The paper argues for a pragmatic account of genetic explanation. This is to say that when a disease or other trait is termed genetic, the reasons for singling out genes as causes over other, also necessary, genetic and nongenetic conditions are not wholly theoretical but include pragmatic dimensions. Whether the explanation is the presence of a trait in an individual or differences in a trait among individuals, genetic explanations are context-dependent in three ways: they are relative to a causal background (...) of genetic and nongenetic factors; they are relative to a population; and they are relative to the present state of knowledge. Criteria like causal priority, nonstandardness, and causal efficacy that purport to distinguish objectively between genetic causes and nongenetic conditions either incorporate pragmatic elements or fail for other reasons. When the pragmatic dimensions of genetic explanations are recognized, we come to understand the current phenomenon of geneticization to be a reflection of increased technological capacities to manipulate genes in the laboratory, and potentially the clinic, rather than theoretical progress in understanding how diseases and other traits arise. This calls into question the value of the search for theoretical definitions of designations like genetic disease or genetic susceptibility as directives for action. (shrink)

Philosophers of science take it as a datum that Mayor John's having syphilis explains why he, rather than certain nonsyphilitics, had paresis. Using a new hypothetical example, the case of the two dams, it is argued that three independent considerations invalidate these philosophers' starting point.

This paper offers a dialogue theory of explanation. A successful explanation is defined as a transfer of understanding in a dialogue system in which a questioner and a respondent take part. The questioner asks a special sort of why-question that asks for understanding of something and the respondent provides a reply that transfers understanding to the questioner. The theory is drawn from recent work on explanation in artificial intelligence (AI), especially in expert systems, but applies to scientific, legal and everyday (...) conversational explanations. (shrink)

In this paper I want to show that a main theme of Neurath’s philosophical work was the formulation of a radically empiricist theory of science. His approach, dubbed "encyclopedism", can be characterized by the following five theses: scientific knowledge is (1) fallible, (2) pluralistic, (3) holistic, (4) can be systematized only locally, and (5) does not give us a faithful description of the real world. (4) is to be considered as the most original thesis of encyclopedism and is discussed in (...) detail. (shrink)

For a number of years now, we, as philosophers of science, have been enjoined by more and more of our colleagues to understand the task of developing a philosophy of science to be itself a scientific task. We are told that if we want to understand science we have no better (and perhaps indeed no other) path to such an understanding than the path of science itself. We should view ourselves as ultimately attempting to arrive at a relatively complete theoretical (...) understanding of how science proceeds. This is a call tonaturalizephilosophy of science.Somewhat more recently some philosophers of science have become impatient even with those who have taken up the naturalist banner. It isn’t enough, they tell us, to arrive at an understanding of the nature of philosophy of science that proclaims it to be one science among many. (shrink)

In classical physics, probabilistic or statistical knowledge has been always related to ignorance or inaccurate subjective knowledge about an actual state of affairs. This idea has been extended to quantum mechanics through a completely incoherent interpretation of the Fermi-Dirac and Bose-Einstein statistics in terms of "strange" quantum particles. This interpretation, naturalized through a widespread "way of speaking" in the physics community, contradicts Born's physical account of Ψ as a "probability wave" which provides statistical information about outcomes that, in fact, cannot (...) be interpreted in terms of 'ignorance about an actual state of affairs'. In the present paper we discuss how the metaphysics of actuality has played an essential role in limiting the possibilities of understating things differently. We propose instead a metaphysical scheme in terms of powers with definite potentia which allows us to consider quantum probability in a new light, namely, as providing objective knowledge about a potential state of affairs. (shrink)

Methodological likelihoodism is the view that it is possible to provide an adequate self-contained methodology for science on the basis of likelihood functions alone. I argue that methodological likelihoodism is false by arguing that an adequate self-contained methodology for science provides good norms of commitment vis-a-vis hypotheses, articulating minimal requirements for a norm of this kind, and proving that no purely likelihood-based norm satisfies those requirements.

