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How do medical researchers make causal inferences?

In Kevin McCain & Kostas Kampourakis (eds.), What is scientific knowledge? An introduction to contemporary epistemology of science. London, UK: Routledge (2020)

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  1. Abductive inference: computation, philosophy, technology.John R. Josephson & Susan G. Josephson (eds.) - 1994 - New York: Cambridge University Press.
    In informal terms, abductive reasoning involves inferring the best or most plausible explanation from a given set of facts or data. It is a common occurrence in everyday life and crops up in such diverse places as medical diagnosis, scientific theory formation, accident investigation, language understanding, and jury deliberation. In recent years, it has become a popular and fruitful topic in artificial intelligence research. This volume breaks new ground in the scientific, philosophical, and technological study of abduction. It presents new (...)
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  • Copernicus, Ptolemy, and explanatory coherence.G. Nowak & P. Thagard - 1992 - In Ronald N. Giere (ed.), Cognitive Models of Science. pp. pp. 274-309.
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  • Copernicus, Ptolemy, and explanatory coherence.Greg Nowak & Paul Thagard - 1992 - In Ronald N. Giere (ed.), Cognitive Models of Science. pp. 274-309.
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  • The origin of species.Charles Darwin - 1859 - New York: Norton. Edited by Philip Appleman.
    In The Origin of Species (1859) Darwin challenged many of the most deeply-held beliefs of the Western world. Arguing for a material, not divine, origin of species, he showed that new species are achieved by "natural selection." The Origin communicates the enthusiasm of original thinking in an open, descriptive style, and Darwin's emphasis on the value of diversity speaks more strongly now than ever. As well as a stimulating introduction and detailed notes, this edition offers a register of the many (...)
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  • Thought.Gilbert Harman & Laurence BonJour - 1975 - Philosophical Review 84 (2):256.
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  • Concepts as Semantic Pointers: A Framework and Computational Model.Peter Blouw, Eugene Solodkin, Paul Thagard & Chris Eliasmith - 2016 - Cognitive Science 40 (5):1128-1162.
    The reconciliation of theories of concepts based on prototypes, exemplars, and theory-like structures is a longstanding problem in cognitive science. In response to this problem, researchers have recently tended to adopt either hybrid theories that combine various kinds of representational structure, or eliminative theories that replace concepts with a more finely grained taxonomy of mental representations. In this paper, we describe an alternative approach involving a single class of mental representations called “semantic pointers.” Semantic pointers are symbol-like representations that result (...)
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  • Falsificationism and the Methodology of Scientific Research Programs' in I. Lakatos and A. Musgrave.Imre Lakatos - 1970 - In Imre Lakatos & Alan Musgrave (eds.), Criticism and the growth of knowledge. Cambridge [Eng.]: Cambridge University Press.
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  • The Structure of Scientific Revolutions.Thomas Samuel Kuhn - 1962 - Chicago: University of Chicago Press. Edited by Otto Neurath.
    A scientific community cannot practice its trade without some set of received beliefs. These beliefs form the foundation of the "educational initiation that prepares and licenses the student for professional practice". The nature of the "rigorous and rigid" preparation helps ensure that the received beliefs are firmly fixed in the student's mind. Scientists take great pains to defend the assumption that scientists know what the world is like...To this end, "normal science" will often suppress novelties which undermine its foundations. Research (...)
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  • The Structure of Scientific Revolutions.Thomas S. Kuhn - 1962 - Chicago, IL: University of Chicago Press. Edited by Ian Hacking.
    Thomas S. Kuhn's classic book is now available with a new index.
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  • Natural Philosophy: From Social Brains to Knowledge, Reality, Morality, and Beauty.Paul Thagard - 2019 - New York: Oup Usa.
    Paul Thagard uses new accounts of brain mechanisms and social interactions to forge theories of mind, knowledge, reality, morality, justice, meaning, and the arts. Natural Philosophy brings new methods for analyzing concepts, understanding values, and achieving coherence. It shows how to unify the humanities with the cognitive and social sciences.
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  • Ulcers and bacteria I: discovery and acceptance.Paul Thagard - 1998 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 29 (1):107-136.
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  • Ulcers and bacteria I: discovery and acceptance.Paul Thagard - 1998 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 29 (1):107-136.
    In 1983, Dr. J. Robin Warren and Dr. Barry Marshall reported finding a new kind of bacteria in the stomachs of people with gastritis. Warren and Marshall were soon led to the hypothesis that peptic ulcers are generally caused, not by excess acidity or stress, but by a bacterial infection. Initially, this hypothesis was viewed as preposterous, and it is still somewhat controversial. In 1994, however, a U. S. National Institutes of Health Consensus Development Panel concluded that infection appears to (...)
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  • The best explanation: Criteria for theory choice.Paul R. Thagard - 1978 - Journal of Philosophy 75 (2):76-92.
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  • Explanatory coherence (plus commentary).Paul Thagard - 1989 - Behavioral and Brain Sciences 12 (3):435-467.
    This target article presents a new computational theory of explanatory coherence that applies to the acceptance and rejection of scientific hypotheses as well as to reasoning in everyday life, The theory consists of seven principles that establish relations of local coherence between a hypothesis and other propositions. A hypothesis coheres with propositions that it explains, or that explain it, or that participate with it in explaining other propositions, or that offer analogous explanations. Propositions are incoherent with each other if they (...)
