The introduction of respiratory machines in the 1950s may have saved the lives of many, but it also challenged the notion of death itself. This development endowed “machines” with the power to form a unique ontological creature: a live body with a “dead” brain. While technology may be blamed for complicating things in the first place, it is also called on to solve the resulting quandaries. Indeed, it is not the birth of the “brain-dead” that concerns us most, but rather (...) its association with a web of epistemological and ethical considerations, where technology plays a central role. The brain death debate in Israel introduces highly sophisticated religious thought and authoritative medical expertise. At focus are the religious acceptance and rejection of brain death by a technologically savvy group of rabbis whose religious doctrine––along with a particular form of religious reasoning––is used to support the truth claims made from the scientific community but challenge the ways in which they are made credible. In our case, brain death as “true” death is made religiously viable with the very use of technological apparatus and scientific rhetoric that stand at the heart of the scientific ethos. (shrink)

This article analyzes how the medical gaze made possible by MRI operates in radiological laboratories. It argues that although computer-assisted medical imaging technologies such as MRI shift radiological analysis to the realm of cyborg visuality, radiological analysis continues to depend on visualization produced by other technologies and diagnostic inputs. In the radiological laboratory, MRI is used to produce diverse sets of images of the internal parts of the body to zero in and visually extract the pathology. Visual extraction of pathology (...) becomes possible, however, because of the visual training of the radiologists in understanding and interpreting anatomic details of the whole body. These two levels of viewing constitute the bifocal vision of the radiologists. To make these levels of viewing work complementarily, the body, as it is presented in the body atlases, is made notational. (shrink)

This paper follows the history of an object. The purpose of doing so is to come to terms with a distinctive kind of research object – which we are calling a ‘test object’ – as well as to chronicle a significant line of research and technology development associated with the broader nanoscience/nanotechnology movement. A test object is one of a family of epistemic things that makes up the material culture of laboratory science. Depending upon the case, it can have variable (...) shadings of practical, mathematical and epistemic significance. Clear cases of test objects have highly regular and reproducible visible properties that can be used for testing instruments and training novices. The test object featured in this paper is the silicon 7×7, a particular surface configuration of silicon atoms. Research on this object over a period of several decades has been closely bound up with the development of novel instruments for visualizing atomic structures. Despite having little direct commercial value, the Si 7×7 also has been a focal object for the formation of a research community bridging industry and academia. It exhibits a complex structure that became a sustained focus of observation and modelling. Our study follows shifts in the epistemic status of the Si 7×7, and uses it to re-examine familiar conceptions of representation and observation in the history, philosophy and social study of science. (shrink)

Researchers in science and technology studies appear to be more concerned with descriptions and explanations of social phenomena than with the potential applications of their findings. Science and technology studies should strive to change society by contributing to the design of learning environments that form future generations of producers and consumers of scientific and technological knowledge. In this article, the authors illustrate how they used research findings from science and technology studies to design alternative learning environments and summarize their principal (...) findings from six years of ethnographic research in these learning environments. They conclude by pointing out some of the caveats inherent in theirapproach and by suggesting areas in science education of interest to science and technology studies. (shrink)

At the turn of the nineteenth and twentieth centuries a concerted effort was made in the discipline of fluid mechanics to make hidden and fleeting processes visible and to capture the results photographically. I examine two important cases. One concerns the photographs taken by H. S. Hele-Shaw in the 1890s showing the flow of a “perfect”, frictionless fluid. The other case deals with the photographs of boundary layer separation taken by Ludwig Prandtl. These were presented to the Third International Congress (...) of Mathematicians in Heidelberg in 1904. My concern in both cases will be with the relation of the photographs to the reality actually or putatively portrayed in the photograph. Superficially the two cases are very different. “Perfect” fluids were accepted as mere mathematical abstractions to which nothing real could correspond while the reality of the boundary layer has been accepted as a discovery of enormous physical and technical importance. A detailed examination, however, suggests some inner connections of a kind that challenges the understanding of certain “common sense” distinctions between the two cases.Keywords: Sichtbarmachung; Fluid mechanics; Perfect fluids; Boundary layer; Social construction; Prandtl; Hele-Shaw. (shrink)

