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  1. A Pressure-Reversible Cellular Mechanism of General Anesthetics Capable of Altering a Possible Mechanism of Consciousness.Kunjumon Vadakkan - 2015 - Springerplus 4:1-17.
    Different anesthetics are known to modulate different types of membrane-bound receptors. Their common mechanism of action is expected to alter the mechanism for consciousness. Consciousness is hypothesized as the integral of all the units of internal sensations induced by reactivation of inter-postsynaptic membrane functional LINKs during mechanisms that lead to oscillating potentials. The thermodynamics of the spontaneous lateral curvature of lipid membranes induced by lipophilic anesthetics can lead to the formation of non-specific inter-postsynaptic membrane functional LINKs by different mechanisms. These (...)
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  • A Framework for the First‑Person Internal Sensation of Visual Perception in Mammals and a Comparable Circuitry for Olfactory Perception in Drosophila.Kunjumon Vadakkan - 2015 - Springerplus 4 (833):1-23.
    Perception is a first-person internal sensation induced within the nervous system at the time of arrival of sensory stimuli from objects in the environment. Lack of access to the first-person properties has limited viewing perception as an emergent property and it is currently being studied using third-person observed findings from various levels. One feasible approach to understand its mechanism is to build a hypothesis for the specific conditions and required circuit features of the nodal points where the mechanistic operation of (...)
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  • Framework of Consciousness From Semblance of Activity at Functionally LINKed Postsynaptic Membranes.Kunjumon I. Vadakkan - 2010 - Frontiers in Psychology 1.
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  • The Thalamic Dynamic Core Theory of Conscious Experience.Lawrence M. Ward - 2011 - Consciousness and Cognition 20 (2):464-486.
    I propose that primary conscious awareness arises from synchronized activity in dendrites of neurons in dorsal thalamic nuclei, mediated particularly by inhibitory interactions with thalamic reticular neurons. In support, I offer four evidential pillars: consciousness is restricted to the results of cortical computations; thalamus is the common locus of action of brain injury in vegetative state and of general anesthetics; the anatomy and physiology of the thalamus imply a central role in consciousness; neural synchronization is a neural correlate of consciousness.
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