This paper examines Duhem’s concept of good sense as an attempt to support a non rule-governed account of rationality in theory choice. Faced with the underdetermination of theory by evidence thesis and the continuity thesis, Duhem tried to account for the ability of scientists to choose theories that continuously grow to a natural classification. I will examine the concept of good sense and the problems that stem from it. I will also present a recent attempt by David Stump to link (...) good sense to virtue epistemology. I will argue that even though this approach can be useful for the better comprehension of the concept of good sense, there are some substantial differences between virtue epistemologists and Duhem. In the light of this reconstruction of good sense, I will propose a possible way to interpret the concept of good sense, which overcomes the noted problems and fits better with Duhem’s views on scientific method and motivation in developing the concept of good sense. (shrink)

Scientists often use aesthetic values in the evaluation and choice of theories. Aesthetic values are not only regarded as leading to practically more useful theories but are often taken to stand in a special epistemic relation to the truth of a theory such that the aesthetic merit of a theory is evidence of its truth. This paper explores what aesthetic considerations influence scientists' reasoning, how such aesthetic values relate to the utility of a scientific theory, and how one can justify (...) the epistemic role for such values. The paper examines ways in which the link between beauty and truth can be defended, the challenges facing such accounts, and explores alternative epistemic roles for aesthetic values in scientific practice. (shrink)

Although there is universal consensus both in the science education literature and in the science standards documents to the effect that students should learn not only the content of science but also its nature, there is little agreement about what that nature is. This led many science educators to adopt what is sometimes called “the consensus view” about the nature of science (NOS), whose goal is to teach students only those characteristics of science on which there is wide consensus. This (...) is an attractive view, but it has some shortcomings and weaknesses. In this article we present and defend an alternative approach based on the notion of family resemblance. We argue that the family resemblance approach is superior to the consensus view in several ways, which we discuss in some detail. (shrink)

According to an influential characterisation of reflective equilibrium, it is a kind of algorithm for licensing explicitly normative claims in philosophical inquiries. Call this the machine-view of reflective equilibrium. The machine-view implies a causal relation between input and output data that is devoid of human agency in any significant sense. In this paper, I argue for a neo-Aristotelian alternative view. According to this view, the judgement that is called forth in the decision procedure of reflective equilibrium is a rational response (...) of an epistemic agent, which integrates the whole of her character as a knower, both cognitive and affective, and which cannot be reduced to the explicit following of rules or an algorithm. Unlike the machine-view, this alternative account is able to support the dynamic structure and the normative status of the decision procedure. (shrink)

This article examines what realists and anti-realist debates are all about. Through presenting the core of the main arguments in these debates, these are significant arguments and they are the kind of arguments that can clarify what it meant by ‘truth’ between Realist and anti-realist in general. The concluding remark is that though the main anti- realist’s arguments in these debates can be seen as some powerful arguments through raising questions on the relationship between theory and evidence, success and truth. (...) However, the success of science and the use of science in everyday life has not been given any satisfactory explanations by the anti-realists nor the use of it has been shut out from the daily life by these arguments against it. (shrink)

A widespread concern within philosophy has been, and continues to be, to determine which domains of discourse address real, robust, not‐merely‐deflationary facts, and which do not. But a threat to the legitimacy of this concern is the extreme lack of consensus amongst philosophers on the question of how to tell whether or not a given domain is oriented towards ‘robust reality’. The present paper criticizes Kit Fine’s attempt to settle that question. This discussion is followed by some considerations suggesting that (...) there is no good answer to it, that the notion of ‘robust reality’ is defective and ought to be abandoned. (shrink)

The point of this paper is to provide a principled framework for a naturalistic, interactivist-constructivist model of rational capacity and a sketch of the model itself, indicating its merits. Being naturalistic, it takes its orientation from scientific understanding. In particular, it adopts the developing interactivist-constructivist understanding of the functional capacities of biological organisms as a useful naturalistic platform for constructing such higher order capacities as reason and cognition. Further, both the framework and model are marked by the finitude and fallibility (...) that science attributes to organisms, with their radical consequences, and also by the individual and collective capacities to improve their performances that learning organisms display. Part A prepares the ground for the exposition through a critique of the dominant Western analytic tradition in rationalising science, followed by a brief exposition of the naturalist framework that will be employed to frame the construction. This results in two sets of guidelines for constructing an alternative. Part B provides the new conception of reason as a rich complex of processes of improvement against epistemic values, and argues its merits. It closes with an account of normativity and our similarly developing rational knowledge of it, including (reflexively) of reason itself. (shrink)

Opposing Quine, I defend the view that some of the statements we accept are immune to empirical revision. My examples include instances of Schema and abbreviative definitions. I argue that it serves important cognitive purposes to hold statements of these kinds immune to revision, and that it is epistemically permissible for us to do so. At the end, I briefly consider the question of whether the rationale for these claims might be extended to show that additional statements are unrevisable.

