The role of the physiological processes involved in human vision escapes clarification in current literature. Many unanswered questions about vision include: 1) whether there is more to lateral inhibition than previously proposed, 2) the role of the discs in rods and cones, 3) how inverted images on the retina are converted to erect images for visual perception, 4) what portion of the image formed on the retina is actually processed in the brain, 5) the reason we have an (...) after-image with antagonistic colors, and 6) how we remember space. This theoretical article attempts to clarify some of the physiological processes involved with human vision. The global integration of visual information is conceptual; therefore, we include illustrations to present our theory. Universally, the eyeball is 2.4 cm and works together with membrane potential, correspondingly representing the retinal layers,photoreceptors, and cortex. Images formed within the photoreceptors must first be converted into chemical signals on the photoreceptors’ individual discs and the signals at each disc are transduced from light photons into electrical signals. We contend that the discs code the electrical signals into accurate distances and are shown in our figures. The pre-existing oscillations among the various cortices including the striate and parietal cortex,and the retina work in unison to create an infrastructure of visual space that functionally ‘‘places” the objects within this ‘‘neural” space. The horizontal layers integrate all discs accurately to create a retina that is pre-coded for distance. Our theory suggests image inversion never takes place on the retina,but rather images fall onto the retina as compressed and coiled, then amplified through lateral inhibition through intensification and amplification on the OFF-center cones. The intensified and amplified images are decompressed and expanded in the brain, which become the images we perceive as external vision. (shrink)

From the beginning of time, humans believed they were the center of the universe. Such important beings could be nowhere else than at the very epicenter of existence, with all the other things revolving around them. Was this an arrogant position? Only time will tell. What is certain is that as some people were so certain of their significance, aeons later some other people became too confident in their unimportance. In such a context, the Earth quickly lost its privileged position (...) at the center of the universe and along with this, the ideas of absolute motion and time became unbearable for the modern intellect, which saw nothing but relativeness in everything. After years of accepting the ideas of relativity at face value without doubting them, scientists are now mature enough to start questioning everything as any true scientist would do, including their own basic assumptions. And one would be surprised to see that the basic assumptions of today’s science in physics (and cosmology alike) are based on philosophically dogmatic beliefs that humans are nothing more than insignificant specks of dust. These specks cannot be in any privileged position in the cosmos, nor can their frames of reference. These specks cannot be living on a planet that is not moving while everything else is. There can be no hint of our importance whatsoever. Hence, the Copernican principle that has poisoned scientific thinking for aeons now. When one analyzes the evidence provided by science to support the idea of relativity though, he would see that the same evidence can more easily and simply fit into a model where the Earth stands still. Yet, scientists preferred to revamp all physics by introducing the totally unintuitive ides of relativity – including the absolute limit of the speed of light – than even admitting the possibility of humans having any notion of central position in the cosmos. True scientists though should examine all possible explanations, including those that do not fit their beliefs. To the dismay of so many modern scientists who blindly believe the validity of the theory of relativity at face value, the movement towards a true and honest post-modern science where all assumptions are questioned, necessarily passes through a place where the Earth we live in stands still. Non-relativistic explanations of the Michelson Morley experiment, related to a motionless Earth or to ether, are viable alternatives that deserve their place in modern scientific thought. (shrink)

In the 1980s, physiologist Benjamin Libet conducted a series of ex-periments to test whether the will is free. Whilst he originally assumed that the will functions like an immaterial initiator of cerebral processes culminating in actions, he later began to think that it rather works like an immaterial veto inhib-iting unwanted actions by preventing unconsciously initiated cerebral processes from unfolding. Libet’s veto was widely criticized for its Cartesian dualist and interactionist implications. However, in 2016, Schultze-Kraft et al. adopted Libet’s idea (...) of an action-inhibiting veto and conducted a new experiment. Its goal was to test until which moment agents can inhibit an action that they already intended to do. Despite insisting on the material nature of the veto, the researchers also described the function of the veto in interactionist terms, namely as an act of the agent performed against her own cerebral processes. The purpose of this pa-per is to explain in which sense the veto in Libet’s and in Schultze-Kraft’s study is interactionist, and to provide a non-interactionist reinterpretation of the test subjects’ action inhibition in Schultze-Kraft’s experiment. (shrink)

The paper addresses the formation of striking patterns within originally near-homogenous tissue, the process prototypical for embryology, and represented in particularly purist form by cut sections of hydra regenerating, by internal reorganisation of the pre-existing tissue, a complete animal with head and foot. The essential requirements are autocatalytic, self-enhancing activation, combined with inhibitory or depletion effects of wider range – “lateral inhibition”. Not only de-novo-pattern formation, but also well known, striking features of developmental regulation such as induction, (...) class='Hi'>inhibition, and proportion regulation can be explained on this basis. The theory provides a mathematical recipe for the construction of molecular models with criteria for the necessary non-linear interactions. It has since been widely applied to different developmental processes. (shrink)

While many different mechanisms contribute to the generation of spatial order in biological development, the formation of morphogenetic fields which in turn direct cell responses giving rise to pattern and form are of major importance and essential for embryogenesis and regeneration. Most likely the fields represent concentration patterns of substances produced by molecular kinetics. Short range autocatalytic activation in conjunction with longer range “lateral” inhibition or depletion effects is capable of generating such patterns (Gierer and Meinhardt, 1972). Non-linear (...) reactions are required, and mathematical criteria were derived to design molecular models capable of pattern generation. The classical embryological feature of proportion regulation can be incorporated into the models. The conditions are mathematically necessary for the simplest two-factor case, and are likely to be a fair approximation in multi-component systems in which activation and inhibition are systems parameters subsuming the action of several agents. Gradients, symmetric and periodic patterns, in one or two dimensions, stable or pulsing in time, can be generated on this basis. Our basic concept of autocatalysis in conjunction with lateral inhibition accounts for self-regulatory biological features, including the reproducible formation of structures from near-uniform initial conditions as required by the logic of the generation cycle. Real tissue form, for instance that of budding Hydra, may often be traced back to local curvature arising within an initially relatively flat cell sheet, the position of evagination being determined by morphogenetic fields. Shell theory developed for architecture may also be applied to such biological processes. (shrink)