The present paper aims to give an account of pessimistic meta-induction and reply to some representative realist authors who want to consider PMI a fallacy. Most of that accounts are misinterpretations of Laudant’s ideas and fails the target. This work intend that PMI is neither a induction nor a reductio, but a skeptic challenge. If this is right then PMI could not be a fallacy and the realism cannot escape from the task of explain why the success is a good (...) indication for the truthlikeness of the current theories. (shrink)

Russell’s claim that only structural knowledge of the world is possible was influentially criticized by Newman as rendering scientific discoveries trivial. I show that a version of this criticism also applies to the “structural realism” more recently advocated by Worrall, which requires continuity of formal structure between predecessor and successor scientific theories. The problem is that structure, in its common set-theoretical construal, is radically underdetermined by the entities and relations over which it is defined, rendering intertheoretic continuity intolerably cheap. I (...) show that this problem may be overcome by supplementing the purely formal relation of intertheoretic isomorphism with the semiformal “Ontological Reductive Links” developed by Moulines and others of the German “structuralist” approach to the philosophy of science. (shrink)

In this article, two issues regarding mechanisms are discussed. The first concerns the relationships between “mechanism description” and “mechanism explanation.” It is proposed that it is rather plausible to think of them as two distinct epistemic acts. The second deals with the different molecular biology explanatory contexts, and it is shown that some of them require physics and its laws.

Abstract Not much scholarly work is needed in order to stumble across many passages where Edmund Husserl seems to advocate an anti-realist attitude towards the natural sciences. This tendency, however, is not well-received within the secondary literature. While some commentators criticize Husserl for his alleged scientific anti-realism, others argue that Husserl's position is much more realist than the first impression indicates. It is against this background that I want to argue for the following theses: a) The basic outlook of Husserl's (...) epistemology as well as his more substantial comments regarding the natural sciences indeed result in a (sophisticated version of) scientific anti-realism which bears certain resemblances to Bas van Fraassen's constructive empiricism; b) This scientific anti-realism can be defended against the two most common objections raised in the secondary literature; c) It is only by means of this sophisticated version of scientific anti-realism that phenomenology can circumvent the problem of ?scientific objectivism? (shrink)

This is a defense of the doctrine of scientific realism. SR is defined through the following two claims: Most essential unobservables posited by the well-established current scientific theories exist independently of our minds. We know our well-established scientific theories to be approximately true. I first offer positive argumentation for SR. I begin with the so-called 'success arguments' for SR: 1) scientific theories most of the times entail successful predictions; 2) science is methodologically successful in generating empirically successful theories. SR explains (...) these facts via inference to the best explanation. I combine Hacking's experimental argument for entity realism with Salmon's common-cause principle. I take entity realism to be foundational to SR: one may believe in the existence of some theoretical entities without believing in any particular theory in which these are embedded. Its motivation comes from experimental practice, where the manipulation of these entities often relies on incompatible theoretical accounts. The underdetermination topic is thereafter discussed. Several attempts to distinguish between an observable and an unobservable realm are critically discussed, as well as the possibility that for any given theory, there are empirically equivalents generated by means of algorithms. I present extensive argumentation to the effect that such algorithmic rivals are not to be taken seriously. Social constructivism is being critically treated. I proceed by distinguishing between a metaphysical, a semantic, and an epistemic variant of SC. I conclude that only a moderate metaphysical constructivism can stand on its own feet. Its claim is merely that some facts about the world are socially constructed. I finish with a plea for a selective SR, able to do justice to the presence of both instrumentalism and modest constructivism in scientific practice. (shrink)

One can (for the most part) formulate a model of a classical system in either the Lagrangian or the Hamiltonian framework. Though it is often thought that those two formulations are equivalent in all important ways, this is not true: the underlying geometrical structures one uses to formulate each theory are not isomorphic. This raises the question whether one of the two is a more natural framework for the representation of classical systems. In the event, the answer is yes: I (...) state and prove two technical results, inspired by simple physical arguments about the generic properties of classical systems, to the effect that, in a precise sense, classical systems evince exactly the geometric structure Lagrangian mechanics provides for the representation of systems, and none that Hamiltonian mechanics does. The argument not only clarifies the conceptual structure of the two systems of mechanics, their relations to each other, and their respective mechanisms for representing physical systems. It also provides a decisive counter-example to the semantical view of physical theories, and one, moreover, that shows its crucial deficiency: a theory must be, or at least be founded on, more than its collection of models (in the sense of Tarski), for a complete semantics requires that one take account of global structures defined by relations among the individual models. The example also shows why naively structural accounts of theory cannot work: simple isomorphism of theoretical and empirical structures is not rich enough a relation to ground a semantics. (shrink)