Two of the most influential theories about scientific inference are inference to the best explanation and Bayesianism. How are they related? Bas van Fraassen has claimed that IBE and Bayesianism are incompatible rival theories, as any probabilistic version of IBE would violate Bayesian conditionalization. In response, several authors have defended the view that IBE is compatible with Bayesian updating. They claim that the explanatory considerations in IBE are taken into account by the Bayesian because the Bayesian either does or should (...) make use of them in assigning probabilities to hypotheses. I argue that van Fraassen has not succeeded in establishing that IBE and Bayesianism are incompatible, but that the existing compatibilist response is also not satisfactory. I suggest that a more promising approach to the problem is to investigate whether explanatory considerations are taken into account by a Bayesian who assigns priors and likelihoods on his or her own terms. In this case, IBE would emerge from the Bayesian account, rather than being used to constrain priors and likelihoods. I provide a detailed discussion of the case of how the Copernican and Ptolemaic theories explain retrograde motion, and suggest that one of the key explanatory considerations is the extent to which the explanation a theory provides depends on its core elements rather than on auxiliary hypotheses. I then suggest that this type of consideration is reflected in the Bayesian likelihood, given priors that a Bayesian might be inclined to adopt even without explicit guidance by IBE. The aim is to show that IBE and Bayesianism may be compatible, not because they can be amalgamated, but rather because they capture substantially similar epistemic considerations. 1 Introduction2 Preliminaries3 Inference to the Best Explanation4 Bayesianism5 The Incompatibilist View : Inference to the Best Explanation Contradicts Bayesianism5. 1 Criticism of the incompatibilist view6 Constraint - Based Compatibilism6. 1 Criticism of constraint - based compatibilism7 Emergent Compatibilism7. 1 Analysis of inference to the best explanation7. 1. 1 Inference to the best explanation on specific hypotheses7. 1. 2 Inference to the best explanation on general theories7. 1. 3 Copernicus versus Ptolemy7. 1. 4 Explanatory virtues7. 1. 5 Summary7. 2 Bayesian account8 Conclusion. (shrink)

The term “historical epistemology” can be read in two different ways: (1) as referring to a program of ‘historicizing’ epistemology, in the sense of a critique of traditional epistemology’s tendency to gloss over historical context, or (2) as a manifesto of ‘epistemologizing’ history, i.e. as a critique of radical historicist and relativist approaches. In this paper I will defend a position in this second sense. I show that one can account for the historical development and diversity of science without disavowing (...) the relevance of a (normatively understood) epistemology and without denying the existence of human cognitive universals across historical and cultural differences. In support of my thesis, I draw on cognitive scientific research on causal and symbolic cognition, arguing that causal understanding constitutes a basic part of science, which, in the course of its development, becomes more and more superimposed by a culturally and historically variable symbolic superstructure. (shrink)

Why a hermeneutical philosophy of the natural sciences? It is necessary to address the philosophic crisis of realism vs relativism in the natural sciences. This crisis is seen as a part of the cultural crisis that Husserl and Heidegger identified and attributed to the hegemonic role of theoretical and calculative thought in Western societies. The role of theory is addressed using the hermeneutical circle to probe the origin of theoretic meaning in scientific cultural praxes. This is studied in Galileo's discovery (...) of the phases of Venus; the practice of measurement; the different theories and practices of space perception; the historicality and temporality of scientific research communities which ground paradigm change; and the process of discovery. The paper draws particularly from the work of Heidegger. Though envisaging all science and scholarship, the highlighted theme is research in the natural sciences. (shrink)

