Editorial preface to the fourth edition and modified translation -- The text of the Philosophische Untersuchungen -- Philosophische untersuchungen = Philosophical investigations -- Philosophie der psychologie, ein fragment = Philosophy of psychology, a fragment.

Thomas S. Kuhn's classic book is now available with a new index.

In this powerful work of conceptual and analytical originality, the author argues for the primacy of the material arrangements of the laboratory in the dynamics of modern molecular biology. In a post-Kuhnian move away from the hegemony of theory, he develops a new epistemology of experimentation in which research is treated as a process for producing epistemic things. A central concern of the book is the basic question of how novelty is generated in the empirical sciences. In addressing this question, (...) the author brings French poststructuralist thinking—notably Jacques Derrida’s concepts of “différance” and “historiality”—to bear on the construction of epistemic things. Historiographical perspective shifts from the actors’ minds to their objects of manipulation. These epistemological and historical issues are illuminated in a detailed case study of a particular laboratory, that of the oncologist and biochemist Paul C. Zamecnik and his colleagues, located in a specific setting—the Collis P. Huntington Memorial Hospital of Harvard University at the Massachusetts General Hospital of Boston. The author traces how, between 1945 and 1965, this group developed an experimental system for synthesizing proteins in the test tube that put Zamecnik’s research team at the forefront of those who led biochemistry into the era of molecular biology. (shrink)

Although science was once seen as the product of individual great men working in isolation, we now realize that, like any other creative activity, science is a highly social enterprise, influenced in subtle as well as obvious ways by the wider culture and values of its time. Scientific Knowledge is the first introduction to social studies of scientific knowledge. The authors, all noted for their contributions to science studies, have organized this book so that each chapter examines a key step (...) in the process of doing science. Using case studies from cognitive science, physics, and biology to illustrate their descriptions and applications of the social study of science, they show how this approach provides a crucial perspective on how science is actually done. Scientific Knowledge will be of interest not only to those engaged in science studies, but also to anyone interested in the practice of science. (shrink)