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  • Givenness and explanatory coherence.Wilfrid Sellars - 1973 - Journal of Philosophy 70 (October):612-624.
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  • The Structure of Scientific Revolutions.David Bohm - 1964 - Philosophical Quarterly 14 (57):377-379.
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  • Thought.Gilbert Harman - 1973 - Princeton, NJ, USA: Princeton University Press.
    Thoughts and other mental states are defined by their role in a functional system. Since it is easier to determine when we have knowledge than when reasoning has occurred, Gilbert Harman attempts to answer the latter question by seeing what assumptions about reasoning would best account for when we have knowledge and when not. He describes induction as inference to the best explanation, or more precisely as a modification of beliefs that seeks to minimize change and maximize explanatory coherence. Originally (...)
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  • Waves, particles, and explanatory coherence.Chris Eliasmith & Paul Thagard - 1997 - British Journal for the Philosophy of Science 48 (1):1-19.
    Peter Achinstein (1990, 1991) analyses the scientific debate that took place in the eighteenth and nineteenth centuries concerning the nature of light. He offers a probabilistic account of the methods employed by both particle theorists and wave theorists, and rejects any analysis of this debate in terms of coherence. He characterizes coherence through reference to William Whewell's writings concerning how "consilience of inductions" establishes an acceptable theory (Whewell, 1847) . Achinstein rejects this analysis because of its vagueness and lack of (...)
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  • Integrating structure and meaning: a distributed model of analogical mapping.Chris Eliasmith & Paul Thagard - 2001 - Cognitive Science 25 (2):245-286.
    In this paper we present Drama, a distributed model of analogical mapping that integrates semantic and structural constraints on constructing analogies. Specifically, Drama uses holographic reduced representations (Plate, 1994), a distributed representation scheme, to model the effects of structure and meaning on human performance of analogical mapping. Drama is compared to three symbolic models of analogy (SME, Copycat, and ACME) and one partially distributed model (LISA). We describe Drama's performance on a number of example analogies and assess the model in (...)
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  • Mental Mechanisms: Philosophical Perspectives on Cognitive Neuroscience.William Bechtel - 2007 - Psychology Press.
    A variety of scientific disciplines have set as their task explaining mental activities, recognizing that in some way these activities depend upon our brain. But, until recently, the opportunities to conduct experiments directly on our brains were limited. As a result, research efforts were split between disciplines such as cognitive psychology, linguistics, and artificial intelligence that investigated behavior, while disciplines such as neuroanatomy, neurophysiology, and genetics experimented on the brains of non-human animals. In recent decades these disciplines integrated, and with (...)
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  • How Scientists Explain Disease.Paul Thagard - 1999 - Princeton University Press.
    "This is a wonderful book! In "How Scientists Explain Disease," Paul Thagard offers us a delightful essay combining science, its history, philosophy, and sociology.
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  • Conceptual Revolutions.Paul Thagard - 1992 - Princeton: Princeton University Press.
    In this path-breaking work, Paul Thagard draws on history and philosophy of science, cognitive psychology, and the field of artificial intelligence to develop a ...
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  • The Brain and the Meaning of Life.Paul Thagard - 2010 - Princeton University Press.
    The book integrates decades of multidisciplinary research, but its clear explanations and humor make it accessible to the general reader.
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  • Mental Leaps: Analogy in Creative Thought.Keith J. Holyoak & Paul Thagard - 1995 - MIT Press.
    Keith Holyoak and Paul Thagard provide a unified, comprehensive account of the diverse operations and applications of analogy, including problem solving, ...
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  • A System of Logic.John Stuart Mill - 1874 - Longman.
    Reprint of the original, first published in 1869.
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  • Evaluating Explanations in Law, Science, and Everyday Life.Paul Thagard - unknown
    ��This article reviews a theory of explanatory coherence that provides a psychologically plausible account of how people evaluate competing explanations. The theory is implemented in a computational model that uses simple artificial neural networks to simulate many important cases of scientific and legal reasoning. Current research directions include extensions to emotional thinking and implementation in more biologically realistic neural networks.
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  • Thagard’s coherentism. [REVIEW]Majid Amini - 2000 - Philosophical Books 43 (2):136-140.
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  • Thought by Gilbert Harman. [REVIEW]Colin Radford - 1976 - Mind 85 (337):149-150.
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  • The environment and disease: association or causation?Austin Bradford Hill - 1965 - Proceedings of the Royal Society of Medicine 58 (5):295-300.
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  • Hill's Heuristics and Explanatory Coherentism in Epidemiology.Olaf Dammann - 2018 - American Journal of Epidemiology 187 (1):1-6.
    In this essay, I argue that Ted Poston's theory of explanatory coherentism is well-suited as a tool for causal explanation in the health sciences, particularly in epidemiology. Coherence has not only played a role in epidemiology for more than half a century as one of Hill's viewpoints, it can also provide background theory for the development of explanatory systems by integrating epidemiologic evidence with a diversity of other error-independent data. I propose that computational formalization of Hill's viewpoints in an explanatory (...)
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