Hermeneutics, or interpretation, is concerned with the generation, transmission, and acceptance of meaning within the lifeworld, and was the original method of the human sciences stemming, from F. Schleiermacher and W. Dilthey. The `hermeneutic philosophy' refers mostly to Heidegger. This paper addresses natural science from the perspective of Heidegger's analysis of meaning and interpretation. Its purpose is to incorporate into the philosophy of science those aspects of historicality, culture, and tradition that are absent from the traditional analysis of theory and (...) explanation, to re-orient the current discussion about scientific realism around the hermeneutics of meaning and truth in science, and to establish some relationship between the current philosophy of natural science and hermeneutical philosophy. The paper has particular relevance to the history and social studies of science and technology. (shrink)

I offer an account of how the quantum theory we have helps us explain the enormous variety of phenomena it is generally taken to explain. The account depends on what I have elsewhere called a pragmatist interpretation of the theory. This rejects views according to which a quantum state describes or represents a physical system, holding instead that it functions as a source of sound advice to physically situated agents like us on the content and appropriate degree of belief about (...) matters concerning which they are currently inevitably ignorant. So while the account given here is incompatible with some views of structural explanation in quantum theory it is nevertheless able to incorporate what I take to be their valuable insights. (shrink)

Scientific theories are developed in response to a certain set of phenomena and subsequently evaluated, at least partially, in terms of the quality of fit between those same theories and appropriately distinctive phenomena. To differentiate between these two stages it is popular to describe the former as involving the accommodation of data and the latter as involving the prediction of data. Predictivism is the view that, ceteris paribus, correctly predicting data confers greater confirmation than successfully accommodating data. In this paper, (...) I take issue with a variety of predictivist theses, argue that their role for issues of confirmation is extremely limited, and attempt to account for the appeal that predictivism has enjoyed. Introduction Temporal Predictivism Heuristic Predictivism Weak Predictivism 4.1 Inference to better theories 4.2 Inference to better methods Arguments for Strong Heuristic Predictivism 5.1 Best explanations argument 5.2 Conditional support 5.3 Unique explanations Increased Explanatory Unification 6.1 Explaining what other theories can't 6.2 Contrived hypotheses 6.2 Strength and simplicity Conclusions CiteULike Connotea Del.icio.us What's this? (shrink)

This article examines how scientists move from physical measurementsto actual observation of single-cell recordings in the brain. We highlight how easy it is to change the fundamental nature of ourobservations using accepted methodological techniques for manipulatingraw data. Collecting single-cell data is thoroughly pragmatic. Weconclude that there is no deep or interesting difference betweenaccounting for observations by measurements and accounting forobservations by theories.

One of the reasons for relativistic attitudes toward science is the impossibility of justifying scientists’ decisions in the face of alternative theories. According to this paper, an alternative theory can challenge scientific rationality only if the conditions of “methodological shortcomings of scientists” and the “existence of alternative theories” are met at a specific time. A commonly used technique to counter relativism is to try to supplement and equip scientists’ methodologies when confronted with alternative theories. However, this paper focuses on evaluating (...) the possibility of “existence an alternative theory.” To this end, by referring to the different definitions of being alternative, we try to show that only “after the decision” and “the conversion of the scientific community” can a theory be considered justifiably “alternative.” Therefore, the relativistic claim is inconsistent because relativists must first accept the validity of scientists’ decisions to attribute being alternative to a theory. In this work, we provide evidence for our claim using a historical example. We also defend conservatism as a corollary of our discussion. (shrink)

This paper discusses Husserl’s views on physical theories in the first volume of his Logical Investigations, and compares them with those of his contemporaries Pierre Duhem and Henri Poincaré. Poincaré’s views serve as a bridge to a discussion of Husserl’s almost unknown views on physical geometry from about 1890 on, which in comparison even with Poincaré’s—not to say Frege’s—or almost any other philosopher of his time, represented a rupture with the philosophical tradition and were much more in tune with the (...) physical geometry underlying the Einstein-Hilbert general theory of relativity developed more than two decades later. (shrink)

Das obras de Newton da Costa, muitas pessoas na França conhecem apenas o renascimento da paraconsistência. Apresentamos algumas razões em defesa de investigações nessa parte da lógica. Acima de tudo, porém, relembramos uma das maiores contribuições de Newton da Costa: sua demonstração, em 1991, em colaboração com Doria, da indecidibilidade gödeliana do movimento na física matemátcia, um resultado que foi de certa forma previsto, por outras razões, por Duhem em 1906. DOI: 10.5007/1808-1711.2011v15n1p7.