To date, little is known about when and to what degree science students begin to participate in authentic scientific graphing practices. This article presents the results of a series of studies on the production, transformation, and interpretation of graphical representation from Grade 8 to professional scientific practice both in formal testing situations and in the course of field/laboratory work. The results of these studies can be grouped into two major areas. First, there is a discontinuity in the graph-related practices that (...) marks a boundary between people who engage in work that requires them to transform data into graphical representations and people who do not have such experiences. Second, the didactic practices of high school textbooks and university lectures exhibit a marked discontinuity relative to graphing practices in scientific journals. Graphs used in didactic circumstances may be associated with students’ difficulties in interpreting “real data.” It appears that school teachers and university professors do little to put their students on trajectories of increasing participation in authentic scientific graphing practices. (shrink)

ABSTRACT In 1956 the biomedical world was surprised to hear a report that human cells each contained forty six chromosomes, rather than the forty eight count that had been documented since the 1920s. Application of available techniques to culture human cells in vitro, halt their division at metaphase, and disperse chromosomes in an optical plane permitted perception of visual images not seen before. Researchers continued to obtain the preconceived forty eight counts until reeducation with these novel epistemic ‘chromosomes’ convinced them (...) that they could confidently report forty six chromosomes per cell. Within only a few years, and virtually without dissent, the social community of human cytogeneticists agreed upon a shared visual culture of human chromosome count and morphology. The initial forty six count proved not to be an anomaly. A new comparison of historical and ethnomethodological studies has suggested a better understanding of how applied technologies coupled with altered human perceptions established a new science. Human cytogenetics then collaborated with medical genetics to correlate changes in the new human karyotype with disorders of clinical significance. (shrink)

Biological sciences have strived to adopt the conceptual framework of physics and have become increasingly quantitatively oriented, aiming to refute the assertion that biology appears unquantifiable, unpredictable, and messy. But despite all effort, biology is characterized by a paucity of quantitative statements with universal applications. Nonetheless, many biological disciplines—most notably molecular biology—have experienced an ascendancy over the last 50 years. The underlying core concepts and ideas permeate and inform many neighboring disciplines. This surprising success is probably not so much attributable (...) to mathematical and statistical approaches in molecular biology, but rather to the preponderance of qualitative approaches, especially visualization. Visualizations can be afforded by quantitative research, but usually they rely on both, quantitative and qualitative research. I claim the following three features to be responsible for the unceasing zeal for using visualizations: visual representations facilitate reasoning, images can be cognitively processed in a “fast” manner, and abstractions of visual representations prompt conceptual advances. In summary, visualizations have largely contributed to the success of molecular biology by conveying its concepts to other disciplines, and at the same time, eclipsing mere quantitative approaches. However, visualizations also bear the risk of misinterpretation when traversing neighboring disciplines and even more so when pervading nonscientific domains. (shrink)

In 1675, Burchard de Volder became the first university physics professor to introduce the demonstration of experiments into his lectures and to create a special university classroom, The Leiden Physics Theatre, for this specific purpose. This is surprising for two reasons: first, early pre-Newtonian experiment is commonly associated with Italy and England, and second, de Volder is committed to Cartesian philosophy, including the view that knowledge gathered through the senses is subject to doubt, while that deducted from first principles is (...) certain. On the surface, it is curious that such a man would bring experiments to university physics. After all, in demonstrating experiments to his students, he was teaching them through their senses, not reason. However, if we consider the institutional context of de Volder’s teaching, we come to see de Volder’s Cartesian experimentalism as representative of a certain form of pre-Newtonian Dutch Cartesian science, as well as part of a larger tradition of teaching through observation at the University of Leiden. Considering de Volder’s institutional context will help us see that de Volder’s experimentalism was not in spite of his Cartesianism, but motivated by it. This paper will describe de Volder’s physics curriculum, the Theatre in which it was taught and how his work predates similar efforts in other European Universities. The second part will consider three aspects of the culture at the University of Leiden: a tradition of teaching through observation, a particular reception of Cartesianism, and an eclectic approach to the New Philosophy. The concluding portion shows how de Volder would have understood his enterprise in Cartesian terms. (shrink)