Theory of illness causation is an important issue in all biomedical sciences, and solid etiological explanations are needed in order to develop therapeutic approaches in medicine and preventive interventions in public health. Until now, the literature about the theoretical underpinnings of illness causation research has been scarce and fragmented, and lacking a convenient summary. This interdisciplinary book provides a convenient and accessible distillation of the current status of research into this developing field, and adds a personal flavor to the discussion (...) by proposing the etiological stance as a comprehensive approach to identify modifiable causes of illness. (shrink)

“Perception is controlled hallucination,” according to proponents of predictive processing accounts of vision. I say they are right that something like this is a consequence of their view but wrong in how they have pursued the idea. The focus of my counterproposal is the causal theory of perception, which I develop in terms of a productive concept of causation. Cases of what otherwise seem like successful perception are instead mere veridical hallucination if predictive processing accounts are correct, I argue, because (...) of the role played within such accounts by absences, which cannot enter into productive causal relations. -/- I offer two arguments in support of the productive theory of perception. The first is loosely Kantian, focusing on the role that receptivity and spontaneity play in perception. The second focuses on what perception and hallucination have in common. I conclude with a series of objections and replies. (shrink)

ABSTRACTAccording to many naturalists, our ordinary conception of the world is in tension with the scientific image: the conception of the world provided by the natural sciences. But in this paper, I present a critique of naturalism with precedents in the post-Kantian idealist tradition. I argue that, when we consider our actual linguistic behavior, there is no evidence that the truth of our ordinary judgments hinges on what the scientific image turns out to be like. I then argue that the (...) best explanation of this result is that the norms and presuppositions operating in ordinary discourse are different from the norms and presuppositions operating in scientific discourse. So naturalistic attempts to undermine the manifest image are illegitimate attempts to critique a practice ‘from the outside’. (shrink)

I argue that the best interpretation of the general theory of relativity has need of a causal entity, and causal structure that is not reducible to light cone structure. I suggest that this causal interpretation of GTR helps defeat a key premise in one of the most popular arguments for causal reductionism, viz., the argument from physics.

I argue that transference is, ultimately, identity over time, and that identity over time can't possibly be causation. Transference, then, fails as an analysis of causation.

The transference theory reduces causation to the transmission of physical conserved quantities, like energy or momenta. Although this theory aims at applying to all felds of physics, we claim that it fails to account for a quantum electrodynamic effect, viz. the Aharonov-Bohm effect. After having argued that the Aharonov-Bohm effect is a genuine counter-example for the transference theory, we offer a new physicalist approach of causation, ontic and modal, in which this effect is embedded.

Obgleich die Ausdrücke ‚moralische Pflicht’ und ‚moralische Verantwortung’ auf den ersten Blick nahezu austauschbar scheinen, ist in einigen Debatten dennoch fast ausschließlich von moralischer Verantwortung die Rede. Dies gilt insbesondere für die moralische Beurteilung von individuellen Handlungen in kollektiven Kontexten. Hier scheint die Rede von einer ‚kollektiven Verantwortung‘ besonders attraktiv zu sein. In diesem Aufsatz setze ich mich diesem Trend entgegen und argumentiere dafür, dem Pflichtbegriff in kollektiven Kontexten gegenüber dem Begriff der Verantwortung den Vorrang zu geben. Mein Fokus liegt (...) hierbei auf einer bestimmten Art von Handlungen in kollektiven Kontexten, nämlich auf Handlungen in sogenannten Aggregatkollektiven. Von Aggregatkollektiven verursachte Schäden sind häufig kumulative Schäden, bei denen die Handlungen der Mitglieder eines Aggregatkollektivs einzeln betrachtet keinen merklichen Unterschied für das Auftreten des Schadens machen. Die Rede von Verantwortung legt ein Haftbarkeitsmodell moralischer Verantwortung nahe, welches sich in Bezug auf Handlungen in Aggregatkollektiven als problematisch erweist. Ich zeige, dass Kants Konzeption unvollkommener Pflichten eine vielversprechende Alternative zu dem kausal gefärbten Begriff der moralischen Verantwortung darstellt. Durch den Spielraum, den unvollkommene Pflichten Akteuren lassen, bieten sie eine ähnliche Offenheit wie der Begriff der moralischen Verantwortung. Anders als die Zuschreibung von Verantwortung vermeidet die Rede von unvollkommenen Pflichten jedoch die in kollektiven Kontexten oft inadäquate und kontraproduktive Assoziation von Haftung und Schuld. (shrink)

