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  1. Queering the genome: ethical challenges of epigenome editing in same-sex reproduction.Adrian Villalba - forthcoming - Journal of Medical Ethics.
    In this article, I explore the ethical dimensions of same-sex reproduction achieved through epigenome editing—an innovative and transformative technique. For the first time, I analyse the potential normativity of this disruptive approach for reproductive purposes, focusing on its implications for lesbian couples seeking genetically related offspring. Epigenome editing offers a compelling solution to the complex ethical challenges posed by traditional gene editing, as it sidesteps genome modifications and potential long-term genetic consequences. The focus of this article is to systematically analyse (...)
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  • Double trouble: Should double embryo transfer be banned?Dominic Wilkinson, G. Owen Schaefer, Kelton Tremellen & Julian Savulescu - 2015 - Theoretical Medicine and Bioethics 36 (2):121-139.
    What role should legislation or policy play in avoiding the complications of in-vitro fertilization? In this article, we focus on single versus double embryo transfer, and assess three arguments in favour of mandatory single embryo transfer: risks to the mother, risks to resultant children, and costs to society. We highlight significant ethical concerns about each of these. Reproductive autonomy and non-paternalism are strong enough to outweigh the health concerns for the woman. Complications due to non-identity cast doubt on the extent (...)
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  • Failures of Imagination: Disability and the Ethics of Selective Reproduction.Marta Soniewicka - 2015 - Bioethics 29 (8):557-563.
    The article addresses the problem of disability in the context of reproductive decisions based on genetic information. It poses the question of whether selective procreation should be considered as a moral obligation of prospective parents. To answer this question, a number of different ethical approaches to the problem are presented and critically analysed: the utilitarian; Julian Savulescu's principle of procreative beneficence; the rights-based. The main thesis of the article is that these approaches fail to provide any appealing principles on which (...)
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  • A critical view on using “life not worth living” in the bioethics of assisted reproduction.Agnes Elisabeth Kandlbinder - forthcoming - Medicine, Health Care and Philosophy:1-15.
    This paper critically engages with how life not worth living (LNWL) and cognate concepts are used in the field of beginning-of-life bioethics as the basis of arguments for morally requiring the application of preimplantation genetic diagnosis (PGD) and/or germline genome editing (GGE). It is argued that an objective conceptualization of LNWL is largely too unreliable in beginning-of-life cases for deriving decisive normative reasons that would constitute a moral duty on the part of intending parents. Subjective frameworks are found to be (...)
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  • Let Us Assume That Gene Editing is Safe—The Role of Safety Arguments in the Gene Editing Debate.Søren Holm - 2019 - Cambridge Quarterly of Healthcare Ethics 28 (1):100-111.
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  • Don't mind the gap: intuitions, emotions, and reasons in the enhancement debate.Alberto Giubilini - 2015 - Hastings Center Report 45 (5):39-47.
    Reliance on intuitive and emotive responses is widespread across many areas of bioethics, and the current debate on biotechnological human enhancement is particularly interesting in this respect. A strand of “bioconservatives” that has explicitly drawn connections to the modern conservative tradition, dating back to Edmund Burke, appeals explicitly to the alleged wisdom of our intuitions and emotions to ground opposition to some biotechnologies or their uses. So-called bioliberals, those who in principle do not oppose human bioenhancement, tend to rely on (...)
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  • Selektion zum Wohl des zukünftigen Kindes?: Präimplantationsdiagnostik, „prokreatives Wohltun“ und die Verantwortung angehender Eltern.Ruth Denkhaus - 2021 - Ethik in der Medizin 34 (1):27-48.
    Der Beitrag setzt sich kritisch mit dem Prinzip des prokreativen Wohltuns von Julian Savulescu und seinen Implikationen für den Umgang mit der Präimplantationsdiagnostik auseinander. PB fordert angehende Eltern dazu auf, aus mehreren möglichen zukünftigen Kindern dasjenige auszuwählen, dessen Leben voraussichtlich am besten verlaufen wird. Paare mit Kinderwunsch sind danach zumindest unter bestimmten Umständen moralisch verpflichtet, eine PID in Anspruch zu nehmen, um die Weitergabe genetisch bedingter Krankheiten zu verhindern. Die Auswahl von Embryonen im Rahmen einer PID kann jedoch nur dann (...)
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  • „Hauptsache das Kind ist gesund?“ – Ethische und rechtliche Fragen am Lebensanfang.Ruth Denkhaus & Julia Inthorn - 2021 - Ethik in der Medizin 34 (1):1-6.
    Der Beitrag setzt sich kritisch mit dem Prinzip des prokreativen Wohltuns von Julian Savulescu und seinen Implikationen für den Umgang mit der Präimplantationsdiagnostik auseinander. PB fordert angehende Eltern dazu auf, aus mehreren möglichen zukünftigen Kindern dasjenige auszuwählen, dessen Leben voraussichtlich am besten verlaufen wird. Paare mit Kinderwunsch sind danach zumindest unter bestimmten Umständen moralisch verpflichtet, eine PID in Anspruch zu nehmen, um die Weitergabe genetisch bedingter Krankheiten zu verhindern. Die Auswahl von Embryonen im Rahmen einer PID kann jedoch nur dann (...)
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  • Looking into the shadow: The eugenics argument in debates on reproductive technologies and practices.Giulia Cavaliere - 2018 - Monash Bioethics Review 36 (1-4):1-22.
    Eugenics is often referred to in debates on the ethics of reproductive technologies and practices, in relation to the creation of moral boundaries between acceptable and unacceptable technologies, and acceptable and unacceptable uses of these technologies. Historians have argued that twentieth century eugenics cannot be reduced to a uniform set of practices, and that no simple lessons can be drawn from this complex history. Some authors stress the similarities between past eugenics and present reproductive technologies and practices (what I define (...)
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  • Parenthood and Procreation.Tim Bayne & Avery Kolers - forthcoming - Stanford Encyclopedia of Philosophy.
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  • Reproductive autonomy: A case study.David Hall & Anton van Niekerk - 2016 - South African Journal of Bioethics and Law 9 (2):61-61.
    Reproductive autonomy has been challenged by the availability of genetic information, disability and the ethics of selective reproduction. Utilitarian and rights-based approaches, as well as procreative beneficence fail to provide compelling reasons for infringing RA, and may even be likened to dangerous eugenics. Parents are not morally obliged to prevent the birth of a disabled child. Society should rather adopt inclusivity, recognising and providing persons with disabilities opportunities for capability and worthwhile lives.
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