The introductory personal remarks refer to my motivations for choosing research projects, and for moving from physics to molecular biology and then to development, with Hydra as a model system. Historically, Trembley’s discovery of Hydra regeneration in 1744 was the begin¬ning of developmental biology as we understand it, with passionate debates about preformation versus de novo generation, mechanisms versus organisms. In fact, seemingly conflicting bottom-up and top-down concepts are both required in combination to understand development. In modern terms, this means (...) analysing the molecules involved, as well as searching for physical principles underlying development within systems of molecules, cells and tissues. During the last decade, molecular biology has provided surprising and impressive evidence that the same types of mol¬ecules and molecular systems are involved in pattern formation in a wide range of organisms, including coelenterates like Hydra, and thus appear to have been “invented” early in evolution. Likewise, the features of certain systems, especially those of developmental regulation, are found in many different organisms. This includes the generation of spatial structures by the interplay of self-enhancing activation and “lateral” inhibitory effects of wider range, which is a main topic of my essay. Hydra regeneration is a particularly clear model for the formation of defined patterns within initially near-uniform tissues. In conclusion, this essay emphasizes the analysis of development in terms of physical laws, including the application of mathematics, and insists that Hydra was, and will continue to be, a rewarding model for understanding general features of embryogenesis and regeneration. -/- -/- . (shrink)

Transactive memory theory describes the processes by which benefits for memory can occur when remembering is shared in dyads or groups. In contrast, cognitive psychology experiments demonstrate that social influences on memory disrupt and inhibit individual recall. However, most research in cognitive psychology has focused on groups of strangers recalling relatively meaningless stimuli. In the current study, we examined social influences on memory in groups with a shared history, who were recalling a range of stimuli, from word lists to personal, (...) shared memories. We focused in detail on the products and processes of remembering during in-depth interviews with 12 older married couples. These interviews consisted of three recall tasks: (1) word list recall; (2) personal list recall, where stimuli were relevant to the couples’ shared past; and (3) an open-ended autobiographical interview. We conducted these tasks individually and then collaboratively two weeks later. Across each of the tasks, although some couples demonstrated collaborative inhibition, others demonstrated collaborative facilitation. We identified a number of factors that predicted collaborative success, in particular, group-level strategy use. Our results show that collaboration may help or hinder memory, and certain interactions are more likely to produce collaborative benefits. (shrink)

This essay moves along broad lines from molecular biology to evolutionary biology and ecology to theology. Its objectives are to: 1) present some recent scientific findings in the emerging field of epigenetics that indicate that it is “the genome in context,” not genes per se, that are important in biological development and evolution; 2) show that this weakens the gene-centric neo-Darwinist explanation of evolution which, in fact, shares a certain preformationist orientation with intelligent design theory; 3) argue that the evidence (...) against a gene-centric view in no way negates Darwin’s central idea of “descent with modification”; 4) argue that an embrace of the evolutionary story, with all of its contingency and apparent lack of directionality, is not only consistent with Christianity, but actually resonates with the notion of the self-emptying love of God in Jesus Christ; and finally 5) suggest that we are called through an ecological imperative to embrace our evolutionary story, to listen to our “genetic coding,” and to reclaim our grounding as a species in the natural world. Corrigendum (published in later issue of journal): There was an error in the paragraph describing the mode of action of the small temporally-expressed RNAs (stRNAs) lin-4 and let-7 from Caenorhabditis elegans. Instead of reading "These two stRNAs act by binding to the tails of their target messenger RNAs (mRNAs); this results in destruction of the target and an overall drop in the level of production of protein from agouti mRNA" [note that agouti mRNA is not a target of these stRNAs], the sentence should have read, "These two stRNAs act by binding to the tails of target messenger RNAs (mRNAs); this leads to inhibition of translation of the mRNAs into protein and a consequent drop in the levels of the corresponding target protein.". (shrink)

When must a specific cognitive habit be called upon to solve a problem? In the subject’s learning process, “knowing-to” is connected with a conscious particular judgment of truth or “aha” moment enacting a new behavioral schema. This paper comments on recent experiments supporting the view that a shift from automatic to controlled forms of inhibition, involving conscious attention, is crucial for detecting errors and activating a new strategy in complex cognitive situations. The part that consciousness plays in this process (...) agrees with its philosophical description as “judge of truth”, and can thus be regarded as an essential precursor to the development of higher cognitive habits. In this regard, John Henry Newman’s explanation of human assent to truth, for which our consciousness of self is always prior, proves to be decisive. (shrink)

