Underwater Wireless Sensor Networks (UWSNs) are pivotal for various applications, including oceanographic data collection, environmental monitoring, and naval operations. However, the harsh underwater environment poses challenges in designing efficient routing protocols, especially concerning energy consumption and data transmission reliability. This paper proposes an optimized depth-based routing protocol for energy-aware data transmission in UWSNs, focusing on minimizing energy usage while ensuring robust data delivery. The protocol dynamically adjusts transmission power based on node depth and residual energy, reducing communication overhead and prolonging (...) network lifetime. (shrink)

The rapid advancement of artificial intelligence (AI) technologies has revolutionized various industries, including the realm of education and career guidance. This project endeavors to harness the power of AI to develop a sophisticated career guidance application that offers personalized and effective recommendations to students and job seekers. The primary objective of this project is to address the limitations of traditional career guidance methods, which often lack customization and fail to adapt to individual preferences, skills, and aspirations. Through the integration of (...) AI algorithms, NLP techniques, and ML models, our application aims to provide accurate interest assessments, skill matching, and tailored educational pathways. (shrink)

The health of plants plays a crucial role in ensuring agricultural productivity and food security. Early detection of plant diseases can significantly reduce crop losses, leading to improved yields. This paper presents a novel approach for plant disease recognition using deep learning techniques. The proposed system automates the process of disease detection by analyzing leaf images, which are widely recognized as reliable indicators of plant health. By leveraging convolutional neural networks (CNNs), the model identifies various plant diseases with high accuracy. (...) The experimental setup includes a dataset consisting of healthy and diseased leaf images of different plant species. The dataset is preprocessed to remove noise and augmented to address the issue of class imbalance. The CNN model is then trained, validated, and tested on this dataset. (shrink)

I. EXECUTIVE SUMMARY The MRCT Center Post-trial Responsibilities: Continued Access to an Investigational Medicine Framework outlines a case-based, principled, stakeholder approach to evaluate and guide ethical responsibilities to provide continued access to an investigational medicine at the conclusion of a patient’s participation in a clinical trial. The Post-trial Responsibilities (PTR) Framework includes this Guidance Document as well as the accompanying Toolkit. A 41-member international multi-stakeholder Workgroup convened by the Multi-Regional Clinical Trials Center of Brigham and Women’s Hospital and Harvard University (...) (MRCT Center) developed this Guidance and Toolkit. Project Motivation A number of international organizations have discussed the responsibilities stakeholders have to provide continued access to investigational medicines. The World Medical Association, for example, addressed post-trial access to medicines in Paragraph 34 of the Declaration of Helsinki (WMA, 2013): “In advance of a clinical trial, sponsors, researchers and host country governments should make provisions for post-trial access for all participants who still need an intervention identified as beneficial in the trial. This information must also be disclosed to participants during the informed consent process.” This paragraph and other international guidance documents converge on several consensus points: • Post-trial access (hereafter referred to as “continued access” in this Framework [for terminology clarification – see definitions]) is the responsibility of sponsors, researchers, and host country governments; • The plan for continued access should be determined before the trial begins, and before any individual gives their informed consent; • The protocol should delineate continued access plans; and • The plan should be transparent to potential participants and explained during the informed consent process. -/- However, there is no guidance on how to fulfill these responsibilities (i.e., linking specific responsibilities with specific stakeholders, conditions, and duration). To fill this gap, the MRCT Center convened a working group in September of 2014 to develop a framework to guide stakeholders with identified responsibilities. This resultant Framework sets forth applicable principles, approaches, recommendations and ethical rationales for PTR regarding continued access to investigational medicines for research participants. (shrink)