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Drug Regulation and the Inductive Risk Calculus

In Kevin Christopher Elliott & Ted Richards (eds.), Exploring Inductive Risk: Case Studies of Values in Science. New York: Oup Usa. pp. 17-36 (2017)

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  1. What are Side Effects?Austin Due - 2023 - European Journal for Philosophy of Science 13 (1):1-21.
    Side effects are ubiquitous in medicine and they often play a role in treatment decisions for patients and clinicians alike. Philosophers and health researchers often use side effects to illustrate issues with contemporary medical research and practice. However, technical definitions of ‘side effect’ differ among health authorities. Thus, determining the side effects of an intervention can differ depending on whose definition we assume. Here I review some of the common definitions of side effect and highlight their issues. In response, I (...)
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  • On the mitigation of inductive risk.Gabriele Contessa - 2021 - European Journal for Philosophy of Science 11 (3):1-14.
    The last couple of decades have witnessed a renewed interest in the notion of inductive risk among philosophers of science. However, while it is possible to find a number of suggestions about the mitigation of inductive risk in the literature, so far these suggestions have been mostly relegated to vague marginal remarks. This paper aims to lay the groundwork for a more systematic discussion of the mitigation of inductive risk. In particular, I consider two approaches to the mitigation of inductive (...)
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  • Are Experts Representative of Non-Experts? Elective Modernism, Aspects of Representation, and the Argument from Inductive Risk.Jaana Eigi - 2020 - Perspectives on Science 28 (4):459-481.
    The approach to expert communities and political representation of non-experts in Harry Collins and Robert Evans’ elective modernism reflects the conviction that experts are not representative of ordinary citizens. I use an analysis of aspects of representation and the argument from inductive risk to argue that experts can be seen as representative of non-experts, when we understand representation as resemblance based on shared social perspectives and acknowledge the inevitable involvement of such perspectives in decisions under inductive risk. This, in turn, (...)
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  • Treatment Effectiveness and the Russo–Williamson Thesis, EBM+, and Bradford Hill's Viewpoints.Steven Tresker - 2021 - International Studies in the Philosophy of Science 34 (3):131-158.
    Establishing the effectiveness of medical treatments is one of the most important aspects of medical practice. Bradford Hill's viewpoints play an important role in inferring causality in medicine,...
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  • Inductive Risk and OxyContin: The Ethics of Evidence and Post-Market Surveillance of Pharmaceuticals in Canada.Itai Bavli & Daniel Steel - 2020 - Public Health Ethics 13 (3):300-313.
    The argument from inductive risk claims that judgments about the moral severity of errors are relevant to decisions about what should count as sufficient evidence for accepting claims. While this idea has been explored in connection with evidence required for the approval of pharmaceuticals, the role of inductive risk in the post-approval process has been largely neglected. In this article, we examine the ethics of inductive risk in connection with revisions to the product monograph for OxyContin in Canada, which understates (...)
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