In this thesis, I give a metascientific account of causality in medicine. I begin with two historical cases of causal discovery. These are the discovery of the causation of Burkitt’s lymphoma by the Epstein-Barr virus, and of the various viral causes suggested for cervical cancer. These historical cases then support a philosophical discussion of causality in medicine. This begins with an introduction to the Russo- Williamson thesis (RWT), and discussion of a range of counter-arguments against it. Despite these, I argue (...) that the RWT is historically workable, given a small number of modifications. I then expand Russo and Williamson’s account. I first develop their suggestion that causal relationships in medicine require some kind of evidence of mechanism. I begin with a number of accounts of mechanisms and produce a range of consensus features of them. I then develop this consensus position by reference to the two historical case studies with an eye to their operational competence. In particular, I suggest that it is mechanistic models and their representations which we are concerned with in medicine, rather than the mechanism as it exists in the world. -/- I then employ these mechanistic models to give an account of the sorts of evidence used in formulating and evaluating causal claims. Again, I use the two human viral oncogenesis cases to give this account. I characterise and distinguish evidence of mechanism from evidence of difference-making, and relate this to mechanistic models. I then suggest the relationship between types of evidence presents us with a means of tackling the reference-class problem. This sets the scene for the final chapter. Here, I suggest the manner in which these two different classes of evidence become integrated is also reflected in the way that developing research programmes change as their associated causal claims develop. (shrink)

Sydney Shoemaker's "Subset Account" offers a new take on determinable properties and the realization relation as well as a defense of non-reductive physicalism from the problem of mental causation. At the heart of this account are the claims that (1) mental properties are determinable properties and (2) the causal powers that individuate a determinable property are a proper subset of the causal powers that individuate the determinates of that property. The second claim, however, has led to the accusation that the (...) effects caused by the instantiation of a determinable property will also be caused by the instantiation of the determinates of that property—so instead of solving the problem of mental causation, the Subset Account ends up guaranteeing that the effects of mental properties (and all other types of determinable property) will be causally overdetermined! In this paper, I explore this objection. I argue that both sides in this debate have failed to engage the question at the heart of the objection: Given that both a determinable property and its determinates have the power to cause some effect (E), does it follow that both will actually cause E when the relevant conditions obtain? To make genuine progress towards answering this question, we need to take a serious look at the metaphysics of causation. With the debate properly reframed and issues about the metaphysics of causation front and center, I explore the question of whether the Subset Account is doomed to result in problematic causal overdetermination. (shrink)

Negative causation occurs when an absence serves as cause, effect, or causal intermediary. Negative causation is genuine causation, or so I shall argue. It involves no physical connection between cause and effect. Thus causes need not be physically connected to their effects.

Questions about the metaphysics of causation may be usefully divided as follows. First, there are questions about the nature of the causal relata, including (1.1) whether they are in spacetime immanence), (1.2) how fine grained they are individuation), and (1.3) how many there are adicity). Second, there are questions about the metaphysics of the causal relation, including (2.1) what is the difference between causally related and causally unrelated sequences connection), (2.2) what is the difference between sequences related as cause to (...) effect, and those related as effect to cause or as joint effects of a common cause direction), and (2.3) what is the difference between sequences involving the cause, and those involving mere conditions selection). (shrink)

