(Recipient of the 2020 Everett Mendelsohn Prize.) This article revisits the development of the protoplasm concept as it originally arose from critiques of the cell theory, and examines how the term “protoplasm” transformed from a botanical term of art in the 1840s to the so-called “living substance” and “the physical basis of life” two decades later. I show that there were two major shifts in biological materialism that needed to occur before protoplasm theory could be elevated to have equal status (...) with cell theory in the nineteenth century. First, I argue that biologists had to accept that life could inhere in matter alone, regardless of form. Second, I argue that in the 1840s, ideas of what formless, biological matter was capable of dramatically changed: going from a “coagulation paradigm” that had existed since Theophrastus, to a more robust conception of matter that was itself capable of movement and self-maintenance. In addition to revisiting Schleiden and Schwann’s original writings on cell theory, this article looks especially closely at Hugo von Mohl’s definition of the protoplasm concept in 1846, how it differed from his primordial utricle theory of cell structure two years earlier. This article draws on Lakoff and Johnson’s theory of “ontological metaphors” to show that the cell, primordial utricle, and protoplasm can be understood as material container, object, and substance, and that these overlapping distinctions help explain the chaotic and confusing early history of cell theory. (shrink)

Peter Ludlow presents the first book on the philosophy of generative linguistics, including both Chomsky's government and binding theory and his minimalist ...

As Peter Niebyl has documented, one of the issues in which the Wittenberg-based physician and philosopher Daniel Sennert (1572–1637) departed from Paracelsus and his followers was the concept of disease. Paracelsus and some of his followers regarded diseases as real beings—so-called “disease-entities” (entia morbis) that can enter into the body of a living being and thereafter possess a clearly defined location in the affected organism. 1 For Sennert, such a view is a dangerous confusion between disease and its causes. According (...) to him, causes of disease can be present in an organism without actually causing a disease (Sennert 1629, p. 253). Moreover, he shares the traditional Christian doctrine .. (shrink)

Chemistry is the study of the structure and transformation of matter. When Aristotle founded the field in the 4th century BCE, his conceptual grasp of the nature of matter was tailored to accommodate a relatively simple range of observable phenomena. In the 21st century, chemistry has become the largest scientific discipline, producing over half a million publications a year ranging from direct empirical investigations to substantial theoretical work. However, the specialized interest in the conceptual issues arising in chemistry, hereafter Philosophy (...) of Chemistry, is a relatively recent addition to philosophy of science. Philosophy of chemistry has two major parts. In the first, conceptual issues arising within chemistry are carefully articulated and analyzed. Such questions which are internal to chemistry include the nature of substance, atomism, the chemical bond, and synthesis. In the second, traditional topics in philosophy of science such as realism, reduction, explanation, confirmation, and modeling are taken up within the context of chemistry. (shrink)

This paper investigates the relationship between some corpuscularian and Aristotelian strands that run through the thought of the sixteenth-century philosopher and physician Julius Caesar Scaliger. Scaliger often uses the concepts of corpuscles, pores, and vacuum. At the same time, he also describes mixture as involving the fusion of particles into a continuous body. The paper explores how Scaliger’s combination of corpuscularian and non-corpuscularian views is shaped, in substantial aspects, by his response to the views on corpuscles and the vacuum in (...) the work of his contemporary, Girolamo Fracastoro. Fracastoro frequently appears in Scaliger’s work as an opponent against whom numerous objections are directed. However, if one follows up Scaliger’s references, it soon becomes clear that Scaliger also shares some of Fracastoro’s views. Like Scaliger, Fracastoro suggests corpuscularian explanations of phenomena such as water rising in lime while at the same time ascribing some non-corpuscularian properties to his natural minima. Like Scaliger, Fracastoro maintains that there is no vacuum devoid of bodies since places cannot exist independently of bodies (although their opinions diverge regarding how exactly the relevant dependency relation might be explicated). Finally, like Scaliger, Fracastoro connects a continuum view of mixture with a theory of natural minima. (shrink)

The term philosophy of chemistry is here construed broadly to include some publications from the history of chemistry and chemical education. Of course this initial selection of material has inevitably been biased by the interests of the author. This bibliography supersedes that of van Brakel and Vermeeren (1981), although no attempt has been made to include every single one of their entries, especially in languages other than English. Also, readers interested particularly in articles in German may wish to consult the (...) bibliography by Dittus and Mayer which also contains some material not included here (Dittus and Mayer, 1992). The aim is to maintain an up-to-date version of this bibliography and to publish a revised version in due course. Suggestions for further inclusions should be sent to the author. (shrink)