Duhem’s philosophy of science is difficult to classify according to more contemporary categories like instrumentalism and realism. On the one hand, he presents an account of scientific methodology which renders theories as mere instruments. On the other hand, he acknowledges that theories with particular theoretical virtues offer a classification of experimental laws that “corresponds to real affinities among the things themselves.” In this paper, we argue that Duhem’s philosophy of science was motivated by an anti-sceptical tendency, according to which we (...) can confidently assert that our theories reveal truths about nature while, at the same time, admitting that anti-scepticism should be moderated by epistemic humility. Understanding Duhem’s epistemological position, which was unique amongst French philosophers of science in the beginning of the 20th century, requires a careful examination of his accounts of representation, explanation, and of their interrelation. (shrink)

Work on analogy has been done from a number of disciplinary perspectives throughout the history of Western thought. This work is a multidisciplinary guide to theorizing about analogy. It contains 1,406 references, primarily to journal articles and monographs, and primarily to English language material. classical through to contemporary sources are included. The work is classified into eight different sections (with a number of subsections). A brief introduction to each section is provided. Keywords and key expressions of importance to research on (...) analogy are discussed in the introductory material. Electronic resources for conducting research on analogy are listed as well. (shrink)

This paper concerns local yet systematic problems of contrastive underdetermination of model choice in cognitive neuroscience debates about the so-called two visual systems hypothesis. The underdetermination problem is systematically generated by the way certain assumptions about the representationalist nature of computation are translated into experimental practice. The problem is that behavioural data underdetermine the choice between competing representational models. In this paper, I diagnose how these assumptions generate underdetermination problems in the choice between competing functional models of perception–action. Using the (...) tools of philosophy of science, I describe the type of underdetermination and sketch a possible cure. (shrink)

Scientists use a variety of modes of representation in their work, but philosophers have studied mainly sentences expressing propositions. I ask whether diagrams are mere conveniences in expressing propositions or whether they are a distinct, ineliminable mode of representation in scientific texts. The case of path analysis, a statistical method for quantitatively assessing the relative degree of causal determination of variation as expressed in a causal path diagram, is discussed. Path analysis presents a worst case for arguments against eliminability since (...) path diagrams are usually presumed to be mathematically or logically “equivalent” in an important sense to sets of linear path equations. I argue that path diagrams are strongly generative, i.e., that they add analytical power to path analysis beyond what is supplied by linear equations, and therefore that they are ineliminable in a strong scientific sense. (shrink)

Accounts of the relation between theories and models in biology concentrate on mathematical models. In this paper I consider the dual role of models as representations of natural systems and as a material basis for theorizing. In order to explicate the dual role, I develop the concept of a remnant model, a material entity made from parts of the natural system(s) under study. I present a case study of an important but neglected naturalist, Joseph Grinnell, to illustrate the extent to (...) which mundane practices in a museum setting constitute theorizing. I speculate that historical and sociological analyses of institutions can play a specific role in the philosophical analysis of model-building strategies. (shrink)

(2000). CASSIRER, SCHLICK AND ‘STRUCTURAL’ REALISM: THE PHILOSOPHY OF THE EXACT SCIENCES IN THE BACKGROUND TO EARLY LOGICAL EMPIRICISM. British Journal for the History of Philosophy: Vol. 8, No. 1, pp. 71-106.

This paper characterizes the increase in ‘scientific understanding’ that resulted from the Ingold Revolution in organic chemistry. By describing both the sorts of explanations facilitated by Ingold’s Revolution and the sense in which organic chemistry was ‘unified’ by adopting these approaches to explanation, one can appreciate how this revolution led to a dramatic qualitative improvement in organic chemists’ understanding of the phenomena that they study. The explanatory unification responsible for this transformation in organic chemistry is contrasted with contemporary philosophical accounts (...) of unification and its relationship to both scientific understanding and explanation. (shrink)

