Mizrahi’s argument against Stanford’s challenge to scientific realism is analyzed. Mizrahi’s argument is worth of attention for at least two reasons: unlike other criticisms that have been made to Stanford’s view so far, Mizrahi’s argument does not question any specific claim of Stanford’s argument, rather it puts into question the very coherence of Stanford’s position, because it argues that since Stanford’s argument rests on the problem of the unconceived alternatives, Stanford’s argument is self-defeating. Thus, if Mizrahi’s argument is effective in (...) countering Stanford’s view, it may be able to question the validity of other philosophical positions which similarly rest on the problem of the unconceived alternatives; Mizrahi’s argument against Stanford’s view is in part based on the development of a Stanford-like argument for the field of philosophy. This makes Mizrahi’s argument potentially relevant to the metaphilosophical debate. After careful examination, Mizrahi’s argument against Stanford’s instrumentalism is found wanting. Moreover, a Stanford-like argument is developed, which aims at challenging the metaphilosophical stance implied by Mizrahi’s argument against Stanford’s instrumentalism. (shrink)

Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data as possible. We think instead (...) that a deeper understanding of cancer can be achieved by means of more theoretical work, rather than by merely accumulating more data. To support our thesis, we introduce the analytic view of theory development, which rests on the concept of plausibility, and make clear in what sense plausibility and probability are distinct concepts. Then, the concept of plausibility is used to point out the ineliminable role played by the epistemic subject in the development of statistical tools and in the process of theory assessment. We then move to address a central issue in cancer research, namely the relevance of computational tools developed by bioinformaticists to detect driver mutations in the debate between the two main rival theories of carcinogenesis. Finally, we briefly extend our considerations on the role that plausibility plays in evidence amalgamation from cancer research to the more general issue of the divergences between frequentists and Bayesians in the philosophy of medicine and statistics. We argue that taking into account plausibility-based considerations can lead to clarify some epistemological shortcomings that afflict both these perspectives. (shrink)

In this paper, I outline a reductio against Stanford’s “New Induction” on the History of Science, which is an inductive argument against scientific realism that is based on what Stanford (2006) calls “the Problem of Unconceived Alternatives” (PUA). From the supposition that Stanford’s New Induction on the History of Science is cogent, and the parallel New Induction on the History of Philosophy (Mizrahi 2014), it follows that scientific antirealism is not worthy of belief. I also show that denying a key (...) premise in the reductio only forces antirealists who endorse Stanford’s New Induction on the History of Science into a dilemma: either antirealism falls under the axe of Stanford’s New Induction on the History of Science or it falls under the axe of the New Induction on the History of Philosophy. (shrink)

Plakias has recently argued that there is nothing wrong with publishing defences of philosophical claims which we don't believe and also nothing wrong with concealing our lack of belief, because an author's lack of belief is irrelevant to the merit of a published work. Fleisher has refined this account by limiting the permissibility of publishing without belief to what he calls ‘advocacy role cases’. I argue that such lack of belief is irrelevant only if it is the result of an (...) inexplicable incredulity or the result of a metaphilosophical or epistemic stance that is unrelated to the specific claim. However, in many real-life cases, including Fleisher's advocacy role cases, our doubts regarding the claims we defend arise from reasons that have something to do with the insufficiency of the philosophical evidence supporting the claim, and publishing an unconditional defence of a claim without revealing our doubts is impermissible as it involves withholding philosophically relevant reasons. Plakias has also argued that discouraging philosophers from publishing claims they don't believe would be unfair to junior philosophers with unsettled views. I propose that we should change our academic practices that pressure philosophers to publish articles that pretend to be defences of settled views. (shrink)

This thesis justifies the need for and develops a new integrated model of practical reasoning and argumentation. After framing the work in terms of what is reasonable rather than what is rational (chapter 1), I apply the model for practical argumentation analysis and evaluation provided by Fairclough and Fairclough (2012) to a paradigm case of unreasonable individual practical argumentation provided by mass murderer Anders Behring Breivik (chapter 2). The application shows that by following the model, Breivik is relatively easily able (...) to conclude that his reasoning to mass murder is reasonable – which is understood to be an unacceptable result. Causes for the model to allow such a conclusion are identified as conceptual confusions ingrained in the model, a tension in how values function within the model, and a lack of creativity from Breivik. Distinguishing between dialectical and dialogical, reasoning and argumentation, for individual and multiple participants, chapter 3 addresses these conceptual confusions and helps lay the foundation for the design of a new integrated model for practical reasoning and argumentation (chapter 4). After laying out the theoretical aspects of the new model, it is then used to re-test Breivik’s reasoning in light of a developed discussion regarding the motivation for the new place and role of moral considerations (chapter 5). The application of the new model shows ways that Breivik could have been able to conclude that his practical argumentation was unreasonable and is thus argued to have improved upon the Fairclough and Fairclough model. It is acknowledged, however, that since the model cannot guarantee a reasonable conclusion, improving the critical creative capacity of the individual using it is also of paramount importance (chapter 6). The thesis concludes by discussing the contemporary importance of improving practical reasoning and by pointing to areas for further research (chapter 7). (shrink)