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  1. Agential Teleosemantics.Tiago Rama - 2022 - Dissertation, Autonomous University of Barcelona
    The field of the philosophy of biology is flourishing in its aim to evaluate and rethink the view inherited from the previous century ---the Modern Synthesis. Different research areas and theories have come to the fore in the last decades in order to account for different biological phenomena that, in the first instance, fall beyond the explanatory scope of the Modern Synthesis. This thesis is anchored and motivated by this revolt in the philosophy of biology. -/- The central target in (...)
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  • Chances and Propensities in Evo-Devo.Laura Nuño de la Rosa & Cristina Villegas - 2022 - British Journal for the Philosophy of Science 73 (2):509-533.
    While the notion of chance has been central in discussions over the probabilistic nature of natural selection and genetic drift, its role in the production of variants on which populational sampling takes place has received much less philosophical attention. This article discusses the concept of chance in evolution in the light of contemporary work in evo-devo. We distinguish different levels at which randomness and chance can be defined in this context, and argue that recent research on variability and evolvability demands (...)
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  • The Creativity of Natural Selection? Part II: The Synthesis and Since.John Beatty - 2019 - Journal of the History of Biology 52 (4):705-731.
    This is the second of a two-part essay on the history of debates concerning the creativity of natural selection, from Darwin through the evolutionary synthesis and up to the present. In the first part, I focussed on the mid-late nineteenth century to the early twentieth, with special emphasis on early Darwinism and its critics, the self-styled “mutationists.” The second part focuses on the evolutionary synthesis and some of its critics, especially the “neutralists” and “neo-mutationists.” Like Stephen Gould, I consider the (...)
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  • Mutationism, not Lamarckism, captures the novelty of CRISPR–Cas.Jeremy G. Wideman, S. Andrew Inkpen, W. Ford Doolittle & Rosemary J. Redfield - 2019 - Biology and Philosophy 34 (1):12.
    Koonin, in an article in this issue, claims that CRISPR–Cas systems are mechanisms for the inheritance of acquired adaptive characteristics, and that the operation of such systems comprises a “Lamarckian mode of evolution.” We argue that viewing the CRISPR–Cas mechanism as facilitating a form of “directed mutation” more accurately represents how the system behaves and the history of neoDarwinian thinking, and is to be preferred.
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  • CRISPR-Cas immunity: beyond nonself and defence.Thomas Pradeu & Jean-François Moreau - 2019 - Biology and Philosophy 34 (1):6.
    In this commentary of Koonin’s target paper, we defend an extended view of CRISPR-Cas immunity by arguing that CRISPR-Cas includes, but cannot be reduced to, defence against nonself. CRISPR-Cas systems can target endogenous elements and tolerate exogenous elements. We conclude that the vocabulary of “defence” and “nonself” might be misleading when describing CRISPR-Cas systems.
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  • Evolution by Meaning Attribution: Notes on Biosemiotic Interpretations of Extended Evolutionary Synthesis.Jana Švorcová & Karel Kleisner - 2018 - Biosemiotics 11 (2):231-244.
    The aim of this contribution is to investigate certain selected parts of the extended evolutionary synthesis which all have a common denominator, namely evolution by meaning attribution. We start by arguing that living organisms can manipulate and interpret their genetic script via epigenetic modifications in a semiotic manner, that is, by meaning attribution. Genes do not build living beings to be transmitted to future generations. Genes have been shaped by evolution as a memory medium that is transmitted from one generation (...)
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  • Developmental biology, natural selection, and the conceptual boundaries of the modern evolutionary synthesis.David J. Depew & Bruce H. Weber - 2017 - Zygon 52 (2):468-490.
    Using the evolution of the stickleback family of subarctic fish as a touchstone, we explore the effect of new discoveries about regulatory genetics, developmental plasticity, and epigenetic inheritance on the conceptual foundations of the Modern Evolutionary Synthesis. Identifying the creativity of natural selection as the hallmark of the Modern Synthesis, we show that since its inception its adherents have pursued a variety of research projects that at first seemed to conflict with its principles, but were accommodated. We situate challenges coming (...)