W. V. Quine famously argues that though all knowledge is empirical, mathematics is entrenched relative to physics and the special sciences. Further, entrenchment accounts for the necessity of mathematics relative to these other disciplines. Michael Friedman challenges Quine’s view by appealing to historicism, the thesis that the nature of science is illuminated by taking into account its historical development. Friedman argues on historicist grounds that mathematical claims serve as principles constitutive of languages within which empirical claims in physics and the (...) special sciences can be formulated and tested, where these mathematical claims are themselves not empirical but conventional. For Friedman, their conventional, constitutive status accounts for the necessity of mathematics relative to these other disciplines. Here I evaluate Friedman’s challenge to Quine and Quine’s likely response. I then show that though we have reason to find Friedman’s challenge successful, his positive project requires further development before we can endorse it. (shrink)

Pierre Duhem rejected unambiguously the strong version of realism that he believed was held by Copernicus. In fact, although Copernicus believed that his theory was clearly superior to Ptolemy's, he seems to have recognized that his theory was at best only approximately true. Accordingly, he recognized that his arguments were not demonstrative in the traditional sense but probable and persuasive. Duhem regarded even the belief in probably true explanations as misguided. Nevertheless, Duhem recognized that, even if metaphysical intuition does not (...) enter into the content of physical theories, the rejection of hypotheses could be explained only by appeal to common sense. Hence, Duhem held a qualified instrumentalism according to which physical theories are not realist, but the terms of ordinary experience and empirical laws are realist. Accordingly, Duhem rejected the complete subordination of science to philosophy as well as the complete separation of science from philosophy. Duhem's history of cosmological doctrines reflects his belief in the origin of the subordination of science to philosophy and of the struggle to achieve the proper balance without being driven to the opposite extreme of their complete separation. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 10.2 (2005) 75-99 [Access article in PDF] Gynocentric Eco-Logics Trish Glazebrook All of our teachings come from things in nature, they come from the growing cycle, and everything is tied to the earth.1Ludwig Fleck describes in his Genesis and Development of a Scientific Fact how the concept of syphilis is "a result of the development and confluence of several lines of collective thought" (Fleck 1979, (...) 23). Diagnosis and treatment of the disease required that its symptomatology undergo transformation from "an undifferentiated and confused mass of information about chronic diseases characterized by skin symptoms" (1979, 1) into the concept of a single disease. Identifying the Spirochaeta pallida bacterium and diagnosing syphilis by means of the Wasserman reaction was only possible when an unclearly related collection of symptoms could be experienced as belonging together in a unified phenomenology.Likewise, I wish to provide a diagnosis and etiology, and suggest a curative possibility for a disease of modernity I will call phallic logic. Symptomatic of this sickness are wide-spread social alienation, global domination and oppression on the basis of gender, race, class and color, and epidemic eco-destruction. A body of critique exists in ecofeminist analyses that experiences these symptoms as a single disease: the phallic logic of modernity. "Logic" in this context does not mean the formal discipline [End Page 75] in which rules for the proper manipulation of abstract statements are laid down. Rather, "logic" in the sense used here is an epistemological term. It means the ways that understanding is structured. Phallic logic is the structure of understanding that permeates patriarchy. This logic takes its paradigm from scientific objectivity, but even voices from within the sciences themselves are arguing that contemporary human being must establish new ways of thinking about nature.I propose that such new eco-logics, that is, ways of thinking about nature, take their guidance from the physical environment. If nature informs knowledge claims, then knowledge itself is construed organically: it is finite and changing rather than fixed and eternal. Such logics can encompass the finitude of physical embodiment as an epistemological principle, and hence I identify them as gynocentric. They are not grounded in the disembodied Cartesian subject that feminists have shown so often and clearly to be typical of androcentric philosophizing. These logics draw instead on the physicality of environmental elements as well as of the thinker, and thus they allow nature's temporality to resonate within knowledge itself. They are not satisfied with a conceptual contrast between nature's on-going coming-to-be and passing-away and the alleged universality of knowledge. Rather, they take nature as a model for truth and acknowledge that nature infuses the things we say to be truth.There is an abundance of arguments for the differences between male and female writing and thinking.2 I speak in accord with these voices, but I frame my project differently. I will begin by presenting evidence of a call for alternative epistemologies from within the sciences, and then use ecofeminist analyses to argue that the scientists in question are moving away from a phallic logic toward gynocentric eco-logics. Next I will make clear three assumptions that underlie my account. The first two are Heideggerian. I accept his argument that the logic of modernity is scientific objectivity, and I use his account of truth and essence to argue that knowledge is situated rather than universal. Hence gynocentric eco-logics entail an essentialism that is historical rather than biological. I give up biology as the fixative for essence, but avoid a decline into what is entirely arbitrary and subjective by fixing essence in terms of cultural and historical location. Hence I am using a Heideggerian notion of situatedness, but applying it specifically to gender such that I can maintain that the category of "woman" is neither universal, nor shattered irreparably into [End Page 76] fragmented individualism. My Heideggerianism is further qualified in that I am not writing in the spirit of Heidegger's life-time project. I will take the force of his insights to be epistemological rather than metaphysical or ontological... (shrink)