If mental anomalism is to be interpreted as a thesisunique to psychology, the anomalousness must begrounded in some feature unique to the mental,presumably its rational nature. While the ground forsuch arguments from normativity has been notoriouslyslippery terrain, there are two recently influentialstrategies which make the argument precise. The firstis to deny the possibility of psychophysical bridgelaws because of the different constitutive essences ofmental and physical laws, and the second is to arguethat mental anomalism follows from the uncodifiabilityof rationality. In this (...) paper I argue that bothstrategies fail – the latter because it conflates primafacie and all things considered rationality and theformer because it rests on a false premise, theprinciple of the rational character of belief. Idistinguish four different formulations of thisprinciple and argue that those formulations which areplausible cannot support the argument for mentalanomalism. (shrink)

Martin Kusch has recently defended Bas van Fraassen’s controversial view on microscopes, according to which these devices are not ‘windows on an invisible world’, but rather ‘image generators’. The two authors also claim that, since in a microscopic detection it is not possible to empirically investigate the geometrical relations between all the elements involved, one is entitled to maintain an agnostic stance about the reality of the entity allegedly represented by the produced image. In this paper I argue that, contrary (...) to what Kusch maintains, this might not be a neutral way to render scientific evidence. Moreover, a constructive empiricist can support a realist interpretation of microscopic images. In fact, constructive empiricism and van Fraassen’s own anti-realism do not necessarily amount to the same thing. (shrink)

This paper concerns local yet systematic problems of contrastive underdetermination of model choice in cognitive neuroscience debates about the so-called two visual systems hypothesis. The underdetermination problem is systematically generated by the way certain assumptions about the representationalist nature of computation are translated into experimental practice. The problem is that behavioural data underdetermine the choice between competing representational models. In this paper, I diagnose how these assumptions generate underdetermination problems in the choice between competing functional models of perception–action. Using the (...) tools of philosophy of science, I describe the type of underdetermination and sketch a possible cure. (shrink)

A popular view maintains that supposition is a kind of cognitive mental state, very similar to belief in essential respects. Call this view “cognitivism about supposition”. There are at least three grades of cognitivism, construing supposition as (i) a belief, (ii) belief-like imagination or (iii) a species of belief-like imagination. I shall argue against all three grades of cognitivism and claim that supposition is a sui generis form of imagination essentially dissimilar to belief. Since for good reasons (i) is not (...) supported in the literature, I shall dwell on (ii) and (iii). Without further explanation supposition has been very often merely postulated as being nothing but belief-like imagination—that is, (ii). I shall show that at least two considerations undermine (ii). First, supposition and belief-like imagination are governed by different norms, more precisely the former is freer than the latter and requires minimal or no mental effort. Second, contrary to belief-like imagination, supposition is “cold”, in that it is typically dissociated from emotional reactions. Proponents of (iii) face the pressure of explaining these differences between supposition and belief-like imagination too. I shall argue that they have not sufficiently motivated the claim that supposition is belief-like. In particular they fail to accommodate precisely the dimensions of supposition pertaining to its normativity and emotionality. I shall close with a sketch of a new account of supposition. (shrink)

This paper challenges a central tenet of constructive empiricism, namely that empirical adequacy has a privileged epistemic status. I argue that perceptions of observables are theory-wrought, and theory-wrought in the same ways as the observation sentences we use to describe those perceptions, van Fraassen can draw no privileged or fundamental distinction between what we observe and interpreting those observations through theory. Since empirical adequacy depends upon accurately describing what we observe, and we have no theory-independent reason to believe that what (...) we ‘observe’ is a reflection of what is true, then empirical adequacy can inherit no special connection to what is real via what we observe. The epistemological significance of empirical adequacy is thereby reduced. (shrink)