In this article, we explore the heuristic power of the theoretical distinction between framework and interaction theories applied to the case of General Relativity. According to the distinction, theories and theoretical elements can be classified into two different groups, each with clear ontological, epistemic and functional content. Being so, to identify the group to which a theory belongs would suffice to know a priori its prospects and limitations in these areas without going into a detailed technical analysis. We make the (...) exercise here with General Relativity, anticipate its ontological, epistemic and functional content and show afterwords that such expectations are justified in this case, being consistent with formal issues of General Relativity. With this, we attempt to make a case for the use of the distinction as a powerful tool for scientific and philosophical analysis. (shrink)

Consider the following claims: -/- 1. The drought caused the famine. -/- 2. Drowsy driving causes crashes. -/- 3. How much I water my plant influences how tall it grows. -/- 4. How much novocaine a patient receives affects how much pain they will feel during dental surgery. -/- The metaphysics of causation asks questions about what it takes for claims like these to be true—what kind of relation the claims are about, and in virtue of what these relations obtain.

The basic kinds of physical causality that are foundational for other kinds of causality involve objects and the causal relations between them. These interactions do not involve events. If events were ontologically significant entities for causality in general, then they would play a role in simple mechanical interactions. But arguments about simple collisions looked at from different frames of reference show that events cannot play a role in simple mechanical interactions, and neither can the entirely hypothetical causal relations between events. (...) These arguments show that physics, which should be authoritative when it comes to the metaphysics of causality, gives no reasons to believe that events are causal agents. Force relations and some cases of energy-momentum transfer are examples of causal relations, with forces being paradigmatic in the macroscopic world, though it is conceivable that there are other kinds of causal relation. A relation between two objects is a causal relation if and only if when it is instantiated by the two objects there is a possibility that the objects that are the terms of the relation could change. The basic metaphysics of causality is about objects, causal relations, changes in objects, and a causal primitive. The paper also includes a discussion of the metaphysics of forces and a discussion of the metaphysics of energy and momentum exchanges. (shrink)

Loewer (in: Physicalism and its discontents, 2001; Philos Phenomenol Res 65:655–663, 2002; in: Contemporary debates in philosophy of mind, 2007) has argued that the nonreductive physicalist should respond to the exclusion problem by endorsing the overdetermination entailed by their view. Kim’s (Physicalism, or something near enough, 2005; in: Contemporary debates in the philosophy of mind, 2007) argument against this reply is based on the premise that mental causation must be a productive relation in order to sustain human agency. In this (...) paper, I challenge the premise that mental causation is a productive relation by appealing to the underlying double prevention structure of the physiological mechanisms of human action. Since the causal pathways from an agent’s mental events to bodily movement involves an absence, mental causation is not productive. This places Kim in a troublesome dilemma in his debate with Loewer: either surrender mental causation or deny that causation is a productive relation. With the support offered for productive mental causation undermined, responses to the exclusion problem based on accepting overdetermination remain viable options for the nonreductive physicalist. (shrink)

Causation is analysed in terms of transference of amounts of conserved quantities between events. Such amounts are tropes. However, causal explanations are directly made true, not by transmission relations but by relations of causal responsibility, of a fact Fc about the cause event c for a fact Ge about the effect event e. Causal responsibility is analysed in terms of causation between events c and e and a law of nature holding between the properties F and G. This account overcomes (...) many objections against other process theories, as well as against accounts in terms of counterfactual dependency and conditional probabilities. (shrink)

The physical and/or intrinsic connection approach to causation has become prominent in the recent literature, with Salmon, Dowe, Menzies, and Armstrong among its leading proponents. I show that there is a type of causation, causation by disconnection, with no physical or intrinsic connection between cause and effect. Only Hume-style conditions approaches and hybrid conditions-connections approaches appear to be able to handle causation by disconnection. Some Hume-style, extrinsic, absence-relating, necessary and/or sufficient condition component of the causal relation proves to be needed.

