In quantum mechanics, quantum nonseparability is at the core of philosophical debates regarding its meaning. In the context of the process matrix formalism, causal nonseparability characterises quantum processes (connecting the inputs and outputs of different local quantum operations) that are incompatible with any definite causal structure among interacting parties. One talks about indefinite causal orders. A famous example of causally nonseparable processes is called the quantum switch (QS). It is extensively studied in the literature in virtue of its simple architecture (...) and its various implementations in laboratories.The present work will discuss the possible interpretations of the QS's causal nonseparability under the assumption that causal nonseparability is seen as pointing towards novel objective features of nature.It was first defended that a scientific realist approach towards the process matrix formalism, which is an operational theory generalising quantum mechanics, was as much legitimate as any possible antirealist reading, contrary to certain views found in the literature. The reason is that operational formalisms are ontologically and epistemically neutral.From there, the theoretical concepts of interest, namely causal nonseparability and its model-independent counterpart called noncausality, were analysed in more details, in order to highlight in what sense they are distinct from the standard notions of quantum nonseparability and nonlocality in quantum mechanics.The discussion then focused on noncausality. It was argued that noncausality has a strong connection with a notion of temporal nonlocality. In the same way that Bell nonlocality is given different underlying explanations depending on the details of the chosen quantum mechanics' account, noncausality pointing towards temporal nonlocality can be given a variety of underlying descriptions depending on the exact way to interpret the process matrix formalism.The last chapter focused precisely on this particular point, namely on the various ways to understand process matrices and causal nonseparability in a realist context. In order to explore the potential impact of causal nonseparability on spacetime,we shifted from the notion of (indefinite) causal structure to (indefinite) spatiotemporal ones. This shift was allowed under a set of reasonable assumptions regarding the properties of a physical spacetime manifold and the connection between an operational and relativistic notions of causal relations.While different readings were suggested for indefiniteness of spatiotemporal relations, we insisted in particular on an objective understanding appealing to the concept of metaphysical indeterminacy. It was argued that such an approach could prove useful in a more general theoretical context such as quantum gravity, while being already partly supported in standard quantum mechanics. (shrink)