In the epistemological tradition, there are two main interpretations of the semantic relation that an empirical theory may bear to the real world. According to realism, the theory-world relationship should be conceived as truth; according to instrumentalism, instead, it should be limited to empirical adequacy. Then, depending on how empirical theories are conceived, either syntactically as a class of sentences, or semantically as a class of models, the concepts of truth and empirical adequacy assume different and specific forms. In this (...) paper, we review two main conceptions of truth (one sentence-based and one model-based) and two of empirical adequacy (one sentence-based and one model-based), we point out their respective difficulties, and we give a first formulation of a new general view of the theory-world relationship, which we call Methodological Constructive Realism (MCR). We then show how the content of MCR can be further specified and expressed in a definite and precise form. The bulk of the paper shows in detail how it is possible to accomplish this goal for the special case of deterministic dynamical phenomena and their correlated deterministic models. This special version of MCR is formulated as an axiomatic extension of set theory, whose specific axioms constitute a formal ontology that provides an adequate framework for analyzing the two semantic relations of truth and empirical correctness, as well as their connections. (shrink)

This paper questions and criticizes the employment of critical realism in the field of ‘science and religion’. Referring to the texts of four main actors in this field, I demonstrate how the choice of critical realism is justified by a (disguised) apologetic interest in defending the epistemic privilege of the theological enterprise against that of the natural sciences. I argue that this is possible thanks to the reactivation of ‘theological potential’ latent in some under-examined assumptions and conceptual structures still at (...) work within philosophy of science and scientific epistemology. (shrink)

This study considers the short list of Nature of Science features frequently published and widely known in the science education discourse. It is argued that these features were oversimplified and a refinement of the claims may enrich or sometimes reverse them. The analysis shows the need to address the range of variation in each particular aspect of NOS and to illustrate these variations with actual events from the history of science in order to adequately present the subject. Another implication of (...) the proposal is the highlighting of the central role of science educators who, facing various strong claims of researchers in education and philosophy of science, often have difficulty in making a choice of what to teach about NOS. It is suggested that a representative variation with regard to the traditional NOS claims may be appropriate for a genuine understanding of the subject. In that, using the discipline-culture structure of the fundamental theories of physics and addressing the plurality of scientific methods may be helpful in the actual teaching and learning of NOS. (shrink)

Philip Tetlock underestimates the import of his own Expert Political Judgment. It is much more than a critical scientific evaluation of the accuracy and consistency of political pundits. It also offers a blueprint for challenging expertise more generally-in the name of scientific advancement. “Thinking the unthinkable”-a strategy Tetlock employs when he gets experts to consider counterfactual scenarios that are far from their epistemic comfort zones-has had explosive consequences historically for both knowledge and morality by extending our sense of what is (...) possible. Thinking the unthinkable might also put into question contemporary assumptions about the legitimacy of science. (shrink)

Scientific hypotheses may either predict particular unknown facts or accommodate previously-known data. Although affirmed predictions are intuitively more rewarding than accommodations of established facts, opinions divide whether predictive hypotheses are also epistemically superior to accommodation hypotheses. This paper examines the contribution of predictive hypotheses to discoveries of several bio-molecular systems. Having all the necessary elements of the system known beforehand, an abstract predictive hypothesis of semiconservative mode of DNA replication was successfully affirmed. However, in defining the genetic code whose biochemical (...) basis was unclear, hypotheses were only partially effective and supplementary experimentation was required for its conclusive definition. Markedly, hypotheses were entirely inept in predicting workings of complex systems that included unknown elements. Thus, hypotheses did not predict the existence and function of mRNA, the multiple unidentified components of the protein biosynthesis machinery, or the manifold unknown constituents of the ubiquitin–proteasome system of protein breakdown. Consequently, because of their inability to envision unknown entities, predictive hypotheses did not contribute to the elucidation of cation theories remained the sole instrument to explain complex bio-molecular systems, the philosophical question of alleged advantage of predictive over accommodative hypotheses became inconsequential. (shrink)