There are philosophers who deny that causal relations actually exist in nature, arguing that they are merely a product of our perspective as beings capable of intentional actions. In this paper I briefly explain this thesis and consider that it needs to be complemented with a basic non-causal ontological perspective which can account for phenomena taken as causal; I then describe what seems to be a good candidate for such an ontology and finally conclude, however, that it cannot dispense with (...) the concept of causation and that therefore is not the kind of ontology that anti-realism about causal relations requires. (shrink)

This paper examines Wesley Salmon's "process" theory of causality, arguing in particular that there are four areas of inadequacy. These are that the theory is circular, that it is too vague at a crucial point, that statistical forks do not serve their intended purpose, and that Salmon has not adequately demonstrated that the theory avoids Hume's strictures about "hidden powers". A new theory is suggested, based on "conserved quantities", which fulfills Salmon's broad objectives, and which avoids the problems discussed.

I characterize a notion of causal agency that is the causitive component of many transitive verbs. The agency of what I call substantial causes relates objects physically to systems with which they interact. Such agent causation does not reduce to conditionship relations, nor does it cease to play a role in scientific discourse. I argue, contrary to regularity theories, that causal claims do not in general depend for their sense on generalities nor do they entail the existence of laws. Clarification (...) of the relationships among substantial causes, causal processes, and explanatory conditions separates the analysis of causal connection from that of nomological connection. This clarification is then applied to a variety of issues in the analysis of causality. (shrink)

The conservation of energy law, a law of physics that states that the total energy of any closed system is always conserved, is a bedrock principle that has achieved both broad theoretical and experimental support. Yet if interactive dualism is correct, it is thought that the mind can affect physical objects in violation of the conservation of energy. Thus, some claim, the conservation of energy grounds an argument for physicalism. Although critics of the argument focus on the implausibility of causation (...) requiring the transference of energy, I argue that even if causation requires the transference of energy, once we accept the other required premises of the argument that lie behind any supposed argument from the conservation of energy the law of the conservation of energy is revealed as irrelevant to the question of whether the mental is physical. (shrink)

In this paper, I have two primary goals. First, I show that the causal-based story approach in A hybrid formal theory of arguments, stories and criminal evidence is ill suited to negative causation. In the literature, the causal-based approach requires that hypothetical stories be causally linked to the explanandum. Many take these links to denote physical or psychological causation, or temporal precedence. However, understanding causality in those terms, as I will show, cannot capture cases of negative causation, which are of (...) interest to the Law. In keeping with this, I also discuss some of the difficulties Hybrid Theory invites by remaining silent on the nature of the causal links. In my second aim, I sketch a way for Hybrid Theory to overcome this problem. By replacing the original, underlying causal structure with contrastive causation in the law, Hybrid Theory can represent reasoning in which the evidence that is appealed to is causally linked via negative causation to the explananda. (shrink)

And this paper is an attempt to say precisely how, thus addressing a philosophical problem which is commonly taken to be a serious one. It does so, however, in quite an idiosyncratic way. It is based on the account of inductive schemes I have given in (1988) and (1990a) and on the conception of causation I have presented in (1980), (1983), and (1990b), and it intends to fill one of many gaps which have been left by these papers. Still, I (...) have tried to make this paper self-contained. Section 1 explains the philosophical question this paper is about; in more general terms it asks what might be meant by objectifying epistemic states or features of them and to which extent epistemic states can be objectified. The next sections introduce the basis I rely on with formal precision and some explanation; section 2 deals with induction and section 3 with causation. Within these confines, section 4 attempts to give an explication of the relevant sense of objectification and section 5 investigates the extent to which various features of epistemic states are objectifiable. The two most salient results are roughly that the relation "A is a reason for B" cannot be objectified at all and that the relation "A is a cause of B" can be objectified only under substantial, though reasonable restrictions. What has all of this to do with probability? A lot. The paper trades on a pervasive duality between probabilistic and deterministic epistemology, between a probabilistic representation of epistemic states together with a theory of probabilistic causation and another representation of epistemic states which I call deterministic because it lends itself, in a perfectly parallel fashion, to a theory of deterministic causation. Here I explicitly deal only with the deterministic side, but the duality should pave the way for further conclusions concerning objective probabilities and statistical laws. This outlook is briefly expanded in the final section 6. (shrink)

Showcasing original arguments for well-defined positions, as well as clear and concise statements of sophisticated philosophical views, this volume is an ...