Two lines of evidence indicate that there exists a reciprocal inhibitory relationship between opposed brain networks. First, most attention-demanding cognitive tasks activate a stereotypical set of brain areas, known as the task-positive network and simultaneously deactivate a different set of brain regions, commonly referred to as the task negative or defaultmode network. Second, functional connectivity analyses show that these same opposed networks are anti-correlated in the resting state. Wehypothesize that these reciprocally inhibitory effects reflect two incompatible cognitive modes, each of (...) which may be directed towards understanding the external world. Thus, engaging onemode activates one set of regions and suppresses activity in the other.Wetest this hypothesis by identifying two types of problem-solving task which, on the basis of prior work, have been consistently associated with the task positive and task negative regions: tasks requiring social cognition, i.e., reasoning about the mental states of other persons, and tasks requiring physical cognition, i.e., reasoning about the causal/mechanical properties of inanimate objects. Social and mechanical reasoning tasks were presented to neurologically normal participants during fMRI. Each task type was presented using both text and video clips. Regardless of presentation modality, we observed clear evidence of reciprocal suppression: social tasks deactivated regions associated with mechanical reasoning and mechanical tasks deactivated regions associated with social reasoning. These findings are not explained by self-referential processes, task engagement, mental simulation,mental time travel or external vs. internal attention, all factors previously hypothesized to explain default mode network activity. Analyses of resting state data revealed a close match between the regions our tasks identified as reciprocally inhibitory and regions of maximal anti-correlation in the resting state. These results indicate the reciprocal inhibition is not attributable to constraints inherent in the tasks, but is neural in origin. Hence, there is a physiological constraint on our ability to simultaneously engage two distinct cognitive modes. Furtherwork is needed tomore precisely characterize these opposing cognitive domains. (shrink)

Entrepreneurship among youth across the world assists in job creation and self-reliance. On the same vein, there are factors that hinder their entrepreneurial intentions in establishing their goals. Compelling youth entrepreneurship development training is described by responsibility, adaptability, good local contacts and an important but intangible element of inspiration. This study investigated the on the factors inhibiting the success of entrepreneurial intentions to launch business. A case study of youth SME groups in an entrepreneurship class in United States International University (...) - Africa. The study was guided by the following objectives: to determine how propensity to risk impacts entrepreneurial intentions to launch business, to determine how locus of control impact entrepreneurial intentions to launch business, to determine how proactive personality impact entrepreneurial intentions to launch business. The study utilized descriptive survey design. (shrink)

This paper draws on work in the sciences of the mind to cast doubt on some assumptions that have often been made in the study of self-control. Contra a long, Aristotelian tradition, recent evidence suggests that highly self-controlled individuals do not have a trait very similar to continence: they experience relatively few desires that conflict with their evaluative judgments and are not especially good at directly and effortfully inhibiting such desires. Similarly, several recent studies have failed to support the view (...) that self-control capacities are constituted, at least in part, by excellent inhibitory executive function ability. I propose an alternative “indirect harmony” hypothesis about trait self-control. According to this hypothesis, if there is a character trait of being highly self-controlled, it consists in motivational harmony within the mind that is brought about through the effective use of indirect resistance strategies that prevent occurrent motivational conflict from emerging in the first place. If this hypothesis is correct, high trait self-control in actual humans does not fit neatly into the traditional categories of either continence or temperance. I conclude by drawing out several implications this hypothesis has for future research on trait self-control and its relation to executive functions. (shrink)

Abstract: In this research, an Artificial Neural Network (ANN) model was developed and tested to predict effect of oxygen consumption of thylakoid membranes (chloroplasts) from spinach after inhibition. A number of factors were identified that may affect of oxygen consumption of thylakoid membranes from spinach. Factors such as curve, herbicide, dose, among others, as input variables for the ANN model. A model based on multi-layer concept topology was developed and trained using the data from some inhibition of photosynthesis (...) in farms. The evaluation of testing the dataset shows that the ANN model is capable of correctly predicting the effect of oxygen consumption of thylakoid membranes (chloroplasts) from spinach after inhibition with 100% accuracy. (shrink)

Religious tourism is as old as religion itself and consequently, it is the oldest form of tourism in the world. Most religions have holy places that people visit from time to time for several reasons. This work examines the Ababa carnival which involves faith- activities, but in a heightened form. It involves pilgrimages to the Ababa holy shrine in Esin Ufot Eyo-Abasi in Oron. This work identifies as a problem, the lack of basic infrastructures and non-patriotic and neglecting attitudes of (...) Nigerians towards their indigenous religious tourism development, as they are so much involved in faith-based activities and travels to Israel, Mecca, Rome among several others. It adopts the Phenomenological method in a Culture Area of Oron. As primary research, it will rely on oral interviews and secondary materials from the libraries and the internet. The findings indicate that the positive effects of indigenous faith-based religious tourism such as Ababa are yet to be used in developing Oron and Nigeria as found in other parts of the world such as Israel, Saudi Arabia, and Italy. This work concludes that traditional religious tourism can be used as a tool for National Development and unity of Nigeria. As a recommendation it calls on the government who sponsors individuals and particular religious groups on pilgrimages, to divert such funds and invest in infrastructural development in Oron to attract tourists to the area and as well develop traditional religious tourism of Nigeria, as this will reduce poverty and create employment opportunities. (shrink)

How surprising is the insight, that being equals I in the 15th lecture of the Doctrine of Science 1804/II? It might have been indeed an unexpected turn for his contemporaries in Berlin listening to Fichte for the first time, but should it be surprising for us, having at least since 2012 (the year the last volume of [Gesamtausgabe] appeared) access to all his published and unpublished works? I want to propose a way of reading Fichte, which bypasses two popular and (...) contradictory interpretations of his philosophy in the post-Jena period: (a) the Absolute is the new first principle (hence the I is just a shadow of the much higher being) and (b) his system basically remains unchanged (hence the being is nothing more than the I). At first, I analyze the functions of later Fichte’s improved version of the Kantian and Reinholdian abstract subject-object-symbolism and assign specific content to it. This will shed light on the structure and the first principle of the Doctrine of Science 1804/II. In the second section I give reasons why Fichte calls both God and I “absolute” and “pure being” and explain their relation to each other referring to a thought experiment sometimes used by Kant—an analogy between the divine and human (pure) reason. The analogical thinking of this kind remains within the borders of transcendental philosophy as long as it is used only for certain didactic purposes. (shrink)