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  • Natural selection.Robert Brandon - 2008 - Stanford Encyclopedia of Philosophy.
    Darwin's theory of evolution by natural selection provided the first, and only, causal-mechanistic account of the existence of adaptations in nature. As such, it provided the first, and only, scientific alternative to the “argument from design”. That alone would account for its philosophical significance. But the theory also raises other philosophical questions not encountered in the study of the theories of physics. Unfortunately the concept of natural selection is intimately intertwined with the other basic concepts of evolutionary theory—such as the (...)
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  • Philosophy of CRISPR-Cas: Introduction to Eugene Koonin’s target paper and commentaries.Thomas Pradeu - 2019 - Biology and Philosophy 34 (1):16.
    In this commentary of Koonin’s target paper, we defend an extended view of CRISPR-Cas immunity by arguing that CRISPR-Cas includes, but cannot be reduced to, defence against nonself. CRISPR-Cas systems can target endogenous elements and tolerate exogenous elements. We conclude that the vocabulary of “defence” and “nonself” might be misleading when describing CRISPR-Cas systems.
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  • Biosemiotics and Applied Evolutionary Epistemology: A Comparison.Nathalie Gontier & M. Facoetti - 2021 - In Nathalie Gontier & M. Facoetti (eds.), In: Pagni E., Theisen Simanke R. (eds) Biosemiotics and Evolution. Interdisciplinary Evolution Research, vol 6. Springer, Cham. Cham: pp. 175-199.
    Both biosemiotics and evolutionary epistemology are concerned with how knowledge evolves. (Applied) Evolutionary Epistemology thereby focuses on identifying the units, levels, and mechanisms or processes that underlie the evolutionary development of knowing and knowledge, while biosemiotics places emphasis on the study of how signs underlie the development of meaning. We compare the two schools of thought and analyze how in delineating their research program, biosemiotics runs into several problems that are overcome by evolutionary epistemologists. For one, by emphasizing signs, biosemiotics (...)
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  • Eclipsing the Eclipse?: A Neo-Darwinian Historiography Revisited.Max Meulendijks - 2021 - Journal of the History of Biology 54 (3):403-443.
    Julian Huxley’s eclipse of Darwinism narrative has cast a long shadow over the historiography of evolutionary theory around the turn of the nineteenth century. It has done so by limiting who could be thought of as Darwinian. Peter Bowler used the eclipse to draw attention to previously understudied alternatives to Darwinism, but maintained the same flaw. In his research on the Non-Darwinian Revolution, he extended this problematic element even further back in time. This paper explores how late nineteenth-century neo-Darwinian conceptualizations (...)
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  • Population and organismal perspectives on trait origins.Brian McLoone - 2020 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 83:101288.
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  • Heritable changeability: Epimutation and the legacy of negative definition in epigenetic concepts.Anne Le Goff, Patrick Allard & Hannah Landecker - 2021 - Studies in History and Philosophy of Science Part A 86:35-46.
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  • The struggle for life and adaptation by natural selection.Adam Krashniak - 2021 - Biology and Philosophy 36 (3):1-16.
    While the struggle for life played an important role in the process of natural selection as it was conceived by Darwin, natural selection is commonly characterized today as a process which does not necessarily involve struggle. Nevertheless, there have been some attempts to show the importance of struggle to the process of natural selection. The present paper aims to continue these attempts and clarify the precise evolutionary role of struggle. The paper focuses on a recent dispute regarding the role of (...)
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  • The Multifaceted Legacy of the Human Genome Program for Evolutionary Biology: An Epistemological Perspective.Philippe Huneman - 2019 - Perspectives on Science 27 (1):117-152.
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  • Special Issue Editor’s Introduction: “Revisiting the Modern Synthesis”.Philippe Huneman - 2019 - Journal of the History of Biology 52 (4):509-518.
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