A theory of biological pattern formation

Download Edit this record How to cite View on PhilPapers
Abstract
The paper addresses the formation of striking patterns within originally near-homogenous tissue, the process prototypical for embryology, and represented in particularly purist form by cut sections of hydra regenerating, by internal reorganisation of the pre-existing tissue, a complete animal with head and foot. The essential requirements are autocatalytic, self-enhancing activation, combined with inhibitory or depletion effects of wider range – “lateral inhibition”. Not only de-novo-pattern formation, but also well known, striking features of developmental regulation such as induction, inhibition, and proportion regulation can be explained on this basis. The theory provides a mathematical recipe for the construction of molecular models with criteria for the necessary non-linear interactions. It has since been widely applied to different developmental processes.
PhilPapers/Archive ID
GIEATO-2
Upload history
Archival date: 2015-05-25
View other versions
Added to PP index
2015-05-25

Total views
1,604 ( #1,905 of 56,905 )

Recent downloads (6 months)
69 ( #10,109 of 56,905 )

How can I increase my downloads?

Downloads since first upload
This graph includes both downloads from PhilArchive and clicks on external links on PhilPapers.