Our approach is based on a tri-partite method of integrating psychodynamic hypotheses, cognitive subliminal processes, and psychophysiological alpha power measures. We present ten social phobic subjects with three individually selected groups of words representing unconscious conflict, conscious symptom experience, and Osgood Semantic negative valence words used as a control word group. The unconscious conflict and conscious symptom words, presented subliminally and supraliminally, act as primes preceding the conscious symptom and control words presented as supraliminal targets. With alpha power as a (...) marker of inhibitory brain activity, we show that unconscious conflict primes, only when presented subliminally, have a unique inhibitory effect on conscious symptom targets. This effect is absent when the unconscious conflict primes are presented supraliminally, or when the target is the control words. Unconscious conflict prime effects were found to correlate with a measure of repressiveness in a similar previous study (Shevrin et al., 1992, 1996). Conscious symptom primes have no inhibitory effect when presented subliminally. Inhibitory effects with conscious symptom primes are present, but only when the primes are supraliminal, and they did not correlate with repressiveness in a previous study (Shevrin et al., 1992, 1996). We conclude that while the inhibition following supraliminal conscious symptom primes is due to conscious threat bias, the inhibition following subliminal unconscious conflict primes provides a neurological blueprint for dynamic repression: it is only activated subliminally by an individual's unconscious conflict and has an inhibitory effect specific only to the conscious symptom. These novel findings constitute neuroscientific evidence for the psychoanalytic concepts of unconscious conflict and repression, while extending neuroscience theory and methods into the realm of personal, psychological meaning. (shrink)

I show that Wittgenstein's critique of G.H. Hardy's mathematical realism naturally extends to Paul Benacerraf's influential paper, ‘Mathematical Truth’. Wittgenstein accuses Hardy of hastily analogizing mathematical and empirical propositions, thus leading to a picture of mathematical reality that is somehow akin to empirical reality despite the many puzzles this creates. Since Benacerraf relies on that very same analogy to raise problems about mathematical ‘truth’ and the alleged ‘reality’ to which it corresponds, his major argument falls prey to the same critique. (...) The problematic pictures of mathematical reality suggested by Hardy and Benacerraf can be avoided, according to Wittgenstein, by disrupting the analogy that gives rise to them. I show why Tarskian updates to our conception of ‘truth’ discussed by Benacerraf do not answer Wittgenstein's concerns. That is, because they merely presuppose what Wittgenstein puts into question, namely, the essential uniformity of ‘truth’ and ‘proposition’ in ordinary discourse. (shrink)

We argue the thesis that if (1) a physical process is mathematically representable by a Cauchy sequence; and (2) we accept that there can be no infinite processes, i.e., nothing corresponding to infinite sequences, in natural phenomena; then (a) in the absence of an extraneous, evidence-based, proof of `closure' which determines the behaviour of the physical process in the limit as corresponding to a `Cauchy' limit; (b) the physical process must tend to a discontinuity (singularity) which has not been reflected (...) in the Cauchy sequence that seeks to describe the behaviour of the physical process. We support our thesis by mathematical models of the putative behaviours of (i) a virus cluster; (ii) an elastic string; and (iii) a Universe that recycles from Big Bang to Ultimate Implosion, in which parity and local time reversal violation, and the existence of `dark energy' in a multiverse, need not violate Einstein's equations and quantum theory. We suggest that the barriers to modelling such processes in a mathematical language that seeks unambiguous communication are illusory; they merely reflect an attempt to ask of the language chosen for such representation more than it is designed to deliver. (shrink)

The Turing Test is one of the most disputed topics in artificial intelligence, philosophy of mind, and cognitive science. This paper is a review of the past 50 years of the Turing Test. Philosophical debates, practical developments and repercussions in related disciplines are all covered. We discuss Turing's ideas in detail and present the important comments that have been made on them. Within this context, behaviorism, consciousness, the 'other minds' problem, and similar topics in philosophy of mind are discussed. We (...) also cover the sociological and psychological aspects of the Turing Test. Finally, we look at the current situation and analyze programs that have been developed with the aim of passing the Turing Test. We conclude that the Turing Test has been, and will continue to be, an influential and controversial topic. -/- (This paper was reprinted in: The Turing Test: The Elusive Standard of Artificial Intelligence, J. H. Moor, ed., Kluwer Academic, pp. 23-78, 2003.). (shrink)

This dissertation is a discussion of Wittgenstein's later philosophy. In it, Wittgenstein's answer to the "going on problem" will be presented: I will give his reply to the skeptic who denies that rule-following is possible. Chapter One will describe this problem. Chapter Two will give Wittgenstein's answer to it. Chapter Three will show how Wittgenstein used this answer to give the standards of mathematics. Chapter Four will compare Wittgenstein's answer to the going on problem to Plato's. Chapter Five will describe (...) Kant's influence on Wittgenstein's later philosophy. The leitmotif of these chapters will be that the way human beings apply a rule is the source of justification for its application. 1. (shrink)