This dissertation consists of three parts. Part I is a defense of an artificial language methodology in philosophy and a historical and systematic defense of the logical empiricists' application of an artificial language methodology to scientific theories. These defenses provide a justification for the presumptions of a host of criteria of empirical significance, which I analyze, compare, and develop in part II. On the basis of this analysis, in part III I use a variety of criteria to evaluate the scientific (...) status of intelligent design, and further discuss confirmation, reduction, and concept formation. (shrink)

Economics is currently experiencing a climate of uncertainty regarding the soundness of its theoretical framework and even its status as a science. Much of the criticism is within the discipline, and emphasises the alleged failure of the neoclassical viewpoint. This article proposes the deployment of partial modelling, utilising Boolean networks (BNs), as an inductive discovery procedure for the development of economic theory. The method is presented in detail and then linked to the Semantic View of Theories (SVT), closely identified with (...) Bas van Fraassen and Patrick Suppes, in which models are construed as mediators creatively negotiating between theory and reality. It is suggested that this approach may be appropriate for economics and, by implication, for any science in which there is no consensus theory, and a wide range of viewpoints compete for acceptance. (shrink)

The notion of a severe test has played an important methodological role in the history of science. But it has not until recently been analyzed in any detail. We develop a generally Bayesian analysis of the notion, compare it with Deborah Mayo’s error-statistical approach by way of sample diagnostic tests in the medical sciences, and consider various objections to both. At the core of our analysis is a distinction between evidence and confirmation or belief. These notions must be kept separate (...) if mistakes are to be avoided; combined in the right way, they provide an adequate understanding of severity. Those who think that the weight of the evidence always enables you to choose between hypotheses “ignore one of the factors (the prior probability) altogether, and treat the other (the likelihood) as though it ...meant something other than it actually does. This is the same mistake as is made by someone who has scruples about measuring the arms of a balance (having only a tape measure at his disposal ...), but is willing to assert that the heavier load will always tilt the balance (thereby implicitly assuming, although without admitting it, that the arms are of equal length!). (Bruno de Finetti, Theory of Probability)2. (shrink)

In this paper I reconstruct and compare criteria of theoreticity that have been developed by Carnap, Sneed and proponents of the Munich school of structuralist philosophy of science. For this purpose I develop a unified framework in which one can transform model-theoretic theory representations into linguistic ones, and vice versa. This bridges the gap between statement and non-statement view and allows a precise comparison of linguistic and model-theoretic criteria of theoreticity. In the final part I suggest a system of improved (...) definitions of theoreticity and pre-theoreticity. (shrink)

In this paper, I distinguish scientific models in three kinds on the basis of their ontological status—material models, mathematical models and fictional models, and develop and defend an account of fictional models as fictional objects—i.e. abstract objects that stand for possible concrete objects.

Recently some philosophers have urged that connectionist artificial intelligence is (potentially) eliminative for the propositional attitudes of folk psychology. At the same time, however, these philosophers have also insisted that since philosophy of science has failed to provide criteria distinguishing ontologically retentive from eliminative theory changes, the resulting eliminativism is not principled. Application of some resources developed within the semantic view of scientific theories, particularly recent formal work on the theory reduction relation, reveals these philosophers to be wrong in this (...) second contention, yet by and large correct in the first. (shrink)

The problem of unconceived alternatives states that, since scientists have recurrently failed to conceive relevant theoretical alternatives for some domains of science, current scientists are probably also failing to do so. Therefore, there may be theories which still exceed the grasp of scientists’ imagination, and one should not endorse a realist stance towards current science. In this paper, I raise a conceptual worry for the formulation of this problem: what does it mean to say that scientists failed to conceive a (...) relevant theory? What aggravates the problem is that no simple notion of relevance makes the New Induction as strong as it initially seems. I consider the three more obvious interpretations of relevance: relevance as objective probability; relevance as epistemic probability assessed by current scientists; and relevance as epistemic probability assessed by past scientists. I argue that assuming any of these three notions implies difficulties for the New Induction, hence their proponents shouldn’t take the notion of relevance for granted. A more precise definition of relevance is essential to understand what are the difficulties surrounding the problem of unconceived alternatives as an epistemic worry. Until now, such notion is missing. KeyWords: Scientific realism, unconceived alternatives, Kyle Stanford, New Induction, Pessimistic Induction. (shrink)

