Many empirically minded philosophers have used neuroscientific data to argue against the multiple realization of cognitive functions in existing biological organisms. I argue that neuroscientists themselves have proposed a biologically based concept of multiple realization as an alternative to interpreting empirical findings in terms of one‐to‐one structure‐function mappings. I introduce this concept and its associated research framework and also how some of the main neuroscience‐based arguments against multiple realization go wrong. *Received October 2009; revised December 2009. †To contact the author, (...) please write to: Department of Philosophy, 260 English‐Philosophy Building, University of Iowa, Iowa City, IA 52242; e‐mail: carrie‐[email protected]. (shrink)