Philosophers today have largely given up on the project of categorizing being. Aristotle’s ten categories now strike us as quaint, and no attempt to improve on that effort meets with much interest. Still, no one supposes that reality is smoothly distributed over space. The world at large comes in chunks, and there remains a widespread intuition, even among philosophers, that some of these chunks have a special sort of unity and persistence. These, we tend to suppose, are most truly agents (...) and subjects, and are what exist in the most proper sense of the term. We believe, in other words, in substances. (shrink)

While the tradition of Locke scholarship holds that both Locke and Boyle are species anti-realists, there is evidence that this interpretation is false. Specifically, there has been some recent work on Boyle showing that he is, unlike Locke, a species realist. In this paper I argue that once we see Boyle as a realist about natural species, it is plausible to read some of Locke’s most formidable anti-realist arguments as directed specifically at Boyle’s account of natural species. This is a (...) break from the tradition because no one in the literature has yet suggested that some of Locke’s arguments in Book III of the Essay include a criticism of Boyle’s doctrine of species. Moreover, identifying Boyle as Locke’s intended target illuminates some of the more vexing passages in the Essay concerning real essences. (shrink)

This paper studies Robert Boyle's account of kinds and classification. A number of commentators have argued that, for Boyle, classifications are inevitably the product of conventions. Others have challenged this reading, arguing that, according to Boyle, the corpuscular makeup of bodies gives rise to hard-edged natural kinds and classes. We argue that Boyle's position is more complicated than the available realist and conventionalist readings acknowledge. We argue that, according to Boyle, the individuation of kinds was to some degree the result (...) of convention. At the same time, however, Boyle held that our classificatory practices are subject to constraints. We identify some of these constraints by turning to Boyle's discussion of the late scholastic debate about the plurality of forms, in particular the contributions of Jacopo Zabarella and Daniel Sennert. In this way, we clarify how Boyle strikes a balance between realist and conventionalist elements in his treatment of kinds. (shrink)

The aim of this text is to investigate a little-known aspect of John Locke’s work: the relationship between philosophy and his medical practice. This theme is justified because his philosophical conception is widely known, but his studies in the field of medicine are practically ignored in Brazil. To accomplish this task, the article is divided into threeparts: in the first, we will address the debate on English medical practice in the seventeenth century; in the second, Locke’s penchant for medicine and, (...) finally, in the third, Locke’s medical practice. We hope that this text can contribute to the advancement of research on John Locke in Brazil,especially on his relationship with medicine. (shrink)

We summarize in this introduction the contents of all the contributions included in Synthese special issue on form, structure and hylomorphism. Moreover, we provide an exhaustive bibliography of recent research on these topics.

The ArugmentThis essay answers a single question: what was Robert Hooke, the Royal Society's curator of experiments, doing in his well-known 1665 work,Micrographia?Hooke was articulating a “universal cure of the mind” capable of bringing about a “reformation in Philosophy,” a change in philosophy's interpretive practices and organization. The work explicated the interpretive and political foundations for a community of optical instrument users coextensive with the struggling Royal Society. Standard observational practices would overcome the problem of using nonstandard instruments, while inherent (...) inrepresentation– the interpretive practice championed in the text – were important theological and political meanings. Hooke's kind of experimental philosophy undermined the claims made by “atheists” and “enthusiasts” – the enemies of the restored church and state – while also producing useful knowledge. Equally important, Hooke modeled the community described inMicrographiaupon the classicalres publica, but his community made important concessions to Restoration political realities, especially the growing role of commercial or transactional relationships. (shrink)

. The concept of bodily health is problematic for mechanists like Descartes, as it seems that they need to appeal to something extrinsic to a machine, i.e., its purpose, to determine whether the machine is working well or badly, and so healthy or unhealthy. I take issue with this claim. By drawing on the history of medicine, I suggest that in the seventeenth century there was space for a non-teleological account of health. I further argue that mechanists can and did (...) appeal to structural integrity, as a non-teleological notion of form, to ground the norms required for ascriptions of health. (shrink)