The thesis focuses on what impact the use of idealizations has on the realism/anti-realism debate concerning the fundamental laws of physics. My aim is modest. It is not to present an argument for either the realist or the anti-realist position but rather to show where the debate stands once we have considered recent arguments by Laymon and Cartwright which have made use of the notion of idealization assumptions. My intent is to point out the difficulties of Laymon's argument for realism (...) in the hope of showing what must be accomplished in providing a more convincing argument for realism. I will also suggest that although Laymon's proposal is problematic, it still poses a serious problem for van Fraassen's form of anti-realism, constructive empiricism. (shrink)

Quantum Mechanics has faced deep controversies and debates since its origin when Werner Heisenberg proposed the first mathematical formalism capable to operationally account for what had been recently discovered as the new field of quantum phenomena. Today, even though we have reached a standardized version of QM which is taught in Universities all around the world, there is still no consensus regarding the conceptual reference of the theory and, if or if not, it can refer to something beyond measurement outcomes. (...) In this work we will argue that the reason behind the impossibility to reach a meaningful answer to this question is strictly related to the 20th Century Bohrian-positivist re-foundation of physics which is responsible for having introduced within the theory of quanta a harmful combination of metaphysical dogmatism and naive empiricism. We will also argue that the possibility of understanding QM is at plain sight, given we return to the original framework of physics in which the meaning of understanding has always been clear. (shrink)

Newman’s objection can be used to argue that structuralism fails to specify a unique structure for the unobservable world, and hence, one can argue, it is ultimately a trivial task to determine the structure that the world ultimately has. Provided there are enough objects, any structure can be made compatible with that structure. We formulate a pragmatically enriched version of structuralism that avoids the Newman objection. For this purpose, we return to Carnap’s conception of founded relations, and provide a different (...) interpretation of them. According to Carnap, these are real, experienceable, physical relations. We argue that, when we specify a structural description of a given physical system, if we rely on such founded relations—provided they are properly understood—the threat of the Newman objection is avoided. However, pure structuralism has to be given up, and a form of empiricism can then be advanced. Finally, by using founded relations, we offer a framework in terms of which different conceptions can be articulated to avoid the Newman problem as well. (shrink)

Duhem used historical arguments to draw philosophical conclusions about the aim and structure of physical theory. He argued against explanatory theories and in favor of theories that provide natural classifications of the phenomena. This paper presents those arguments and, with the benefit of hindsight, uses them as a test case for the prevalent contemporary use of historical arguments to draw philosophical conclusion about science. It argues that Duhem provides us with an illuminating example of philosophy of science developing as a (...) contingent, though natural, response to problems arising in a particular scientific context and under a particular understanding of the history of science in that context. It concludes that the history of science provides little support for interesting theses about the present or future state of science. (shrink)

I investigate what it means to have an interpretation of our language, how we manage to bestow a determinate interpretation to our utterances, and to which extent our interpretation of the world is determinate. All this is done in dialogue with van Fraassen's insightful discussion of Putnam's model-theoretic argument and of scientific structuralism.

In this paper I argue that demonstrative induction can deal with the problem ofthe underdetermination of theory by evidence. I present the historical case studyof spectroscopy in the early 1920s, where the choice among different theorieswas apparently underdetermined by spectroscopic evidence concerning the alkalidoublets and their anomalous Zeeman effect. By casting this historical episodewithin the methodological framework of demonstrative induction, the localunderdetermination among Bohr's, Heisenberg's, and Pauli's rival theories isresolved in favour of Pauli's theory of the electron's spin.

This article concerns the split between syntactic and semantic approaches to scientific theories. It aims at showing that an axiomatic representation of a scientific theory is a precondition of comprehending if the models of contain infinite entities. This result is established on the basis of the proposition that the human mind—which is finitely bounded for all we know—is not capable of directly grasping infinite entities. In view of this cognitive limitation, an indirect and finite representation of possibly infinite components of (...) the models of a scientific theory proves to be indispensable. Sets of axioms and sets of axiom schemes provide such a representation. These considerations will be cast into an argument for an axiomatic conception of scientific theories. The article concludes with a case study of the ideal gas model. (shrink)