It is widely believed to be permissible for a physician to discontinue any treatment upon the request of a competent patient. Many also believe it is never permissible for a physician to intentionally kill a patient. I argue that the prospect of deactivating a patient’s artificial heart presents us with a dilemma: either the first belief just mentioned is false or the second one is. Whichever horn of the dilemma we choose has significant implications for contemporary medical ethics.

In our article (Zawadzki and Adamczyk 2021), we analyzed threats that novel memory modifying interventions may pose in the future. More specifically, we discussed how optogenetics’ potential for reversible erasure/deactivation of memory “may impact authenticity by producing changes at different levels of personality.” Our article has received many thoughtful open peer commentaries for which we would like to express our great appreciation. We have identified two main threads of objections. They are related to the potential applicability of optogenetics as (...) a therapeutic memory modification technology (MMT) in humans—applicability thread, and the normative value of authenticity, that is, the assumption that preserving authenticity is valuable (either in general or in the particular approach we adopted)—normative thread. Both of these threads concern fundamental issues: The former deals with the scientific credibility of the case vignette on which our discussion is based, and the latter deals with the normative weight of our considerations. We think that addressing both of them can be instructive in a broader context as they reflect a more general disagreement among neuroethicists about the very purpose and method of our discipline. (shrink)

Two lines of evidence indicate that there exists a reciprocal inhibitory relationship between opposed brain networks. First, most attention-demanding cognitive tasks activate a stereotypical set of brain areas, known as the task-positive network and simultaneously deactivate a different set of brain regions, commonly referred to as the task negative or defaultmode network. Second, functional connectivity analyses show that these same opposed networks are anti-correlated in the resting state. Wehypothesize that these reciprocally inhibitory effects reflect two incompatible cognitive modes, each of (...) which may be directed towards understanding the external world. Thus, engaging onemode activates one set of regions and suppresses activity in the other.Wetest this hypothesis by identifying two types of problem-solving task which, on the basis of prior work, have been consistently associated with the task positive and task negative regions: tasks requiring social cognition, i.e., reasoning about the mental states of other persons, and tasks requiring physical cognition, i.e., reasoning about the causal/mechanical properties of inanimate objects. Social and mechanical reasoning tasks were presented to neurologically normal participants during fMRI. Each task type was presented using both text and video clips. Regardless of presentation modality, we observed clear evidence of reciprocal suppression: social tasks deactivated regions associated with mechanical reasoning and mechanical tasks deactivated regions associated with social reasoning. These findings are not explained by self-referential processes, task engagement, mental simulation,mental time travel or external vs. internal attention, all factors previously hypothesized to explain default mode network activity. Analyses of resting state data revealed a close match between the regions our tasks identified as reciprocally inhibitory and regions of maximal anti-correlation in the resting state. These results indicate the reciprocal inhibition is not attributable to constraints inherent in the tasks, but is neural in origin. Hence, there is a physiological constraint on our ability to simultaneously engage two distinct cognitive modes. Furtherwork is needed tomore precisely characterize these opposing cognitive domains. (shrink)

Cognitive theories claim, whereas non-cognitive theories deny, that cognitive access is constitutive of phenomenology. Evidence in favor of non-cognitive theories has recently been collected by Block and is based on the high capacity of participants in partial-report experiments compared to the capacity of the working memory. In reply, defenders of cognitive theories have searched for alternative interpretations of such results that make visual awareness compatible with the capacity of the working memory; and so the conclusions of such experiments remain controversial. (...) Instead of entering the debate between alternative interpretations of partial-report experiments, this paper offers an alternative line of research that could settle the discussion between cognitive and non-cognitive theories of consciousness. Here I relate the neural correlates of cognitive access to empirical research into the neurophysiology of dreams; cognitive access seems to depend on the activity of the dorsolateral prefrontal cortex. However, that area is strongly deactivated during sleep; a period when we entertain conscious experiences: dreams. This approach also avoids the classic objection that consciousness should be inextricably tied to reportability or it would fall outside the realm of science. (shrink)

For nearly two decades, ethicists have expressed concerns that the further development and use of memory modification technologies (MMTs)—techniques allowing to intentionally and selectively alter memories—may threaten the very foundations of who we are, our personal identity, and thus pose a threat to our well-being, or even undermine our “humaneness.” This paper examines the potential ramifications of memory-modifying interventions such as changing the valence of targeted memories and selective deactivation of a particular memory as these interventions appear to be (...) at the same time potentially both most promising clinically as well as menacing to identity. However, unlike previous works discussing the potential consequences of MMTs, this article analyzes them in the context of the narrative relational approach to personal identity and potential issues related to autonomy. I argue that such a perspective brings to light the ethical aspects and moral issues arising from the use of MMTs that have been hidden from previously adopted approaches. In particular, this perspective demonstrates how important the social context in which an individual lives is for the ethical evaluation of a given memory-modifying intervention. I conclude by suggesting that undertaking memory modifications without taking into account the social dimension of a person’s life creates the risk that she will not be able to meet one of the basic human needs—the autonomous construction and maintenance of personal identity. Based on this conclusion, I offer some reflections on the permissibility and advisability of MMTs and what these considerations suggest for the future. (shrink)