This dissertation is a discussion of Wittgenstein's later philosophy. In it, Wittgenstein's answer to the "going on problem" will be presented: I will give his reply to the skeptic who denies that rule-following is possible. Chapter One will describe this problem. Chapter Two will give Wittgenstein's answer to it. Chapter Three will show how Wittgenstein used this answer to give the standards of mathematics. Chapter Four will compare Wittgenstein's answer to the going on problem to Plato's. Chapter Five will describe (...) Kant's influence on Wittgenstein's later philosophy. The leitmotif of these chapters will be that the way human beings typically apply a rule is the source of justification for an individual's usage thereof. (shrink)

In this article I claim that distinction should be made between an "early Derrida" and a "later Derrida," similar to the one made between Wittgenstein of the Tractatus and Wittgenstein of the Investigations, or between Heidegger before the Kehre and Heidegger after it. Acceptance of such a distinction enables us to understand Derrida's teachings more clearly, to solve a disagreement in Derrida scholarship, and to understand his deconstruction as less contradictory. I shall also explain the reasons for, and causes of, (...) the change in Derrida' teachings and distinguish between those aspects that changed and those that did not. (shrink)

According to an influential reading of his later philosophy, Wittgenstein thinks that nonsense can result from combining expressions in ways prohibited by the rules to which their use is subject. According to another influential reading, the later Wittgenstein thinks that nonsense only ever results from privation—that is, from a failure to assign a meaning to one or more of the relevant expressions. This chapter challenges Glock’s defence of the view that the later Wittgenstein allows for combinatorial nonsense. In doing so, (...) it defends a version of the privation view. According to it, Wittgenstein thinks that nonsense results, not so much from a failure to assign a meaning to an expression, as a failure to use an expression in a way that has a point or purpose. As the chapter shows, this interpretation is consistent with prominent themes in Wittgenstein’s later philosophy, such as that meaning and explanation are coordinate notions, that for a word to have a meaning is for there to be a rule-governed practice of using it, that the rules of the practice are arbitrary, and that they determine the bounds of sense. (shrink)

This essay reconsiders David Hume’s thinking on the fate of the British Empire and the future of established religion. It provides a detailed reconstruction of the development of Hume’s views on Britain’s successive attempts to impose or regain its authority over its North American colonies and compares these views with the stance taken during the American Crisis by Adam Smith and Josiah Tucker. Fresh light is shed on this area of Hume’s later political thought by a new letter, appended to (...) the essay, which at the same time provides an illuminating glimpse of his abiding preoccupation with the future of established religion. It is argued that this evidence of Hume’s privately held views belies the notion that his thinking on political and religious matters was fundamentally opposed to that of his friends among the philosophes. It is consequently misleading to regard Hume as an opponent of the more radical wing of the Enlightenment. (shrink)

In this paper, I shall review the reasons that let Putnam to propose functionalism and the reasons that subsequently led him to abandon it. I would like to discuss Putnam's views belonging to early Putnam and later Putnam. First, let us focus on early Putnam. Early Putnam tries to show the possibility of robot consciousness. As a functionalist, Putnam shows that the human being is an autonomous: that is, human mind is a computing machine. Later, he changes his position to (...) demonstrate not just his intellectual confidence, but also the virtue of seeing the bigger picture. Later Putnam realized this because this sort of utopianism is an illustration of what is called ‘scientism’. It is based on speculations regarding scientific possibilities. The problem is that it is completely unclear just what possibility has been envisaged when one speaks of robotic consciousness. While arguing against Turing machine, the later Putnam said that pessimism about the success of artificial intelligence (AI) in simulating human intelligence amounts to pessimism about possibility of describing the functioning of the brain. He raised the question: what connection is there between simulating intelligence and describing the brain? Even if the computer model of the brain is correct, it does not follow that AI will succeed. Simulation is just simulation, it does not mean exact replications of human mind. (shrink)

Two meta-analyses of 66 behavioral studies examined variables influencing functional cerebral lateralization of each language of brain-intact bilingual adults. Functional lateralization was found to be primarily influenced by age of onset of bilingualism: bilinguals who acquired both languages by 6 years of age showed bilateral hemispheric involvement for both languages, whereas those who acquired their second language after age 6 showed left hemisphere dominance for both languages. Moreover, among late bilinguals, left hemisphere involvement was found to be greater for those (...) less proficient in their second language, those whose second language was English, and for studies involving dichotic listening paradigms; early bilinguals instead showed bilateral involvement in every condition. Implications of the observed differences in lateralization between early and late bilinguals are explored for existing theories of bilingualism and for neurocognitive models of brain functional organization of language. (shrink)

The aim of this paper is to read Martin Heidegger’s later philosophy in terms of the assertion that themes such as the fourfold (das Geviert) and poetic dwelling could be interpreted as mythical elements within his writing. Heidegger’s later thought is often construed as challenging and difficult due to its quasi-mystical nature. However, this paper aims to illustrate that if one approaches his later thought from the perspective of myth, a different dimension of Heidegger’s thinking is revealed which is perhaps (...) more tenable than attempting to address his later thought purely from a philosophical position. In brief, Heidegger’s concept of the fourfold involves the following entities: mortals, divinities, the sky and the earth. His argument is that for mortals to dwell poetically (implying the living of a meaningful, holistic life) they must recognise and assume the guardianship of Being (which is inclusive of all the elements of the fourfold). Heidegger argues that our guardianship of Being will be a natural extension of our existence, once we realise the holiness or sacred nature of Being as such. Thus, the concept of the fourfold represents the possibility of existing in a harmonious, caring (or saving), relationship with Being. However, following Heidegger this holistic (and, arguably mythical) depiction of our existence is extremely unlikely due to the rampant nature of technological enframing (Gestell) that dictates the use of human and natural resources. Conceptually though, if this holistic depiction is approached taking into account Ricoeur’s argument regarding myth then it becomes tenable. Ricoeur writes that myth has a symbolic function in terms of its power of discovery and revelation and this implies that myth has a projected horizon. This horizon, Ricoeur writes, is a ‘disclosure of unprecedented worlds, an opening on to other possible worlds which transcend the established limits of our actual world’ (1997: 8). Thus, applying these characterisations of myth to elements of Heidegger’s later philosophy will reveal a justifiable and coherent interpretation of his concept of the fourfold from a mythical perspective. Such a reading demonstrates the centrality of the fourfold in Heidegger’s later thought, which more strictly philosophical approaches may undervalue. In closing this paper suggests the usefulness of a mythological approach to the later Heidegger, and demonstrates the continued vitality of myth, as a profoundly human paradigm which, as Heidegger recognised, can simultaneously complement and transcend our more restricted rational endeavours. (shrink)