It is widely thought that there is an important argument to be made that starts with premises taken from the science of physics and ends with the conclusion of physicalism. The standard view is that this argument takes the form of a causal argument for physicalism. Roughly, physics tells us that the physical realm is causally complete, and so minds (among other entities) must be physical if they are to interact with the world as we think they do. In what (...) follows, I raise problems for this view. After an initial review of the causal argument, I begin my case by showing that the totality of physical truths do not deductively entail the causal completeness of the physical realm, using a double-prevention scenario and causation by omission to show that nonphysical causes of physical effects would not need to violate physical conservation laws. I then move on to raise problems for an inductive argument for causal completeness by drawing on the neo-Russellian view that there is no causation in fundamental physics, and so causation must itself be a realized or derived entity. I conclude by suggesting that the underlying problem is that the causal argument has fallen out of touch with the sophisticated understanding that philosophers have developed of the role of causation within physics. (shrink)

The conservation laws do not establish the central premise within the argument from causal overdetermination – the causal completeness of the physical domain. Contrary to David Papineau, this is true even if there is no non-physical energy. The combination of the conservation laws with the claim that there is no non-physical energy would establish the causal completeness principle only if, at the very least, two further causal claims were accepted. First, the claim that the only way that something non-physical could (...) affect a physical system is by affecting the amount of energy or momentum within it, or redistributing the energy and momentum within it. Second, the claim that redistribution of energy and momentum cannot be brought about without supplying energy or momentum. Both of these claims, however, are exceedingly difficult to defend in the context of the argument. (shrink)

There are three main kinds of causal connections between two events: the transfer of energy, the transfer of information and the triggering of the transfer of one of them or both. There are also other kinds of causal connections.

Process theories of causality seek to explicate causality as a property of individual causal processes. This paper examines the capacity of such theories to account for the asymmetry of causation. Three types of theories of asymmetry are discussed; the subjective, the temporal, and the physical, the third of these being the preferred approach. Asymmetric features of the world, namely the entropic and Kaon arrows, are considered as possible sources of causal asymmetry and a physical theory of asymmetry is subsequently developed (...) with special reference to the questions of objectivity and backwards causation. (shrink)

We use our knowledge of causal relationships to imagine possible events. We also use these relationships to look deep into the past and infer events that were not witnessed or to infer what can not be directly seen in the present. Knowledge of causal relationships allows us to go beyond the here and now. This chapter introduces a new theoretical framework for how this very basic concept might be mentally represented. It proposes an epistemological theory of causation — that is, (...) a theory that specifies the nature of people's knowledge of causation, the notion of causation used in everyday language and reasoning. (shrink)

Two proposals for a physicalistic analysis of causation — the so-called transference model and an account given by J. L. Mackie — are examined and found wanting on the score of physical objectivity. This shortcoming can be remedied, but it is further argued that both proposals embody a too restricted conception of what a physicalistic analysis of causation should be. A more general program is proposed.

This paper offers a defense of backwards in time causation models in quantum mechanics. Particular attention is given to Cramer's transactional account, which is shown to have the threefold virtue of solving the Bell problem, explaining the complex conjugate aspect of the quantum mechanical formalism, and explaining various quantum mysteries such as Schrödinger's cat. The question is therefore asked, why has this model not received more attention from physicists and philosophers? One objection given by physicists in assessing Cramer's theory was (...) that it is not testable. This paper seeks to answer this concern by utilizing an argument that backwards causation models entail a fork theory of causal direction. From the backwards causation model together with the fork theory one can deduce empirical predictions. Finally, the objection that this strategy is questionable because of its appeal to philosophy is deflected. (shrink)