Higher-Order Thought (HOT) theories of consciousness maintain that the kind of awareness necessary for phenomenal consciousness depends on the cognitive accessibility that underlies reporting. -/- There is empirical evidence strongly suggesting that the cognitive accessibility that underlies the ability to report visual experiences depends on the activity of the dorsolateral prefrontal cortex (dlPFC). This area, however, is highly deactivated during the conscious experiences we have during sleep: dreams. HOT theories are jeopardized, as I will argue. I will briefly present HOT (...) theories in the first section. Section 2 offers empirical evidence to the effect that the cognitive accessibility that underlies the ability to report depends on the dorsolateral prefrontal cortex: dlPFC is the neural correlate of HOTs. Section 3 shows the evidence we have of the deactivation of this brain area during dreams and, in section 4, I present my argument. Finally, I consider and rejoin two possible replies that my opponent can offer: the possibility of an alternative neural correlate of HOTs during dreams and the denial that we have phenomenally conscious experiences during sleep. (shrink)

This chapter is an overview of Giorgio Agamben's engagement, in the Homo Sacer series (1995–2014), with Aristotelian philosophy. It specifically studies Agamben's attempt to deconstruct two Aristotelian conceptual oppositions fundamental for the Western tradition of political thought: (1) that between the bare fact of being alive and "qualified" living (associated by Agamben with an alleged distinction between zōē and bios) and (2) that between potentiality (dynamis) and actuality (energeia). Agamben's concept of form-of-life (forma-di-vita), a life that is never "bare" but (...) always in the process of qualifying itself, is designed to deactivate and overcome these distinctions. In the final volume of the series, The Use of Bodies (2014), this is done with the help of the Aristotelian concepts of use (chrēsis) and habit (hexis). (shrink)

The manuscript presents a summary of the results of the linguistic semantics study of Covid-19 related quarantine. Research conducted on a sample of Russian speaking Ukrainians. Found content and structure of the respective discursive field. Described features of inter-discourse connections. Established that the actualization of some discourses is accompanied by the deactivation of others, what makes quarantine semantics biased. Also, it was suggested that some of the discourses are indirectly positively associated and form the semantic core of the quarantine (...) concept. (shrink)

The broadcast nature of communication in transmission media has driven the rise of network coding’s popularity in wireless networks. Numerous benefits arise from employing network coding in multi-hop wireless networks, including enhanced throughput, reduced energy consumption, and decreased end-to-end delay. These advantages are a direct outcome of the minimized transmission count. This paper introduces a comprehensive framework to employ network coding in these networks. It refines decision-making at coding and decoding nodes simultaneously. The coding-nodes employ optimal stopping theory to find (...) optimal moments for packet transmission. Meanwhile, the decoding-nodes dynamically decide, through SMDP (Semi Markov Decision Process) problem formulation, whether to conserve energy by deactivating radio units or to stay active for improved coding by overhearing packets. The proposed framework, named ENCODE, enables nodes to learn how and when to use network coding over time. Simulation results compare its performance with existing approaches. Our simulation results shed new light on when and how to use network coding in wireless multi-hop networks more effectively. (shrink)

This essay examines Primo Levi’s atheism. First, I reconstruct Levi’s reflection on chance in "If This Is a Man" as the core of his universalist understanding of the concentrationary experience. In Levi, fortune – a moralizing resignification of chance - represents the contingency that decides upon a human existence dramatically marked by the fundamental inequality between the drowned and the saved. This is the philosophical background of chapter October 1944, where Levi outlines his first attempt of anti-theodicy, from which he (...) sketches the basis of his ethics of fortune. Second, by extending the chronological scope of my analysis up to the 1980s, I define Levi’s philosophical atheism in terms of social anti-theodicy. I show how the question of inequality, natural and political, constitutes the supreme contradiction for a theistic understanding of Providence, whose intervention in the human world tends to increase the onto-anthropological structures of political domination. Finally, I examine the 1971 short story “The brokers”, (“Procacciatori d’affari”) in which Levi outlines the conceptual frame of an ethics of fortune, in which the choice of chance constitutes the fundamental egalitarian act to deactivate the theological and political dispositive of privilege. (shrink)