A discussion of how diggers stance with regard to contemporary analytic and Continental philosophy, with special emphasis on Heidegger's later works. The essay argues that Heidegger has now become attacks that people can interpret in many ways, and so is entered into dialogues which go against his own self-image of what he was about.

In this essay I take up the later major anti-Semitic propaganda pieces, all of them released in 1940. They were produced under Goebbels explicit orders to each of the three Nazi-controlled studios to produce an anti-Semitic film. The three films produced were: The Rothschilds Share at Waterloo; Jud Suss; and The Eternal Jew. These films were much more powerful propaganda pieces in intensifying anti-Semitic feelings—those feelings of difference, disgust, and danger. For each film, I point to the scenes that arouse (...) the feelings even more profoundly than did the earlier films. The Rothschilds’ Shares at Waterloo put forward the conspiracy theory (widespread to this day) that Jewish bankers form a conspiratorial cabal bent upon world domination. Jew Suss (which was presented as historically true) pushes the narrative of Jews using money to take power, and of their boundless lust for young Christian women (hence the danger of “racial pollution”). Of all the anti-Semitic propaganda films the regime produced, the top regime figures considered this to be the most powerful—about 40% of German adults of the time saw this film. It is banned in Germany to this day. Finally, The Eternal Jew—perhaps the most infamous of the group—is presented as a truthful documentary. While this sham documentary was a comparative box office flop, it was widely used as a training film. (shrink)

Leave logic at the door and prepare to test your creative thinking skills with these 100 brand new lateral thinking puzzles. Each puzzle describes a situation which at first sounds odd or unlikely, and you have to work your way to the answer using creativity, imagination, and intuition. To cater for all ability levels, the 100 puzzles are arranged into Easy, Moderate, and Difficult categories, and a series of hints is provided for each puzzle to help you along if (...) you get stuck. As lateral thinking puzzles are fun, engaging, and make good icebreakers, they are a perennial favourite at dinner parties, break times, and social evenings. (shrink)

The present volume brings together work that will be of interest both to specialists in medieval philosophy and to those working in contemporary or more recent historical periods of metaphysics. Th...

We have witnessed the athleticization of political discourse, whereby debate is treated like an athletic contest in which the aim is to vanquish one's opponents. When political discourse becomes a zero-sum game, it is characterized by suspicions, accusations, belief polarization, and ideological entrenchment. Unfortunately, athleticization is ailing the classroom as well, making it difficult for educators to prepare students to make valuable contributions to healthy civic discourse. Such preparation requires an educational environment that fosters the intellectual virtues that characterize an (...) examined life. This, in turn, requires an amicable and hospitable atmosphere in which a student enjoys the freedom to discover and articulate what she believes, how well her beliefs hang together, and what underlying assumptions or biases might be at work—without the fear that her self-disclosure will trigger immediate accusations and pigeonholing from fellow students. Educating for intellectual virtue is crucial for meeting these challenges and in this chapter we contribute to this strategy by offering some tools and guidance for promoting productive discussion of controversial issues. In the first two sections, we identify and explain two fallacious patterns of thought that often encumber discussion of controversial issues: assailment-by-entailment and the attitude-to-agent fallacy. In effect, these sections diagnose two diseases of discourse. We conclude each section with practical suggestions—in the form of thinking routines—for curing these ills. We will argue that part of the cure is to be found in the intellectual virtues. In particular, we will discuss how the virtues of intellectual charity, humility and carefulness can inoculate the mind against the fallacies we identify. (shrink)

Within the context of Heidegger’s claim that his thinking has moved from the “meaning of being” to the “truth of being” and finally to the “place of being,” this paper examines the “spatial” motifs that become pronounced in his post-1930 attempts to think being apart from temporality. My contention is that his “shift” (Wendung) in thinking was a move beyond his earlier focus upon the project-horizon of the meaning (Sinn) of being, i.e., time, based on the existential hermeneutic of mortality, (...) and instead towards a focus upon the “space”—variously discussed in terms of the open, the clearing, the expanse, the region, etc.—that allows fur such horizonal projection. The very matter of thought that becomes discussed in the 1930s Beiträge as the “turning” (Kehre) of “en-ownment” (Ereignis) involves this clearing or opening of a “space” in the strife of unconcealment-concealment. This in turn underscores the alterity from out of which the emission of the Sinn of being is possible. In the 1940s and ‘50s this spacing becomes developed in terms of a “regionalizing” (Gegnen) in explicit distinction from the “horizon.” I shall also examine the implications for human spatiality, i.e., our receptivity vis-à-vis this alterity of Ereignis or Gegnen, which Heidegger discusses in terms of “letting” or “releasement.”. (shrink)