Philosophers of science diverge on the question what drives the growth of scientific knowledge. Most of the twentieth century was dominated by the notion that theories propel that growth whereas experiments play secondary roles of operating within the theoretical framework or testing theoretical predictions. New experimentalism, a school of thought pioneered by Ian Hacking in the early 1980s, challenged this view by arguing that theory-free exploratory experimentation may in many cases effectively probe nature and potentially spawn higher evidence-based theories. Because (...) theories are often powerless to envisage workings of complex biological systems, theory-independent experimentation is common in the life sciences. Some such experiments are triggered by compelling observation, others are prompted by innovative techniques or instruments, whereas different investigations query big data to identify regularities and underlying organizing principles. A distinct fourth type of experiments is motivated by a major question. Here I describe two question-guided experimental discoveries in biochemistry: the cyclic adenosine monophosphate mediator of hormone action and the ubiquitin-mediated system of protein degradation. Lacking underlying theories, antecedent data bases, or new techniques, the sole guides of the two discoveries were respective substantial questions. Both research projects were similarly instigated by theory-free exploratory experimentation and continued in alternating phases of results-based interim working hypotheses, their examination by experiment, provisional hypotheses again, and so on. These two cases designate theory-free, question-guided, stepwise biochemical investigations as a distinct subtype of the new experimentalism mode of scientific enquiry. (shrink)

Everything you always wanted to know about structural realism but were afraid to ask Content Type Journal Article Pages 227-276 DOI 10.1007/s13194-011-0025-7 Authors Roman Frigg, Department of Philosophy, Logic and Scientific Method, London School of Economics and Political Science, Houghton Street, London, WC2A 2AE UK Ioannis Votsis, Philosophisches Institut, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, Geb. 23.21/04.86, 40225 Düsseldorf, Germany Journal European Journal for Philosophy of Science Online ISSN 1879-4920 Print ISSN 1879-4912 Journal Volume Volume 1 Journal Issue Volume 1, Number 2.

William Whewell’s philosophy of scientific discovery is applied to the problem of understanding the nature of unification and explanation by the composition of causes in Newtonian mechanics. The essay attempts to demonstrate: the sense in which ”approximate’ laws successfully refer to real physical systems rather than to idealizations of them; why good theoretical constructs are not badly underdetermined by observation; and why, in particular, Newtonian forces are not conventional and how empiricist arguments against the existence of component causes, and against (...) the veracity of the fundamental laws, are flawed. (shrink)

It has become apparent that the debate between scientific realists and constructive empiricists has come to a stalemate. Neither view can reasonably claim to be the most rational philosophy of science, exclusively capable of making sense of all scientific activities. On one prominent analysis of the situation, whether we accept a realist or an anti-realist account of science actually seems to depend on which values we antecedently accept, rather than our commitment to “rationality” per se. Accordingly, several philosophers have attempted (...) to argue in favour of scientific realism or constructive empiricism by showing that one set of values is exclusively best, for anyone and everyone, and that the downstream choice of the philosophy of science which best serves those values is therefore best, for anyone and everyone. These efforts, however, seem to have failed. In response, I suggest that philosophers of science should suspend the effort to determine which philosophy of science is best for everyone, and instead begin investigating which philosophy of science is best for specific people, with specific values, in specific contexts. I illustrate how this might be done by briefly sketching a single case study from the history of science, which seems to show that different philosophies of science are better at motivating different forms of scientific practice. (shrink)

Discussion of epistemic responsibility typically focuses on belief formation and actions leading to it. Similarly, accounts of collective epistemic responsibility have addressed the issue of collective belief formation and associated actions. However, there has been little discussion of collective responsibility for preventing epistemic harms, particularly those preventable only by the collective action of an unorganized group. We propose an account of collective epistemic responsibility which fills this gap. Building on Hindriks' (2019) account of collective moral responsibility, we introduce the Epistemic (...) Duty to Join Forces. Our theory provides an account of the responsibilities of scientists to prevent epistemic harms during inquiry. (shrink)