This article has been written about the explanation of the scientific affair. There are the philosophical circles that a philosopher must consider their approaches. Postmodern thinkers generally refuse the universality of the rational affair. They believe that the experience cannot reach general knowledge. They emphasize on the partial and plural knowledge. Any human being has his knowledge and interpretation. The world is always becoming. Diversity is an inclusive epistemological principle. Naturally, in such a state, the scientific activity is a non-sense (...) process. The postmodern world is a post-scientific world. Another collection of approaches to science belongs to the analytical philosophy. The main part of analytical philosophy context centers around language. Language is the center of the world. We can study the world through language. Language is the possibility of knowledge. If we overcome the language games, we can study the world accurately. Generally, at present, it seems that the rational thoughts are marginal points in the sea of irrationality. We can probably talk about an anarchistic epistemological situation. Another issue is the role of observation to form a scientific activity. In this situation, the question is whether the observation is the technique of gathering information or the final reference of original scientific analysis. In relation to this issue, the confrontation of science with the families and the categories of the objects is the main problem. For more than two thousand years, the totalitarian heritage of the Aristotelian logic has been the guideline of categorizations for the human being. In order to reach an inclusive and applicable result, we should categorize everything; but it is not really known that if the method of the world categorization is the same or not. The accordance of the conceptual categories with their extensions in the world is one of the main problems which has malfunctioned the scientific system. It is better to say that it has deactivated science. Moreover, there are many interpretations for each event based on its occurrence conditions. For example, consider a fever; In order to diagnose its cause, the most significant factor is the role of a physician. There is no sense in saying that the observation has diagnosed the cause of the fever. This is the observer that plays a determinative role. Another problem is the disputes between realism and instrumentalism. Instrumentalists believe that to form a theory, the concepts are just the tools of scientific researches. Based on realism, but we confront the concepts in the original way. This chaos causes the scientific system to collapse. Now the question is what the solution is. I would like to propose my scheme that is constructed based on a main principle: there is no occurrence in the world unless we can trace the effect of consciousness back in that occurrence. In other words, there is no accident in the world. One can argue that it is the main problem that the effects of consciousness ---if there is such a concept--- is not traceable in the world. An immediate response to this problem is an inefficient technique . The observation is a technique . It is not the method of interpretation. Some people argue that the empirical approach cannot lead us to an authentic criterion to know the world. Because there is no criterion for truth, and if there is probably such a criterion, we can obtain it via several ways. The solution to the first problem is simple. Any occurrence is a truth; even we suppose it as a partial truth. Therefore we can say we face a multi-facial world. It can be the solution of the second problem: if consciousness is essentially the origin of the world and all occurrences, we face consciousness as a unique truth; even its creations contradict each other. If there is no consciousness as a creator of the world and we cannot trace it back in all existents, then what should we do? If there is consciousness, why its creations contradict each other. Since consciousness is a will, it is able to decide in any situation it intends. The issue of contradictory consciousness intentions has a teleological aspect. We cannot judge its teleological substance at present. If we are able to believe that there is no consciousness at all, it will contradict the main practical principle in our lives. Every action that we take in our lives is conjoined with consciousness. We learn many things from many sources. The substance of our instincts and emotions can be questioned. It is true that, infact we cannot analyze our instincts and emotions, but we can discuss explicitly about the rational elements of the instincts. What are these elements? These elements are the quality of their appearance. The quality of instinct appearance is different among beings. The strength and the depth and length of these irrational qualities are different in all beings. What factors or factor cause the differences among these aspects? There is certainly a determinative factor. The same factor which determines the occurrence of any event. Even if we believe in partial knowledge, we must accept the confrontation of the occurrences. Thus it is not possible to refuse the occurrences as the reference unit of knowledge. In spite of the difference, every occurrence, even as a single occurrence, happens and we can regard it as the reference unit of knowledge. Then we can consider every occurrence as an occurred object. When an occurrence happens, then it is a determined object. Everywhere there is a determination, there is certainly a determiner. Why do not we encounter a multi-determinative consciousness? Because there are a few aspects of the unique super-consciousness. These aspects are motion and growth and the amount of constituent material in every being. In all over the world, the difference in these factors creates all differences. Thus we do not encounter the plural consciousness. Is the world birth accidental? Infact, there is no accident. The accident has no meaning in the world. As explained above, the constructing element of the world is the occurrence. An occurrence can be analyzed. Therefore, we should not talk about the accident until we are not able to analyze all phenomena. We can look at every subject from different points of view at present. Thus there is theoretically no possibility to say that a certain matter is the consequence of the accident. The accident is a popular and inexact concept that has no philosophical content. Moreover, the definition of consciousness versus its contradiction causes the collapse of all epistemological axioms. We can ask why we must not define other logical principles against their contradictions. Thinkers who deny the role of logic usually ignore the role of logic. They have not been able to deny the logical function to form an epistemological system because it is not an easy task. In this article some other issues were discussed, such as the consideration of restriction as a stable and firm foundation of knowledge instead of the Descartes cogito. In addition to these philosophical points some other issues were propounded such as the role of instrumental mechanism to form the new science and the great alterations in philosophy and history of Europe. Many issues threaten human civilization. The only way to deal with such threats is certainly to use scientific facilities. The scientific possibilities undoubtedly come from a complete and inclusive scientific theory. The present article is an attempt to explain the scientific affair in order to develop human achievement, however small. -/- . (shrink)