This chapter examines Wittgenstein’s battles with the profound anxiety that can arise in response to a sense of the radical contingency of everything one is and everything one cares about. By giving particular attention to entries in Wittgenstein’s ‘Koder Diaries’ from the 1930s, the chapter analyses the nature of ‘the problem of life’ both as it manifested in Wittgenstein’s own life and as a universally relevant problem. It then defends the seriousness of the problem by reconstructing ways in which Wittgenstein (...) might have responded to questions about whether life really is as problematically precarious as his most angst-ridden diary entries seem to presume. (Abstract adapted from Mikel Burley’s ‘Introduction: Wittgenstein, Religion and Ethics: Seeing the Connections’, p. 7). (shrink)

Most abortions occur early in pregnancy. I argue that these abortions, and so most abortions, are not morally wrong and that the best arguments given to think that these abortions are wrong are weak. I also argue that these abortions, and probably all abortions, should be legal. -/- I begin by observing that people sometimes respond to the issue by describing the circumstances of abortion, not offering reasons for their views about those circumstances; I then dismiss “question-begging” arguments about abortion (...) that merely assume the conclusions they are given to support; most importantly, I evaluate many arguments: both common, often-heard arguments and arguments developed by philosophers. -/- My defense of abortion is based on facts about early fetuses’ not yet possessing consciousness or any mental life, awareness or feeling, as well as concerns about rights to one’s own body. (shrink)

What qualities do we need in order to be good philosophers? Wittgenstein insists that virtues of character – such as honesty, humility, courage, and strength – are more important for our philosophizing than the relevant intellectual talents and skills. These virtues are essential because doing good philosophy demands both knowing and overcoming the deep-seated desires and inclinations which lead us astray in our thinking, and achieving such self-knowledge and self-overcoming demands all of these virtues working in concert. In this paper (...) I draw together many of Wittgenstein’s seemingly offhanded remarks on these issues in order to reconstruct his understanding of philosophy’s ‘difficulties of the will’ and the virtues needed to overcome them. (shrink)

This chapter discusses three types of sociable robots for older adults: robotic caregivers ; robotic friends ; and sex robots. The central argument holds that society ought to make reasonable efforts to provide these types of robots and that under certain conditions, omitting such support not only harms older adults but poses threats to their dignity. The argument proceeds stepwise. First, the chapter establishes that assisting care-dependent older adults to perform activities of daily living is integral to respecting dignity. Here, (...) the argument establishes the vital role that carebots-of-the-future might play in aged societies as the supply of working age adults falls shy of demand. Next, the chapter extends this analysis to designing friendbots for socially isolated older adults. The argument holds that reasonable efforts to provide access to friendbots for socially isolated adults is also a future societal responsibility. Finally, the chapter applies similar reasoning to show that societies ought to make reasonable efforts to support sexual capabilities for older adults who want to be sexual but are bereft of sex partners. The argument draws on capability accounts of justice to show that when central human capacities, such as bodily integrity; intimate relationships; and the use of senses, imagination and thought, are at risk of falling below a threshold level, society should intercede. (shrink)

Background: Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease, associated with a reciprocal translocation between chromosomes 9 and chromosome 22, lead to the formation of the BCRABL fusion gene (Philadelphia chromosome). This fusion gene is believed to play golden role in the initial development of CML with constitutive tyrosine kinase activation. Successful use of tyrosine kinase inhibiters (TKIs) play a role in improve survival and increase prevalence of CML, but un fortunately mutations in the BCR-ABL kinase domain may (...) cause, or contribute to increase, resistance to TKIs in CML patients. . Objective: This study was designed to assess the association of five most common BCR-ABL kinase domain mutations (T315I, M351T, E255K, M244V and E255V) with resistance state of CML patients on TKIs in Iraqi Middle Euphrates region. Patients and methods: A retrospective case-control study in which 85 patients with chronic myeloid leukemia in chronic phase (45 patients as cases group and 40 patient as control group) were selected from three hemato-oncology centers in middle Euphrates in Iraq during the period from January 2016 till October 2016 out of a total of 240 CML patients (108 male and 132 female) who were registered during this period in these three centers and all patients on TKI (Imatinib and Nilotinib). Venous blood sampling done for BCRABL kinase domain mutations screening. Results: four patients from cases group (4/45) were carriers of one of five selected ABL kinase domain mutations and no one of control group. T315I mutation was detected in 3/45 (6.6 %) of resistant patients, with a significant risk association to develop resistance to TKI therapy (odd ratio and C. I.) (6.67, 0.3340 - 133.2255). E255V was detected in 1/45 (2.2 %) and also had significant risk association to develop resistance to TKIs (odd ratio, C.I.) (2.73, 0.1081 -68.9424). No one of these mutations had significance correlation with demographic or hematological features. M351T, E255K and M244V were not detected in any one of our study groups CML patients. Conclusions: T315I and E255V among five ABL kinas domain mutations were detected in our CML patients with resistance to TKIs. All of them may play a role in development variable degree of resistance to first and second generation TKIs weather primary or secondary.T315I mutation is most common mutation within BCR-ABL domain kinase gene. (shrink)

