   2 citations  
  4.  7
    The Promise and Perils of Biotech in Personalised Healthcare. Can New Regulatory Pathways Protect the Vulnerable?Giovanni De Grandis - 2018 - Risk 32 (Winter 2008):20-23.
    The paper discusses some of the implications of regulatory innovation in the area of advanced biological therapies and personalised medicine. Benefits, risks and trade-offs are highlighted.
    Download  
     
    Export citation  
     
    Bookmark  
  5. Conoscenza, azione e antropologia nella filosofia di John Rawls.Giovanni De Grandis - 2003 - Problemata. Quaderni di Filosofia 3:81-139.
    Download  
    Translate
     
     
    Export citation  
     
    Bookmark  
  6.  46
    Harvesting the Promise of AOPs: An Assessment and Recommendations.Annamaria Carusi, Mark R. Davies, Giovanni De De Grandis, Beate I. Escher, Geoff Hodges, Kenneth M. Y. Leung, Maurice Wheelan, Catherine Willet & Gerald T. Ankley - 2018 - Science of the Total Environment 628:1542-1556.
    The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals. The AOP framework and associated knowledgebases (KBs) have received significant attention and use in the regulatory toxicology community. However, it is increasingly apparent that the potential stakeholder community for the AOP concept and AOP KBs is broader than scientists and regulators directly involved in chemical safety assessment. In this paper we (...)
    Download  
     
    Export citation  
     
    Bookmark  
  7. Pandemics - Background Paper.Giovanni De Grandis & Jasper Littmann - 2011 - Forward Look Archive.
    The background paper provides an introduction to the concept of pandemics and to the ethical and political issues related with pandemic preparedness.
    Download  
     
    Export citation  
     
    Bookmark  
  8. Measuring Openness and Evaluating Digital Academic Publishing Models: Not Quite the Same Business.Giovanni De Grandis & Yrsa Neuman - 2014 - The Journal of Electronic Publishing 17 (3).
    In this article we raise a problem, and we offer two practical contributions to its solution. The problem is that academic communities interested in digital publishing do not have adequate tools to help them in choosing a publishing model that suits their needs. We believe that excessive focus on Open Access (OA) has obscured some important issues; moreover exclusive emphasis on increasing openness has contributed to an agenda and to policies that show clear practical shortcomings. We believe that academic communities (...)
    Download  
     
    Export citation  
     
    Bookmark  
  9.  40
    Pharmacogenomic Inequalities: Strategies for Justice in Biomedical Research and Healthcare.Giovanni De Grandis - 2017 - Diametros 51:153-172.
    The paper discusses the possibility that the benefits of pharmacogenomics will not be distributed equally and will create orphan populations. I argue that since these inequalities are not substantially different from those produced by ‘traditional’ drugs and are not generated with the intention to discriminate, their production needs not be unethical. Still, the final result is going against deep-seated moral feelings and intuitions, as well as broadly accepted principles of just distribution of health outcomes and healthcare. I thus propose two (...)
    Download  
     
    Export citation  
     
    Bookmark  
  10.  69
    Rescuing Solidarity From Its Carers. A Response to Professor ter Meulen.Giovanni De Grandis - 2015 - Diametros 43:28-43.
    The paper points out three serious problems in Ruud ter Meulen’s view of solidarity and of its role in healthcare ethics. First, it is not clear whether and to what extent ter Meulen expects normative concepts to be rooted in existing social practices: his criticism of liberal theories of justice seems to imply a different view on this issue than his implicit assumption that normative concepts are independent from social and historical trends. Second, it is not clear at which level (...)
    Download  
     
    Export citation  
     
    Bookmark