This paper examines the Transference Theory of causation, developed originally by Aronson (1971) and Fair (1979). Three difficulties for that theory are presented: firstly, problems associated with the direction of transference and causal asymmetry; secondly, the case of persistence as causation, for example where a body's own inertia is the cause of its motion; and thirdly the problematic notion of identity through time of physical quantities such as energy or momentum. Finally, the theory is compared with the Conserved Quantity Theory (...) (Dowe 1992c), and it is shown that that account embodies the modifications that the transference theory needs to adopt. (shrink)

In this paper I put forward a suggestion for identifying causality in micro-systems with the specific quantum field theoretic interactions that occur in such systems. I first argue — along the lines of general transference theories — that such a physicalistic account is essential to an understanding of causation; I then proceed to sketch the concept of interaction as it occurs in quantum field theory and I do so from both a formal and an informal point of view. Finally, I (...) present reasons for thinking that only a quantum field theoretic account can do the job — in particular I rely on a theorem by D. Currie and to the effect that interaction cannot be described in (a Hamiltonian formulation of) Classical Mechanics. Throughout the paper I attempt to suggest that the widespread scepticism about the ability of quantum theory to support a theory of causality is mistaken and rests on several misunderstandings. (shrink)

The paper takes a detailed look at a surprising new aspect of the dynamics of rigid bodies. Far from the usual consideration of rigid body theory as a merely technical chapter of classical physics, I demonstrate here that there are solutions to the conservation equations of mechanics that imply the spontaneous, unpredictable splitting of a rigid body in free rotation, something that has direct implications for the problem of causality. The paper also shows that the instability revealed in indeterminist splitting (...) processes does not depend solely on the bodies’ inertial properties but also on the number of dimensions of the physical space they inhabit. The paper concludes with a conjecture on the behavior of rigid bodies in four-dimensional space. (shrink)

The principle that causes always render their effects more likely is fundamental to the enterprise of reducing facts of causation to facts about (objective) chances. This reductionist enterprise faces famous difficulties in accommodating common-sense intuitions about causal processes, if it insists on cashing out causal processes in terms of streams of events in which every event that belongs to the stream is a cause of the adjoining event downstream of it. I shall propose modifications to this way of cashing out (...) causal processes, still well within the reductionist faith. These modifications will allow the reductionist to handle processes successfully, on the assumption that the reductionist proposal is itself otherwise satisfactory. I shall then argue that the reductionist enterprise lies squarely behind the Theory of Relativity, and so has all the confirmatory weight of Relativity behind it. However this is not all good news for reductionists. For throughout I shall simply assume that the reductionist proposal, to the effect that causes are just chance-raisers, is correct. And I shall sidestep problems with that proposal as such. And so I shall show that, if in the end we find the reductionist proposal unsatisfactory, it cannot be on grounds of its treatment of causal processes as such. Thus, while I shall argue that causal processes pose no extra trouble for reductionists, I shall be making a case that all the action between reductionists and their opponents should be focused upon the proposal to reduce the two-term causal relation itself to relations amongst probabilities. (shrink)

Many mathematicians are platonists: they believe that the axioms of mathematics are true because they express the structure of a nonspatiotemporal, mind independent, realm. But platonism is plagued by a philosophical worry: it is unclear how we could have knowledge of an abstract, realm, unclear how nonspatiotemporal objects could causally affect our spatiotemporal cognitive faculties. Here I aim to make room in our metaphysical picture of the world for the causal relevance of abstracta.

I argue that there are some causal relata for which it is indeterminate whether one caused the other. Positing indeterminacy in causation helps us defend contested principles in the logic of causation and makes possible new ways of thinking about the theoretical impact of symmetric causal overdetermination. I close by discussing amendments of current theories of causation that would help explain causal indeterminacy.

I argue that there are some causal relata for which it is indeterminate whether one caused the other. Positing indeterminacy in causation helps us defend contested principles in the logic of causation and makes possible new ways of thinking about the theoretical impact of symmetric causal overdetermination. I close by discussing amendments of current theories of causation that would help explain causal indeterminacy.