I highlight three features of P.F. Strawson’s later, neglected work on freedom and responsibility. First, in response to a criticism by Rajendra Prasad, Strawson explicitly rejects an argument put forward in ‘Freedom and Resentment’ against the relevance of determinism to moral responsibility. Second, his remarkable acceptance of Prasad’s criticism motivates him to take the ‘straight path’, that is, to be straightforward about the relation between determinism, freedom, the ability to do otherwise and the conditions of responsibility. He claims that the (...) ability to do otherwise is a necessary condition of responsibility and provides a list of additional conditions, including a knowledge condition. Third, he clarifies the relation between responsibility, quality of will and the reactive attitudes. The latter do not figure essentially in his answer to the question, ‘What are the conditions of responsibility?’, but they do play an essential role in his answer to the question, ‘Why do we have the concept of responsibility?’ We have it, Strawson suggests, because of our natural concern about the quality of will with which people act, a concern expressed in our reactive attitudes. I argue that, although Strawson’s later work definitely involves a shift of emphasis when compared to ‘Freedom and Resentment’, his overall account of freedom and responsibility is coherent. The later work helps to better understand the nature and significance of Strawson’s contribution, and to identify problems with common interpretations of and objections to ‘Freedom and Resentment’. (shrink)

The point of Wittgenstein’s remarks on colour concerns, not so much colours as such, as well as our ability to see [that implies both seeing ánd thinking] and our capacity to imagine something. This can be seen from the fact that Wittgenstein relates the notion of ‘seeing aspects’ on the one hand to the colour octahedron in PB, and on the other hand to the colour puzzles as discussed in ROC. This connection between Wittgenstein’s remarks on colour, on seeing aspects (...) and on certainty makes clear that these investigations of Wittgenstein direct us towards a reflective dynamics of his ideas. (shrink)

This dissertation provides a careful reading of the later Wittgenstein’s philosophy of mathematics centered around three major themes: reality, determination, and infinity. The reading offered gives pride of place to Wittgenstein’s therapeutic conception of philosophy. This conception views questions often taken as fundamental in the philosophy of mathematics with suspicion and attempts to diagnose the confusions which lead to them. In the first essay, I explain Wittgenstein’s approach to perennial issues regarding the alleged reality to which mathematical truths or propositions (...) correspond. Wittgenstein diagnoses exotic pictures of mathematical reality as stemming from misleading analogies formed across empirical and mathematical propositions. The second essay explains Wittgenstein’s treatment of perplexity regarding the ability of a mathematical rule to determine its applications in advance. This too is found to depend on a misleading analogy, in this case across behavioral and mathematical senses of ‘determine’. The third and final essay discusses Wittgenstein’s general critical approach to “the infinite”. Philosophical perplexity about infinity is shown to depend on the verbal imagery regularly associated with proofs and their power to take hold of one’s imagination. Wittgenstein dampens the imaginative excesses often associated with “the infinite” by offering a sober redescription of Cantor’s famous method of diagonalization. (shrink)

The issue of whether or not there are visual arguments has been an issue in informal logic and argumentation theory at least since 1996. In recent years, books, sections of prominent conferences and special journals issues have been devoted to it, thus significantly raising the profile of the debate. In this paper I will attempt to show how the views of the later Wittgenstein, particularly his views on images and the no- tion of “picturing”, can be brought to bear on (...) the question of whether there are such things as “purely visual” arguments. I shall draw on Wittgenstein’s remarks in the Blue and Brown Books and in Philosophical Investigations in order to argue that al- though visual images may occur as elements of argumentation, broadly conceived, it is a mistake to think that there are purely visual arguments, in the sense of illative moves from premises to conclusions that are conveyed by images alone, without the support or framing of words. (shrink)

In this essay I argue the extent to which meaning and judgment in aesthetics figures in Wittgenstein’s later conception of language, particularly in his conception of how philosophy might go about explaining the ordinary functioning of language. Following a review of some biographical and textual matters concerning Wittgenstein’s life with music, I outline the connection among (1) Wittgenstein’s discussions of philosophical clarity or perspicuity, (2) our attempts to give clarity to our aesthetic experiences by wording them, and (3) the clarifying (...) experience of the dawning of an aspect, which Wittgenstein pictures as the perception of an internal relation. By examining Wittgenstein’s use of “internal relation” from the Tractatus to his later writings, I come to challenge the still prevalent understanding of Wittgenstein’s appeals to grammar as an appeal to something given (e.g., to a set of grammatical rules). Instead, as I argue, Wittgensteinian appeals to grammatical criteria should be understood as modeled by the form of justification found in our conversations about art. (shrink)

This article is a response to the paradoxical nature of Moore's views on sense perception. By arguing that Moore's later stance on the objective world (that there are both mind-dependent and mind-independent features) requires a causal theory of perception, this article suggests that Moore lacks the epistemic justification needed to make assertions about the nature of mind-independent matter. Instead, the idealistic reply proposed in this article is to first dissolve Moore's distinction between mind-dependent and mind-independent features of the world, and (...) to then argue that shape, colour and other such qualities are known only in virtue of their similar perceptual (mind-dependent) origins. This article further diverges from Moore by concluding that objects are not mind-independent at all, but always indebted to various acts of cognitive construction. (shrink)

This paper proposes a new reading of the interaction between subjectivity, reflection and freedom within Foucault’s later work. I begin by introducing three approaches to subjectivity, locating these in relation both to Foucault’s texts and to the recent literature. I suggest that Foucault himself operates within what I call the ‘entanglement approach’, and, as such, he faces a potentially serious challenge, a challenge forcefully articulated by Han. Using Kant’s treatment of reflection as a point of comparison, I argue that Foucault (...) possesses the resources to meet this challenge. The key, I contend, is to distinguish two related theses about reflection and freedom: Foucault’s position is distinctive precisely because he accepts one of these theses whilst rejecting the other. I conclude by indicating how this reading might connect to the longstanding question of Foucault’s own right to appeal to normative standards. (shrink)